51 Osteogenesis Imperfecta Clinical Trials in Baltimore, MD (2026)

Q: How do I join a clinical trial in Baltimore?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Baltimore research site will contact you.

Recruiting Osteogenesis Imperfecta Studies in Baltimore

NCT03013998Recruiting

Study of Biomarker-Based Treatment of Acute Myeloid Leukemia

This screening and multi-sub-study Phase 1b/2 trial will establish a method for genomic screening followed by assigning and accruing simultaneously to a multi-study "Master Protocol (BAML-16-001-M1)."...

Baltimore, MD3,000 participantsBeat AML, LLC

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NCT04561518Recruiting

ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

The purpose of this study is to: * Describe epidemiological and clinical characteristics, natural history and real-world clinical management of ATTR amyloidosis patients * Characterize the safety and...

Baltimore, MD1,500 participantsAlnylam Pharmaceuticals

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NCT02432625Recruiting

BBD Longitudinal Study of Osteogenesis Imperfecta

Osteogenesis Imperfecta (OI) is a rare disorder of increased bone fragility characterized by fractures with minimal or absent trauma, dentinogenesis imperfecta (DI), and, in adult years, hearing loss....

Baltimore, MD1,000 participantsBaylor College of Medicine

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NCT05865301Recruiting

Outcomes in Pediatric and Young Adult B-Cell Malignancies After Commercially Available Immunotherapy

To use a consistent and standardized platform to retrospectively and prospectively study children and young adults with B cell malignancies receiving Immunotherapy, blinatumomab and/or inotuzumab ozog...

Baltimore, MD500 participantsStanford University

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NCT06513156Recruiting

Continuum of Care in Hospitalized Patients With Opioid/Stimulant Use Disorder and Infectious Complications From Drug Use

This is a two-group randomized controlled trial conducted at five hospitals across the U.S. designed to test the effectiveness of an Integrated infectious diseases/Substance Use Disorder outpatient cl...

Baltimore, MD304 participantsElana Rosenthal

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NCT05357378Recruiting

Safety and Effectiveness of the HIT Reverse HRS

The purpose of this study is to determine if the use of the HIT Reverse Hip Replacement System is safe and effective in patients undergoing total hip replacement. We will determine whether it is safe ...

Baltimore, MD288 participantsHip Innovation Technology

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NCT06190730Recruiting

REmote Symptom COllection to improVE postopeRative Care

There are vulnerabilities in post-discharge care transition for patients after undergoing resection of malignant gastrointestinal tumors. This study aims to investigate the possibility of utilizing Vo...

Baltimore, MD281 participantsMedstar Health Research Institute

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NCT04260022Recruiting

Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL

A multi-center, open-label, randomized, phase Ib study to evaluate the pharmacokinetics (PK) of HQP1351 and to determine the recommended phase 2 dose (RP2D) of HQP1351 in subjects with CML chronic pha...

Baltimore, MD242 participantsAscentage Pharma Group Inc.

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NCT03705585Recruiting

CVD 38000: Study of Responses to Vaccination With Typhoid and/or Cholera

This is an open-label, non-randomized study. The purpose of this study is to better understand how vaccines against typhoid fever and cholera affect the normal immune system and bacteria in the intest...

Baltimore, MD240 participantsUniversity of Maryland, Baltimore

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NCT06306443Recruiting

Buprenorphine for Individuals in Jail

This study is an open label randomized controlled trial of extended-release buprenorphine (BRIXADI, XR-B) vs. sublingual buprenorphine (SL-B) in a large metropolitan jail. An open-label design will ra...

Baltimore, MD240 participantsFriends Research Institute, Inc.

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NCT07214311Recruiting

Evaluation of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Knee Arthroplasty

The goal of this clinical trial is to evaluate whether the investigational drug PLG0206 can help reduce recurrence of infection in adults who have undergone total knee replacement and are receiving a ...

Baltimore, MD240 participantsPeptilogics

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NCT05605574Recruiting

Longitudinal Early Advance Care Planning Discussions and Documentation (LEADD) Program: An Exploratory Study in Adolescents and Young Adults (AYAs) Receiving Hematopoietic Stem Cell Transplant

Background: For adolescent and young adults (AYAs) with certain life-threatening illnesses, hematopoietic stem cell transplant (HSCT) provides the best chance for cure and survival. HSCT is a life-sa...

Baltimore, MD222 participantsNational Cancer Institute (NCI)

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NCT05567133Recruiting

Risk Indicators of Sarcoidosis Evolution-Unified Protocol

The purpose of this study is to develop prediction models that can prognosticate patients with sarcoidosis using clinical data and blood markers that can be obtained during a clinic visit....

Baltimore, MD200 participantsUniversity of California, San Francisco

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NCT06548490Recruiting

GLP-1R Agonist Treatment for Opioid Use Disorder

The goal of this clinical trial is to learn if semaglutide can reduce illicit opioid use in adults in outpatient treatment for opioid use disorder, and who are receiving either buprenorphine or methad...

Baltimore, MD200 participantsMilton S. Hershey Medical Center

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NCT06008795Recruiting

BLOCK-SAH - PPF-Block for Post-SAH Headache

BLOCK-SAH is a phase II, multicenter, randomized, double-blinded, placebo-controlled clinical trial with a sequential parallel comparison design (SPCD) of bilateral pterygopalatine fossa (PPF) injecti...

Baltimore, MD195 participantsUniversity of Florida

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NCT06135870Recruiting

Role of Senescent Cells in Uterine Fibroid Pathogenesis (SOUL Study)

The investigators are evaluating the role of senescent cells in uterine fibroids....

Baltimore, MD150 participantsJohns Hopkins University

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NCT04173416Recruiting

The Youth Opioid Recovery Support (YORS) Intervention

Youth are disproportionately affected by the current opioid crisis with catastrophic consequences, and young adults with opioid use disorder (OUD) often struggle with adherence to relapse prevention m...

Baltimore, MD150 participantsPotomac Health Foundations

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NCT03745339Recruiting

Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder

Background: People with addictions often find it hard to choose the long-term benefits of abstinence over the short-term effects of using drugs. Researchers think this is partly due to parts of the b...

Baltimore, MD150 participantsNational Institute on Drug Abuse (NIDA)

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NCT05995535Recruiting

Pregabalin Plus Lofexidine for the Outpatient Treatment of Opioid Withdrawal

A placebo-controlled trial in which male and female outpatients with an opioid use disorder who express interest in extended-release injectable naltrexone (XR-NTX) are randomized 1:1 to lofexidine/pre...

Baltimore, MD150 participantsUniversity of Pennsylvania

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NCT05459402Recruiting

Divided or Single Exposure (DOSE) Study

This study will evaluate whether once versus twice daily dosing of methadone will be an effective method for managing comorbid pain and opioid use disorder....

Baltimore, MD150 participantsUniversity of Maryland, Baltimore

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NCT06824168Recruiting

Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission

This clinical two-arm trial is designed to evaluate two doses of quizartinib as maintenance therapy after induction/consolidation in participants with FMS-like tyrosine kinase 3 (FLT3)-internal tandem...

Baltimore, MD130 participantsDaiichi Sankyo

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NCT05362773Recruiting

A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies

CP-MGD024-01 is a Phase 1, open-label, multi-center study of MGD024 as a single agent in participants with select blood cancers that have not responded to treatment with standard therapies or who have...

Baltimore, MD130 participantsMacroGenics

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NCT06954402Recruiting

Resilience Among Individuals With Opioid Use Disorder

The goal of this clinical trial is to develop a human laboratory model of resilience in people with opioid use disorder (OUD). The investigators aim to learn if objective tasks that measure cognitive,...

Baltimore, MD125 participantsJohns Hopkins University

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NCT07223203Recruiting

TRITON-PN: A Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy

The purpose of this study is to: * Determine the efficacy of nucresiran in patients with hATTR-PN by evaluating the effect on neurologic impairment, quality of life, nutritional status, disability, a...

Baltimore, MD125 participantsAlnylam Pharmaceuticals

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NCT06714591Recruiting

Evaluate the Safety, Tolerability, Pharmacokinetic Profile, Efficacy of Bl-M11D1

The objective of this study to evaluate the safety, tolerability, pharmacokinetic profile, and preliminary efficacy of BL-M11D1 in patients with relapsed/refractory acute myeloid leukemia....

Baltimore, MD120 participantsSystImmune Inc.

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NCT07003100Recruiting

A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab

This study is being done to assess mogamulizumab-associated rash in patients diagnosed with mycosis fungoides or sezary syndrome and treated with standard of care mogamulizumab. One of the most common...

Baltimore, MD100 participantsCity of Hope Medical Center

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NCT05511909Recruiting

Evaluating Buspirone to Treat Opioid Withdrawal

The investigators propose a rigorous, Phase II, three-group, placebo-controlled double-blind randomized controlled trial (RCT) to evaluate the efficacy of buspirone for both withdrawal and craving amo...

Baltimore, MD100 participantsUniversity of Maryland, Baltimore

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NCT06205121Recruiting

Efficacy and Safety Study of OATD-01 in Patients With Active Pulmonary Sarcoidosis

This is a Phase 2, randomized, double-blind, placebo-controlled, adaptive, multicenter study to evaluate the efficacy, safety, tolerability, Pharmacodynamics (PD), and Pharmacokinetics (PK) of OATD-01...

Baltimore, MD96 participantsMolecure S.A.

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NCT05890729Recruiting

A Study of XTMAB-16 in Patients With Pulmonary Sarcoidosis

A phase 1b/2 study of XTMAB-16 in patients with pulmonary sarcoidosis...

Baltimore, MD94 participantsXentria, Inc.

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NCT06067737Recruiting

Outpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder

This study will examine the effect of a single high dose of psilocybin therapy (30 mg) versus a very low dose (1 mg) as an adjunctive therapy to individuals undergoing standard-of-care outpatient bupr...

Baltimore, MD90 participantsJohns Hopkins University

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NCT05109429Recruiting

Developing a Clinical Outcome Assessment for Opioid Craving

The purpose of this study is to collect information about opioid craving so that the investigators can develop an opioid craving assessment to improve treatments for individuals with opioid use disord...

Baltimore, MD81 participantsJohns Hopkins University

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NCT06774248Recruiting

Expanding the Youth Opioid Recovery Support (YORS) Intervention for MOUD Adherence to Adolescents With OUD

Despite rising rates of fatal opioid overdoses in the United States, adolescents with OUD are far less likely than adults to receive and be retained on medication for opioid use disorder (MOUD). The m...

Baltimore, MD80 participantsPotomac Health Foundations

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NCT05829655Recruiting

Measuring Acute Drug Demand in Humans

This research is being done to evaluate whether suvorexant may reduce the use of, subjective liking, and demand for various drugs....

Baltimore, MD75 participantsUniversity of Maryland, Baltimore

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NCT03400826Recruiting

Effects of Simvastatin on Uterine Leiomyoma Size

The study aims to study the effect of simvastatin on the size of uterine fibroids....

Baltimore, MD60 participantsJohns Hopkins University

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NCT05027919Recruiting

Assessing a Clinically-meaningful Opioid Withdrawal Phenotype

Evaluate individual differences in the expression of opioid withdrawal symptoms in persons with opioid use disorder (OUD) while completing a clinically-indicated medication taper....

Baltimore, MD60 participantsUniversity of Maryland, Baltimore

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NCT06660732Recruiting

Rilonacept in Subjects With Cardiac Sarcoidosis

The primary objective of this study is to evaluate the effect of rilonacept, added to standard therapy and compared with standard therapy alone, on improvement in myocardial inflammation in subjects w...

Baltimore, MD60 participantsMayo Clinic

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NCT06484062Recruiting

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

This phase I trial tests the safety, side effects, and best dose of SM08502 (cirtuvivint) alone and in combination with ASTX727 in treating patients with acute myeloid leukemia (AML) and myelodysplast...

Baltimore, MD54 participantsNational Cancer Institute (NCI)

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NCT05546580Recruiting

Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+)

Iadademstat is being studied as a treatment for subjects with Relapsed or Refractory Acute Myeloid Leukemia (R/R AML) with FMS-like tyrosine kinase mutation (FLT3 mut+). During the trial, iadademstat ...

Baltimore, MD50 participantsOryzon Genomics S.A.

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NCT02203903Recruiting

Multi-institutional Prospective Research of Expanded Multi-antigen Specifically Oriented Lymphocytes for the Treatment of VEry High Risk Hematopoietic Malignancies

This Phase I dose-escalation trial is designed to evaluate the safety of administering rapidly -generated tumor multi-antigen associated -specific cytotoxic T lymphocytes, to HSCT recipients with high...

Baltimore, MD50 participantsCatherine Bollard

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NCT06943859Recruiting

Ketamine for Opioid Use Disorder

The goal of this clinical trial is to learn if ketamine works to reduce craving for opioids in adults entering methadone treatment for opioid use disorder. The main questions it aims to answer are: *...

Baltimore, MD50 participantsUniversity of Maryland, Baltimore

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NCT04892303Recruiting

Combination Radiotherapy and Radiopharmaceutical Therapy Treatment Planning for Thyroid Cancer

The goal of this study is to evaluate combined radioactive iodine (RAI, 131-I) and external beam radiotherapy (XRT) to optimize the radiation dose delivered to treat well differentiated thyroid cancer...

Baltimore, MD48 participantsSidney Kimmel Comprehensive Cancer Center at Johns Hopkins

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NCT04050280Recruiting

CLAG-GO for Patients With Persistent, Relapsed or Refractory AML

This study involves evaluating a combination of chemotherapy drugs known as "CLAG-GO" \[cladribine, cytarabine, granulocyte-colony stimulating factor (G-CSF) and gemtuzumab ozogamicin (GO)\] in the tr...

Baltimore, MD39 participantsUniversity of Maryland, Baltimore

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NCT06434233Recruiting

Opioid Use After Laparoscopic Salpingectomy

The purpose of this study is to evaluate patient-reported post-operative pain scores following minimally invasive tubal sterilization procedures to determine if a multimodal, non-opioid pain control r...

Baltimore, MD38 participantsJohns Hopkins University

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NCT06696157Recruiting

EXPANDED SCOPE for Parent Grant Entitled, "Peer Recovery Support Services for Individuals in Recovery Residences on MOUD"

The United States is experiencing an unprecedented opioid epidemic. Medications for opioid use disorder (MOUD), such as methadone, buprenorphine, and extended-release naltrexone, are the recommended s...

Baltimore, MD35 participantsPotomac Health Foundations

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NCT03201094Recruiting

Impact of NMES and HPRO on Recovery After SAH- Pilot Study

The study purpose is to investigate the hypothesis that in adults with SAH, early neuromuscular electrical stimulation (NMES) and high protein supplementation (HPRO) will improve muscle mass, metaboli...

Baltimore, MD30 participantsUniversity of Maryland, Baltimore

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NCT07153029Recruiting

Older Adults, Methadone, and Cognitive Function

The increasing prevalence of opioid use disorder (OUD) among older adults, coupled with high overdose rates and cognitive impairments associated with opioid use, highlights a critical gap in addiction...

Baltimore, MD30 participantsUniversity of Maryland, Baltimore

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NCT04197921Recruiting

Exablate for LIFU Neuromodulation in Patients With Opioid Use Disorder (OUD) and/or Other Substance Use Disorders (SUDs)

The purpose of this clinical trial is to investigate Low Intensity Focused Ultrasound (LIFU) using the Exablate® Model 4000 Type 2.0/2.1 as an adjunctive neuromodulatory treatment for OUD (Opioid Use ...

Baltimore, MD29 participantsInSightec

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NCT06089707Recruiting

Behavioral Pharmacological Examination of a Novel Buprenorphine Induction Method Among Individuals Who Use Fentanyl

The opioid overdose epidemic has persisted for several decades and is now further complicated by the permeation of fentanyl into the illicit opioid supply. While the effectiveness of medications to tr...

Baltimore, MD25 participantsJohns Hopkins University

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NCT06383091Recruiting

Impact of Manual Therapy on Laryngeal Function Following Total Thyroidectomy

In this clinical trial, the investigators are seeking to learn if a course of voice therapy, including neck massage, stretches and pain science education in addition to voice exercise and scar massage...

Baltimore, MD20 participantsJohns Hopkins University

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NCT03517579Recruiting

Personalized Treatment in Thyroid Disorders

The Collar Therapy Indicator (CoTI) (A device that is placed in collar around the neck resembling a turtle neck sweater collar with a wire and recording box) has been shown in a single small previousl...

Baltimore, MD10 participantsJohns Hopkins University

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NCT06284486Recruiting

A Multi-Site Break Through Cancer Trial: Phase II Study Investigating Dual Inhibition of BCL2 and Menin in AML MRD Using the Combination of Venetoclax and Revumenib

To learn if the combination of venetoclax and revumenib can help to control MRD-positive AML....

Baltimore, MD8 participantsM.D. Anderson Cancer Center

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About Osteogenesis Imperfecta Clinical Trials in Baltimore

Osteogenesis imperfecta is a group of genetic disorders mainly affecting the bones, causing them to break easily, often from little or no apparent cause. It is caused by defects in collagen production. Treatment includes bisphosphonates, physical therapy, and surgical rodding.

There are currently 51 osteogenesis imperfecta clinical trials recruiting participants in Baltimore, MD. These studies are seeking a combined 11,444 participants. Research is being sponsored by Beat AML, LLC, Alnylam Pharmaceuticals, Baylor College of Medicine and 28 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Osteogenesis Imperfecta Clinical Trials in Baltimore — FAQ

Are there osteogenesis imperfecta clinical trials in Baltimore?

Yes, there are 51 osteogenesis imperfecta clinical trials currently recruiting in Baltimore, MD. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Baltimore?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Baltimore research site will contact you about next steps.

Are clinical trials in Baltimore free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Baltimore studies also compensate for your time and travel.

What osteogenesis imperfecta treatments are being tested?

The 51 active trials in Baltimore are testing new therapies including novel drugs, biologics, and treatment approaches for osteogenesis imperfecta.

Data updated July 13, 2026 from ClinicalTrials.gov