Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Metabolic Syndrome Clinical Trials
Metabolic Syndrome clinical trials are recruiting across 33 cities. Here are the cities with the most active studies:
Metabolic Syndrome Trial Phases
21 research organizations are sponsoring metabolic syndrome trials.
About Metabolic Syndrome
Metabolic syndrome is a cluster of conditions including high blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol levels. It significantly increases the risk of heart disease, stroke, and type 2 diabetes. Management focuses on lifestyle changes and treating individual risk factors.
Clinical trials are advancing new treatments for metabolic syndrome. Currently, 23 studies are recruiting a combined 4,412 participants across the United States. Research is being conducted by 21 organizations including Massachusetts Institute of Technology, Ohio State University, NewAmsterdam Pharma and 18 others.
2026 Metabolic Syndrome Research Landscape
As of July 2026, the metabolic syndrome clinical trial landscape includes 23 actively recruiting studies across 33 cities in the United States. These studies are collectively seeking 4,412 participants, with an average enrollment target of 192 per study.
The research spans multiple phases of development: 13 studies are in NA, 6 studies are in PHASE2, 2 studies are in PHASE3, 2 studies are in PHASE1, 1 study is in PHASE4. The presence of Phase 3 trials indicates that some metabolic syndrome treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 21 different organizations, including Massachusetts Institute of Technology, Ohio State University, NewAmsterdam Pharma, Brown University, M.D. Anderson Cancer Center, and 16 others. The large number of sponsors reflects significant research interest and investment in metabolic syndrome treatment advancement.
Geographically, metabolic syndrome trials are most concentrated in Columbus, Ohio (2 trials); La Jolla, California (2 trials); Aurora, Colorado (2 trials); Secaucus, New Jersey (1 trial); Sun City West, Arizona (1 trial) and 7 other cities.
Featured Metabolic Syndrome Studies
Highlighted recruiting studies for metabolic syndrome, selected by enrollment size and research scope.
Wellness Program Outreach and Effectiveness
The investigators will conduct a randomized controlled trial to evaluate the impact of an outreach campaign designed to increase engagement with Pack Health, a Quest Diagnostics wellness program providing individual health coaching for weight management and diabetes prevention. While employee wellness and disease-management programs have the potential to improve wellbeing and reduce healthcare cos...
Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
Lower attainment of cardiovascular health (CVH), indicated by the American Heart Association's Life's Simple 7 (LS7; physical activity, diet, cholesterol, blood pressure, body mass index, smoking, glycemia) and Life's Essential 8 (LE8; LS7+sleep) metrics, is a major contributor to Black men having the shortest life-expectancy of any non-indigenous race/sex group. Unfortunately, a paucity of litera...
A Study to Evaluate the Effect of Obicetrapib/Ezetimibe 10 mg Fixed-Dose Combination or Obicetrapib 10 mg Daily on Top of Guideline-Recommended Lipid-Lowering Therapy in Participants With Type 2 Diabetes and/or Metabolic Syndrome
This study will be a placebo-controlled, double-blind, randomized, Phase 3 study to evaluate the efficacy, safety, and tolerability of obicetrapib 10 mg, both as a fixed-dose combination (FDC) with ezetimibe 10 mg and as monotherapy, on top of guideline-recommended lipid-lowering therapy in patients with metabolic syndrome and/or Type 2 Diabetes Mellitus.
Frequently Asked Questions About Metabolic Syndrome Clinical Trials
Are there metabolic syndrome clinical trials near me?
Yes, there are 23 metabolic syndrome clinical trials currently recruiting across 33+ cities in the United States, including Columbus, Ohio; La Jolla, California; Aurora, Colorado. Browse the studies above to find one at a location convenient for you.
How do I join a metabolic syndrome clinical trial?
To join a metabolic syndrome clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are metabolic syndrome clinical trials free?
Yes, participation in metabolic syndrome clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of metabolic syndrome treatments are being studied?
Current metabolic syndrome clinical trials are testing a range of approaches across NA (13 studies), PHASE2 (6 studies), PHASE3 (2 studies), PHASE1 (2 studies), PHASE4 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 21 research organizations.
Is it safe to participate in metabolic syndrome clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 16, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 16, 2026 · Data from ClinicalTrials.gov