San Francisco, CALIFORNIA18 Active Studies

Osteogenesis Imperfecta Clinical Trials in San Francisco, CALIFORNIA

Find 18 actively recruiting osteogenesis imperfecta clinical trials in San Francisco, CALIFORNIA. Connect with local research sites and explore new treatment options.

18
Active Trials
18
Sponsors
6,220
Enrolling

Recruiting Osteogenesis Imperfecta Studies in San Francisco

RecruitingSan Francisco, CALIFORNIANCT03013998

Study of Biomarker-Based Treatment of Acute Myeloid Leukemia

This screening and multi-sub-study Phase 1b/2 trial will establish a method for genomic screening followed by assigning and accruing simultaneously to a multi-study "Master Protocol (BAML-16-001-M1)."...

2,000 participants
Beat AML, LLC
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RecruitingSan Francisco, CALIFORNIANCT04375033

A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder

VA-BRAVE will determine whether a 28-day long-acting injectable sub-cutaneous (in the belly area) formulation of buprenorphine at a target dose of 300mg is superior in retaining Veterans in opioid tre...

952 participants
VA Office of Research and Development
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RecruitingSan Francisco, CALIFORNIANCT06578247

Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML

This study will compare the effects of Quizartinib versus placebo in combination with chemotherapy in participants with newly diagnosed FMS-like tyrosine kinase 3 (FLT3)-internal tandem duplication (I...

700 participants
Daiichi Sankyo
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RecruitingSan Francisco, CALIFORNIANCT06323824

Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment.

The purpose of this clinical trial is to compare the effectiveness of office-based methadone with pharmacy administration and/or dispensing to office-based buprenorphine for the treatment of opioid us...

600 participants
Yale University
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RecruitingSan Francisco, CALIFORNIANCT05554406

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

This phase II MyeloMATCH treatment trial tests whether the standard approach of cytarabine and daunorubicin in comparison to the following experimental regimens works to shrink cancer in patients with...

335 participants
National Cancer Institute (NCI)
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RecruitingSan Francisco, CALIFORNIANCT05005975

Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

To evaluate the long-term safety and tolerability of oral dersimelagon....

301 participants
Mitsubishi Tanabe Pharma America Inc.
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RecruitingSan Francisco, CALIFORNIANCT06788535

Research With I-124 EVuzamitide to Elucidate Cardiac AmyLoidosis

The purpose of this Phase 3, open label, single dose imaging study is to evaluate the efficacy and safety of I-124 evuzamitide (radioactive dye) for diagnosing Cardiac Amyloidosis in participants with...

200 participants
Sharmila Dorbala
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RecruitingSan Francisco, CALIFORNIANCT06393712

A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy

The purpose of the study is to evaluate the effect of ALN-APP on measures of CAA disease progression and to characterize the safety, tolerability, and pharmacodynamics (PD) of ALN-APP in adult patient...

200 participants
Alnylam Pharmaceuticals
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RecruitingSan Francisco, CALIFORNIANCT05503264

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Satralizumab in Participants With Anti-N-methyl-D-aspartic Acid Receptor (NMDAR) or Anti-leucine-rich Glioma-inactivated 1 (LGI1) Encephalitis

The purpose of this study is to assess the efficacy, safety, PK, and PD of satralizumab in participants with NMDAR and LGI1 encephalitis....

152 participants
Hoffmann-La Roche
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RecruitingSan Francisco, CALIFORNIANCT06910358

Study of Bitopertin in Participants With EPP or XLP (APOLLO)

The goal of this clinical trial is to learn if bitopertin works and is safe to treat EPP or XLP in participants 12 years or older. The main questions it aims to answer are: * Whether bitopertin incre...

150 participants
Disc Medicine, Inc
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RecruitingSan Francisco, CALIFORNIANCT06143631

Prescription of Letrozole for Uterine Myoma

The PLUM Study is a randomized, double-blinded, 2-arm, parallel-group, placebo-controlled trial is designed to compare the efficacy of letrozole versus placebo on leiomyoma-related symptoms and qualit...

140 participants
University of California, San Francisco
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RecruitingSan Francisco, CALIFORNIANCT06307613

A Study of Efgartigimod PH20 SC Given by Prefilled Syringe in Adults With Thyroid Eye Disease

This study aims to evaluate the efficacy, safety and tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and immunogenicity of efgartigimod PH20 SC in participants with active, moderate-to-sev...

123 participants
argenx
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RecruitingSan Francisco, CALIFORNIANCT05183035

Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

A study to evaluate if the randomized addition of venetoclax to a chemotherapy backbone (fludarabine/cytarabine/gemtuzumab ozogamicin \[GO\]) improves survival of children/adolescents/young adults wit...

98 participants
PedAL BCU, LLC
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RecruitingSan Francisco, CALIFORNIANCT07081646

A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.

Open-label Phase 1b/2 study with primary objective of this study is to evaluate the safety, tolerability and efficacy of AZD0120 in participants with light chain (AL) amyloidosis....

91 participants
Alexion Pharmaceuticals, Inc.
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RecruitingSan Francisco, CALIFORNIANCT06088979

A Study to Investigate Efficacy and Safety of TOUR006 in Participants 18 to 80 Years of Age With Thyroid Eye Disease

Phase 2b trial of TOUR006 in Thyroid Eye Disease (TED) to evaluate 20mg and 50mg doses against placebo given by a subcutaneous injection every eight weeks to TED patients who are in the active inflamm...

81 participants
Tourmaline Bio, Inc.
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RecruitingSan Francisco, CALIFORNIANCT02923011

Comparative Effectiveness of MRgFUS Versus CTgRFA for Osteoid Osteomas

Osteoid osteomas are painful, benign bone tumors that occur most frequently in young males between ages 10 and 20 years. The goal of the proposed study is based on the premise that MRgFUS is noninferi...

56 participants
Matthew Bucknor
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RecruitingSan Francisco, CALIFORNIANCT06978725

A Phase 2 Study of the Safety and Efficacy of Brepocitinib in Adults With Cutaneous Sarcoidosis (BEACON)

This study will evaluate the clinical safety and efficacy of oral brepocitinib in participants with cutaneous sarcoidosis....

28 participants
Priovant Therapeutics, Inc.
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RecruitingSan Francisco, CALIFORNIANCT05783323

Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

Papillary thyroid cancer (PTC) is the most common form of differentiated thyroid cancer (DTC). The traditional first line treatment for patients with advanced DTC after surgical resection is radioacti...

13 participants
Children's Hospital of Philadelphia
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About Osteogenesis Imperfecta Clinical Trials in San Francisco

Osteogenesis imperfecta is a group of genetic disorders mainly affecting the bones, causing them to break easily, often from little or no apparent cause. It is caused by defects in collagen production. Treatment includes bisphosphonates, physical therapy, and surgical rodding.

There are currently 18 osteogenesis imperfecta clinical trials recruiting participants in San Francisco, CALIFORNIA. These studies are seeking a combined 6,220 participants. Research is being sponsored by Beat AML, LLC, VA Office of Research and Development, Daiichi Sankyo and 15 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Osteogenesis Imperfecta Clinical Trials in San Francisco — FAQ

Are there osteogenesis imperfecta clinical trials in San Francisco?

Yes, there are 18 osteogenesis imperfecta clinical trials currently recruiting in San Francisco, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in San Francisco?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the San Francisco research site will contact you about next steps.

Are clinical trials in San Francisco free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many San Francisco studies also compensate for your time and travel.

What osteogenesis imperfecta treatments are being tested?

The 18 active trials in San Francisco are testing new therapies including novel drugs, biologics, and treatment approaches for osteogenesis imperfecta.

Data updated March 2, 2026 from ClinicalTrials.gov