NCT04662918 · Xingshun Qi
Validation of CAGIB Score for In-hospital Mortality of Cirrhotic Patients With Acute Gastrointestinal Bleeding
What this study is about
Acute gastrointestinal bleeding is potentially lethal in liver cirrhosis. Accurate assessment of prognosis is critical in a timely fashion. A novel model, CAGIB score, has been developed based on our Chinese conducted at multiple hospitals reviewing past data study.
View original scientific description
Acute gastrointestinal bleeding is potentially lethal in liver cirrhosis. Accurate assessment of prognosis is critical in a timely fashion. A novel model, CAGIB score, has been developed based on our Chinese multicenter retrospective study. Now, a prospective, international multicenter, observational study will be performed to further compare the performance of CAGIB versus Child-Pugh and MELD scores for evaluating the in-hospital mortality of patients with liver cirrhosis and acute gastrointestinal bleeding.
Primary outcome measures
Mortality
Time frame: An average of 1-6 weeks, from admission to discharge
Death caused by any events during hospitalizations.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Patients with liver cirrhosis;
- Patients with acute gastrointestinal bleeding presenting with hematemesis, melena, and/or hematochezia;
- Adults (age≥18 years old).
Exclusion criteria
- Components of Child-Pugh, MELD, and CAGIB scores are not available;
- In-hospital outcomes are not evaluable.
Where
- Scranton, Pennsylvania
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Frequently asked questions
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Data: ClinicalTrials.gov · synced Oct 7, 2025 · Source of record for eligibility and locations