Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for NASH Clinical Trials
NASH clinical trials are recruiting across 84 cities. Here are the cities with the most active studies:
NASH Trial Phases
33 research organizations are sponsoring nash trials.
About NASH
Nonalcoholic steatohepatitis (NASH/MASH) is a form of fatty liver disease involving liver inflammation and damage caused by fat buildup, not related to alcohol use. It can progress to fibrosis, cirrhosis, and liver failure. Treatment focuses on weight loss, lifestyle changes, and emerging pharmacological therapies.
Clinical trials are advancing new treatments for nash. Currently, 44 studies are recruiting a combined 26,724 participants across the United States. Research is being conducted by 33 organizations including Eli Lilly and Company, Akero Therapeutics, Inc, Altimmune, Inc. and 30 others.
2026 NASH Research Landscape
As of October 2026, the nash clinical trial landscape includes 44 actively recruiting studies across 84 cities in the United States. These studies are collectively seeking 26,724 participants, with an average enrollment target of 607 per study.
The research spans multiple phases of development: 14 studies are in PHASE2, 12 studies are in PHASE3, 5 studies are in PHASE1, 4 studies are in NA, 2 studies are in PHASE4. The presence of Phase 3 trials indicates that some nash treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 33 different organizations, including Eli Lilly and Company, Akero Therapeutics, Inc, Altimmune, Inc., Boehringer Ingelheim, GlaxoSmithKline, and 28 others. The large number of sponsors reflects significant research interest and investment in nash treatment advancement.
Geographically, nash trials are most concentrated in Tucson, Arizona (11 trials); Chandler, Arizona (10 trials); Peoria, Arizona (9 trials); Little Rock, Arkansas (9 trials); North Little Rock, Arkansas (5 trials) and 7 other cities.
Featured NASH Studies
Highlighted recruiting studies for nash, selected by enrollment size and research scope.
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
The main purpose of the SYNERGY-OUTCOMES study is to find out whether retatrutide and tirzepatide can prevent major adverse liver outcomes (MALO) in people with high-risk metabolic dysfunction-associated steatotic liver disease (MASLD). The study will enroll adults who have MASLD based on non-invasive tests (NITs), which indicate they are more likely to develop MALO. Participants will be randomly ...
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
This is a multi-center evaluation of efruxifermin (EFX) in a randomized, double-blind, placebo-controlled study in subjects with compensated cirrhosis due to NASH/MASH.
Phase 3 Study of the Efficacy, Safety, and Clinical Outcomes of Pemvidutide in MASH
Phase 3, multicenter, multinational, 2-cohort, randomized, double-blind, placebo controlled, parallel-group pivotal study to evaluate the efficacy, safety, and clinical outcomes of pemvidutide treatment in subjects with noncirrhotic (F2 or F3) metabolic dysfunction-associated steatohepatitis (MASH). Participants will be assigned either to Cohort 1 based on screening histologic (liver biopsy) crite...
Frequently Asked Questions About NASH Clinical Trials
Are there nash clinical trials near me?
Yes, there are 44 nash clinical trials currently recruiting across 84+ cities in the United States, including Tucson, Arizona; Chandler, Arizona; Peoria, Arizona. Browse the studies above to find one at a location convenient for you.
How do I join a nash clinical trial?
To join a nash clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are nash clinical trials free?
Yes, participation in nash clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of nash treatments are being studied?
Current nash clinical trials are testing a range of approaches across PHASE2 (14 studies), PHASE3 (12 studies), PHASE1 (5 studies), NA (4 studies), PHASE4 (2 studies). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 33 research organizations.
Is it safe to participate in nash clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated October 15, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated October 15, 2026 · Data from ClinicalTrials.gov