Aurora, ILLINOIS5 Active Studies

Head and Neck Cancer Clinical Trials in Aurora, ILLINOIS

Find 5 actively recruiting head and neck cancer clinical trials in Aurora, ILLINOIS. Connect with local research sites and explore new treatment options.

5
Active Trials
5
Sponsors
1,235
Enrolling

Recruiting Head and Neck Cancer Studies in Aurora

RecruitingAurora, ILLINOISNCT06788990

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

Ficerafusp alfa is directed against two targets, Epidermal Growth Factor Receptor (EGFR) and Transforming Growth Factor beta (TGF-β). This study intends to evaluate the safety and efficacy of ficeraf...

650 participants
Bicara Therapeutics
View Study Details
RecruitingAurora, ILLINOISNCT06385080

A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Recurrent/Metastatic Head and Neck Cancer

The purpose of this study is to determine safety and preliminary efficacy of amivantamab monotherapy, amivantamab in addition to pembrolizumab, amivantamab in addition to paclitaxel and amivantamab in...

247 participants
Janssen Research & Development, LLC
View Study Details
RecruitingAurora, ILLINOISNCT06992427

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

This phase III trial tests if gabapentin can prevent the need for opiate pain medication for mouth sores (oral mucositis) in patients undergoing treatment with chemotherapy and radiation for squamous ...

228 participants
Alliance for Clinical Trials in Oncology
View Study Details
RecruitingAurora, ILLINOISNCT05814666

Activity and Safety of Danvatirsen and Pembrolizumab in HNSCC

Open-label, Phase II, randomized, controlled study evaluating the efficacy and safety of danvatirsen in combination with pembrolizumab compared with pembrolizumab alone as first-line treatment of pati...

81 participants
Flamingo Therapeutics NV
View Study Details
RecruitingAurora, ILLINOISNCT06919666

NT219 Combined With Standard of Care Biologic Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Fixed dose NT219 weekly plus pembrolizumab every 3 weeks or cetuximab weekly to be continued until progression, unacceptable toxicity, or investigator or participant decision....

29 participants
University of Colorado, Denver
View Study Details

About Head and Neck Cancer Clinical Trials in Aurora

Head and neck cancers develop in the mouth, throat, larynx, sinuses, or salivary glands. HPV-related oropharyngeal cancers have been increasing in prevalence. Treatment includes surgery, radiation, chemotherapy, and immunotherapy.

There are currently 5 head and neck cancer clinical trials recruiting participants in Aurora, ILLINOIS. These studies are seeking a combined 1,235 participants. Research is being sponsored by Bicara Therapeutics, Janssen Research & Development, LLC, Alliance for Clinical Trials in Oncology and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Head and Neck Cancer Clinical Trials in Aurora — FAQ

Are there head and neck cancer clinical trials in Aurora?

Yes, there are 5 head and neck cancer clinical trials currently recruiting in Aurora, ILLINOIS. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Aurora?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Aurora research site will contact you about next steps.

Are clinical trials in Aurora free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Aurora studies also compensate for your time and travel.

What head and neck cancer treatments are being tested?

The 5 active trials in Aurora are testing new therapies including novel drugs, biologics, and treatment approaches for head and neck cancer.

Data updated March 2, 2026 from ClinicalTrials.gov