6 Neurofibromatosis Clinical Trials in Baltimore, MD (2026)

Q: How do I join a clinical trial in Baltimore?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Baltimore research site will contact you.

Recruiting Neurofibromatosis Studies in Baltimore

NCT02544022Recruiting

Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)

Background: People with neurofibromatosis 1 (NF1) who have plexiform neurofibromas (pNFs) can have pain that affects their daily lives. This study aims to improve questionnaires that measure their pa...

Baltimore, MD476 participantsNational Cancer Institute (NCI)

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NCT06188741Recruiting

Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1

Plexiform neurofibromas (PN) are known to cause significant morbidity in children with NF1. The recent FDA approval for selumetinib in children 2 years and older with inoperable symptomatic PN was bas...

Baltimore, MDPHASE2200 participantsUniversity of Alabama at Birmingham

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NCT04374305Recruiting

Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)

This is a multi-arm phase II platform-basket screening study designed to test multiple experimental therapies simultaneously in patients with NF2-related schwannomatosis (NF2-SWN, formerly known as ne...

Baltimore, MDPHASE2109 participantsScott R. Plotkin, MD, PhD

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NCT06541847Recruiting

A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1

The trial will be an open label, single arm, phase 2 study in 20 participants. The study will assess the tolerability and efficacy of HLX-1502 in participants with NF1 16 years of age or older with pr...

Baltimore, MDPHASE225 participantsHealx Limited

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NCT06159166Recruiting

Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF).

This is a Phase 1/2a, open-label, non-randomized, multi-dose study of mirdametinib monotherapy in adults with NF1 and cNF. In both Phases of the study, participation in the study will comprise three ...

Baltimore, MDPHASE124 participantsJohns Hopkins University

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NCT07102394Recruiting

Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1

This study is designed to establish the foundation for a new therapy for neurofibromatosis Type I (NF1)-related cutaneous neurofibromas (cNFs) by assessing the feasibility and efficacy of IMLYGIC in a...

Baltimore, MDPHASE110 participantsJohns Hopkins University

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About Neurofibromatosis Clinical Trials in Baltimore

Neurofibromatosis is a group of genetic conditions that cause tumors to grow on nerve tissue. NF1 is the most common type, causing skin changes and bone deformities. Treatment includes monitoring, surgery for problematic tumors, and MEK inhibitors for plexiform neurofibromas.

There are currently 6 neurofibromatosis clinical trials recruiting participants in Baltimore, MD. These studies are seeking a combined 844 participants. Research is being sponsored by National Cancer Institute (NCI), University of Alabama at Birmingham, Scott R. Plotkin, MD, PhD and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Neurofibromatosis Clinical Trials in Baltimore — FAQ

Are there neurofibromatosis clinical trials in Baltimore?

Yes, there are 6 neurofibromatosis clinical trials currently recruiting in Baltimore, MD. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Baltimore?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Baltimore research site will contact you about next steps.

Are clinical trials in Baltimore free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Baltimore studies also compensate for your time and travel.

What neurofibromatosis treatments are being tested?

The 6 active trials in Baltimore are testing new therapies including novel drugs, biologics, and treatment approaches for neurofibromatosis.

Data updated October 16, 2026 from ClinicalTrials.gov