A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants
This study will evaluate the efficacy and safety of Armour Thyroid treatment compared with synthetic T4 in subjects who have primary hypothyroidism and are currently stabilized (i.e., in-range thyroid...
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
This is a study to assess the efficacy, safety, and tolerability of IMVT-1402 in adult participants with Graves' disease (GD) who are hyperthyroid despite antithyroid drug (ATD) treatment. The primar...
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
This is a multi-center, global, randomized, double-blind, placebo-controlled Phase 2b study to assess the efficacy, safety, and tolerability of IMVT-1402 in adult participants with Graves' disease (GD...
Preoperative Corticosteroids in Autoimmune Thyroid Disease
This study proposes to randomize patients about to undergo surgery for their autoimmune, inflammatory thyroid disease, and determine if a short course of corticosteroids decreases the inflammation of ...
Top Cities for Thyroid Disease Clinical Trials
Thyroid Disease clinical trials are recruiting across 28 cities. Here are the cities with the most active studies:
About Thyroid Disease
Thyroid disease encompasses conditions that affect the thyroid gland, including hypothyroidism (underactive), hyperthyroidism (overactive), Hashimoto's thyroiditis, and Graves' disease. The thyroid produces hormones that regulate metabolism. Treatment depends on the type and may include medication, radioactive iodine, or surgery.
Clinical trials are advancing new treatments for thyroid disease. Currently, 4 studies are recruiting a combined 3,326 participants across the United States. Research is being conducted by 3 organizations including AbbVie, Immunovant Sciences GmbH, Indiana University.
2026 Thyroid Disease Research Landscape
As of March 2026, the thyroid disease clinical trial landscape includes 4 actively recruiting studies across 28 cities in the United States. These studies are collectively seeking 3,326 participants, with an average enrollment target of 832 per study.
Research is being led by 3 different organizations, including AbbVie, Immunovant Sciences GmbH, Indiana University.
Geographically, thyroid disease trials are most concentrated in Indianapolis, Indiana (3 trials); Birmingham, Alabama (2 trials); Concord, California (2 trials); Phoenix, Arizona (2 trials); Bonita, California (1 trial) and 7 other cities.
Featured Thyroid Disease Studies
Highlighted recruiting studies for thyroid disease, selected by enrollment size and research scope.
A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants
This study will evaluate the efficacy and safety of Armour Thyroid treatment compared with synthetic T4 in subjects who have primary hypothyroidism and are currently stabilized (i.e., in-range thyroid-stimulating hormone \[TSH\]) on synthetic T4 treatment. This study will also therefore evaluate the efficacy and safety of dose conversion from synthetic T4 therapy to Armour Thyroid therapy.
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
This is a study to assess the efficacy, safety, and tolerability of IMVT-1402 in adult participants with Graves' disease (GD) who are hyperthyroid despite antithyroid drug (ATD) treatment. The primary objective of this study is to evaluate the efficacy of IMVT-1402 versus placebo as assessed by T3 (total triiodothyronine \[T3\] or free triiodothyronine \[FT3\]), free thyroxine (FT4), thyroid-stim...
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
This is a multi-center, global, randomized, double-blind, placebo-controlled Phase 2b study to assess the efficacy, safety, and tolerability of IMVT-1402 in adult participants with Graves' disease (GD) who are hyperthyroid despite antithyroid drug (ATD) treatment.
Frequently Asked Questions About Thyroid Disease Clinical Trials
Are there thyroid disease clinical trials near me?
Yes, there are 4 thyroid disease clinical trials currently recruiting across 28+ cities in the United States, including Indianapolis, Indiana; Birmingham, Alabama; Concord, California. Browse the studies above to find one at a location convenient for you.
How do I join a thyroid disease clinical trial?
To join a thyroid disease clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are thyroid disease clinical trials free?
Yes, participation in thyroid disease clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of thyroid disease treatments are being studied?
Current thyroid disease clinical trials are testing a range of approaches. These include new drugs, combination therapies, medical devices, and other interventions sponsored by 3 research organizations.
Is it safe to participate in thyroid disease clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated March 2, 2026 from ClinicalTrials.gov
About This Data
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated March 2, 2026 · Data from ClinicalTrials.gov