Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout
The TRUST study is a randomized, controlled multicenter study to evaluate the management of gout by comparing two commonly used treatment strategies for gout (TTT vs TTASx) to determine the most benef...
A Study of Dotinurad Versus Allopurinol in Participants With Gout
The primary objective of this study is to evaluate the efficacy of dotinurad in lowering serum uric acid (sUA) at Week 24 compared with allopurinol in adult participants with hyperuricemia associated ...
Safety and Efficacy of ABP-745 in Participants With an Acute Gout Flare
A randomized, double-blind, international multicenter, colchicine and placebo-controlled study to evaluate the efficacy and safety of ABP-745 in subjects with acute gout. Efficacy of ABP-745 in reduci...
Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare
The purpose of this trial is to investigate the efficacy and safety of dapansutrile (OLT1177®) tablets in subjects with an acute gout flare....
A Study of Dotinurad Versus Allopurinol in Tophaceous Gout
The primary objective of this study is to evaluate the efficacy of dotinurad in lowering serum uric acid (sUA) at Week 24 compared with allopurinol in adult participants with tophaceous gout....
Top Cities for Gout Clinical Trials
Gout clinical trials are recruiting across 29 cities. Here are the cities with the most active studies:
About Gout
Gout is a form of inflammatory arthritis caused by elevated levels of uric acid in the blood, leading to crystal deposits in joints. It causes sudden, severe episodes of pain, swelling, and redness. Treatment includes anti-inflammatory medications for flares and urate-lowering therapy for prevention.
Clinical trials are advancing new treatments for gout. Currently, 5 studies are recruiting a combined 2,080 participants across the United States. Research is being conducted by 4 organizations including Massachusetts General Hospital, Crystalys Therapeutics, Atom Therapeutics Co., Ltd and 1 others.
2026 Gout Research Landscape
As of March 2026, the gout clinical trial landscape includes 5 actively recruiting studies across 29 cities in the United States. These studies are collectively seeking 2,080 participants, with an average enrollment target of 416 per study.
Research is being led by 4 different organizations, including Massachusetts General Hospital, Crystalys Therapeutics, Atom Therapeutics Co., Ltd, Olatec Therapeutics LLC.
Geographically, gout trials are most concentrated in Boston, Massachusetts (3 trials); San Diego, California (3 trials); Tampa, Florida (3 trials); Dublin, California (2 trials); Coral Gables, Florida (2 trials) and 7 other cities.
Featured Gout Studies
Highlighted recruiting studies for gout, selected by enrollment size and research scope.
Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout
The TRUST study is a randomized, controlled multicenter study to evaluate the management of gout by comparing two commonly used treatment strategies for gout (TTT vs TTASx) to determine the most beneficial for a patient-centered gout outcomes, as well as relevant cardiovascular-metabolic-renal endpoints.
A Study of Dotinurad Versus Allopurinol in Participants With Gout
The primary objective of this study is to evaluate the efficacy of dotinurad in lowering serum uric acid (sUA) at Week 24 compared with allopurinol in adult participants with hyperuricemia associated with gout.
Safety and Efficacy of ABP-745 in Participants With an Acute Gout Flare
A randomized, double-blind, international multicenter, colchicine and placebo-controlled study to evaluate the efficacy and safety of ABP-745 in subjects with acute gout. Efficacy of ABP-745 in reducing pain and swelling compared with standard colchicine treatment and placebo will be evaluated in participants with acute gout. The primary efficacy measurement will be pain score after treatment.
Frequently Asked Questions About Gout Clinical Trials
Are there gout clinical trials near me?
Yes, there are 5 gout clinical trials currently recruiting across 29+ cities in the United States, including Boston, Massachusetts; San Diego, California; Tampa, Florida. Browse the studies above to find one at a location convenient for you.
How do I join a gout clinical trial?
To join a gout clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are gout clinical trials free?
Yes, participation in gout clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of gout treatments are being studied?
Current gout clinical trials are testing a range of approaches. These include new drugs, combination therapies, medical devices, and other interventions sponsored by 4 research organizations.
Is it safe to participate in gout clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated March 2, 2026 from ClinicalTrials.gov
About This Data
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated March 2, 2026 · Data from ClinicalTrials.gov