Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Thyroid Disease Clinical Trials
Thyroid Disease clinical trials are recruiting across 64 cities. Here are the cities with the most active studies:
Thyroid Disease Trial Phases
13 research organizations are sponsoring thyroid disease trials.
About Thyroid Disease
Thyroid disease encompasses conditions that affect the thyroid gland, including hypothyroidism (underactive), hyperthyroidism (overactive), Hashimoto's thyroiditis, and Graves' disease. The thyroid produces hormones that regulate metabolism. Treatment depends on the type and may include medication, radioactive iodine, or surgery.
Clinical trials are advancing new treatments for thyroid disease. Currently, 15 studies are recruiting a combined 7,966 participants across the United States. Research is being conducted by 13 organizations including AbbVie, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), University of Michigan and 10 others.
2026 Thyroid Disease Research Landscape
As of July 2026, the thyroid disease clinical trial landscape includes 15 actively recruiting studies across 64 cities in the United States. These studies are collectively seeking 7,966 participants, with an average enrollment target of 531 per study.
The research spans multiple phases of development: 6 studies are in PHASE2, 4 studies are in PHASE3, 2 studies are in PHASE4, 2 studies are in PHASE1, 1 study is in NA. The presence of Phase 3 trials indicates that some thyroid disease treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 13 different organizations, including AbbVie, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), University of Michigan, Biohaven Therapeutics Ltd., Immunovant Sciences GmbH, and 8 others. The large number of sponsors reflects significant research interest and investment in thyroid disease treatment advancement.
Geographically, thyroid disease trials are most concentrated in San Francisco, California (4 trials); Dallas, Texas (3 trials); Phoenix, Arizona (3 trials); Orange, California (3 trials); Miami, Florida (3 trials) and 7 other cities.
Featured Thyroid Disease Studies
Highlighted recruiting studies for thyroid disease, selected by enrollment size and research scope.
A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants
This study will evaluate the efficacy and safety of Armour Thyroid treatment compared with synthetic T4 in subjects who have primary hypothyroidism and are currently stabilized (i.e., in-range thyroid-stimulating hormone \[TSH\]) on synthetic T4 treatment. This study will also therefore evaluate the efficacy and safety of dose conversion from synthetic T4 therapy to Armour Thyroid therapy.
Natural History of Thyroid Function Disorders
Participants in this study will be patients diagnosed with or suspected to have a thyroid function disorder. These conditions may include: hypothyroidism, hyperthyroidism, thyroid hormone resistance, Graves' Dermopathy, and thyroid-stimulating hormone (TSH) secreting pituitary adenomas. The main purpose of this study is to further understand the natural history, clinical presentation, and genetic...
Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing
The proposed study focuses on testing a novel adapted evidence-based multilevel intervention, Deprescribing Thyroid Hormone In Older Adults (D-THIO), to support thyroid hormone deprescribing (dose de-escalation and/or discontinuation) in older adults with thyroid hormone overtreatment and/or misuse and reduce patient harm. Findings from this study will lay the groundwork for broad implementation o...
Frequently Asked Questions About Thyroid Disease Clinical Trials
Are there thyroid disease clinical trials near me?
Yes, there are 15 thyroid disease clinical trials currently recruiting across 64+ cities in the United States, including San Francisco, California; Dallas, Texas; Phoenix, Arizona. Browse the studies above to find one at a location convenient for you.
How do I join a thyroid disease clinical trial?
To join a thyroid disease clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are thyroid disease clinical trials free?
Yes, participation in thyroid disease clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of thyroid disease treatments are being studied?
Current thyroid disease clinical trials are testing a range of approaches across PHASE2 (6 studies), PHASE3 (4 studies), PHASE4 (2 studies), PHASE1 (2 studies), NA (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 13 research organizations.
Is it safe to participate in thyroid disease clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 16, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 16, 2026 · Data from ClinicalTrials.gov