Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Osteogenesis Imperfecta Clinical Trials
Osteogenesis Imperfecta clinical trials are recruiting across 157 cities. Here are the cities with the most active studies:
Osteogenesis Imperfecta Trial Phases
69 research organizations are sponsoring osteogenesis imperfecta trials.
About Osteogenesis Imperfecta
Osteogenesis imperfecta is a group of genetic disorders mainly affecting the bones, causing them to break easily, often from little or no apparent cause. It is caused by defects in collagen production. Treatment includes bisphosphonates, physical therapy, and surgical rodding.
Clinical trials are advancing new treatments for osteogenesis imperfecta. Currently, 100 studies are recruiting a combined 487,059 participants across the United States. Research is being conducted by 69 organizations including Frederic T Billings IV, AstraZeneca, University of Washington and 66 others.
2026 Osteogenesis Imperfecta Research Landscape
As of July 2026, the osteogenesis imperfecta clinical trial landscape includes 100 actively recruiting studies across 157 cities in the United States. These studies are collectively seeking 487,059 participants, with an average enrollment target of 4,871 per study.
The research spans multiple phases of development: 30 studies are in NA, 10 studies are in PHASE3, 4 studies are in PHASE2, 2 studies are in PHASE1, 2 studies are in PHASE4. The presence of Phase 3 trials indicates that some osteogenesis imperfecta treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 69 different organizations, including Frederic T Billings IV, AstraZeneca, University of Washington, BioDelivery Sciences International, Pfizer, and 64 others. The large number of sponsors reflects significant research interest and investment in osteogenesis imperfecta treatment advancement.
Geographically, osteogenesis imperfecta trials are most concentrated in San Francisco, California (12 trials); Chicago, Illinois (12 trials); Los Angeles, California (11 trials); Aurora, Colorado (11 trials); Rochester, Minnesota (11 trials) and 7 other cities.
Featured Osteogenesis Imperfecta Studies
Highlighted recruiting studies for osteogenesis imperfecta, selected by enrollment size and research scope.
Impact of Intraoperative Oxygenation Practices on Patient Outcomes
This multicenter, cluster-randomized, cluster-crossover clinical trial evaluates the impact of three intraoperative FiO2 (Fraction of Inspired Oxygen) oxygenation strategies-lower (FiO₂ 0.21-0.40), intermediate (FiO₂ 0.40-0.80), and higher (FiO₂ 0.80-1.00)-on postoperative organ injury and mortality in adult surgical patients. The trial aims to determine the optimal oxygenation strategy to improve...
OverTTuRe: Characteristics, Treatment Patterns and Outcomes of Patients With ATTR Amyloidosis
The overall aim of this observational study is to generate real-world evidence on the pre- and post-diagnosis disease journeys, including baseline characteristics, treatment patterns and selected clinical, economic, and humanistic outcomes (for example Health Related Quality of Life (HRQoL), Neuropathy impairment score, activities of daily living (ADL) assessments) in patients with ATTR amyloidosi...
Overdose Recovery and Care Access (ORCA) Qualitative Stakeholder Interviews and County-level Data
The study is a quasi-experimental investigation of a sub-acute stabilization center (SASC) for people who have had or are at risk for having an opioid overdose and have an encounter with Seattle Fire Department emergency medical services (EMS) in Seattle, WA. Those transported to the SASC are the intervention participants and two comparison groups will be utilized: eligible Seattle EMS patients wh...
Frequently Asked Questions About Osteogenesis Imperfecta Clinical Trials
Are there osteogenesis imperfecta clinical trials near me?
Yes, there are 100 osteogenesis imperfecta clinical trials currently recruiting across 157+ cities in the United States, including San Francisco, California; Chicago, Illinois; Los Angeles, California. Browse the studies above to find one at a location convenient for you.
How do I join a osteogenesis imperfecta clinical trial?
To join a osteogenesis imperfecta clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are osteogenesis imperfecta clinical trials free?
Yes, participation in osteogenesis imperfecta clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of osteogenesis imperfecta treatments are being studied?
Current osteogenesis imperfecta clinical trials are testing a range of approaches across NA (30 studies), PHASE3 (10 studies), PHASE2 (4 studies), PHASE1 (2 studies), PHASE4 (2 studies). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 69 research organizations.
Is it safe to participate in osteogenesis imperfecta clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 19, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 19, 2026 · Data from ClinicalTrials.gov