Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Tuberous Sclerosis Clinical Trials
Tuberous Sclerosis clinical trials are recruiting across 19 cities. Here are the cities with the most active studies:
Tuberous Sclerosis Trial Phases
6 research organizations are sponsoring tuberous sclerosis trials.
About Tuberous Sclerosis
Tuberous sclerosis complex is a rare genetic disease that causes non-cancerous tumors to grow in many parts of the body including the brain, kidneys, heart, and skin. Symptoms vary widely depending on tumor location. Treatment includes mTOR inhibitors and management of specific symptoms.
Clinical trials are advancing new treatments for tuberous sclerosis. Currently, 6 studies are recruiting a combined 5,899 participants across the United States. Research is being conducted by 6 organizations including National Tuberous Sclerosis Association, National Heart, Lung, and Blood Institute (NHLBI), David M. Ritter and 3 others.
2026 Tuberous Sclerosis Research Landscape
As of July 2026, the tuberous sclerosis clinical trial landscape includes 6 actively recruiting studies across 19 cities in the United States. These studies are collectively seeking 5,899 participants, with an average enrollment target of 983 per study.
The research spans multiple phases of development: 2 studies are in NA, 1 study is in PHASE2.
Research is being led by 6 different organizations, including National Tuberous Sclerosis Association, National Heart, Lung, and Blood Institute (NHLBI), David M. Ritter, Children's Hospital Medical Center, Cincinnati, Darcy Krueger, and 1 others.
Geographically, tuberous sclerosis trials are most concentrated in Cincinnati, Ohio (3 trials); Birmingham, Alabama (2 trials); Los Angeles, California (2 trials); Chicago, Illinois (2 trials); Boston, Massachusetts (2 trials) and 7 other cities.
Featured Tuberous Sclerosis Studies
Highlighted recruiting studies for tuberous sclerosis, selected by enrollment size and research scope.
TSC Biosample Repository and Natural History Database
The TSC Biosample Repository collects and stores samples of blood, DNA, and tissues that scientists can request to use in their research. The samples we collect are all linked to clinical data in the TSC Natural History Database. The TSC Natural History Database captures clinical data to document the impact of the disease on a person's health over his or her lifetime. This data may be collected re...
Study of Skin Tumors in Tuberous Sclerosis
Tuberous sclerosis is a rare, hereditary disease in which patients develop multiple tumors. Although not cancerous, the tumors can affect various organs, including the heart, lungs, kidneys, skin, and central nervous system, with serious medical consequences. The severity of disease varies greatly among patients, from barely detectable to fatal. This study will investigate what causes skin tumors ...
Tuberous Sclerosis Complex and Lymphangioleiomyomatosis Pregnancy Registry (TSC-LAM Registry)
This study is an observational registry designed to gather information about Tuberous Sclerosis Complex (TSC) and Lymphangioleiomyomatosis (LAM) in pregnant women and their child.
Frequently Asked Questions About Tuberous Sclerosis Clinical Trials
Are there tuberous sclerosis clinical trials near me?
Yes, there are 6 tuberous sclerosis clinical trials currently recruiting across 19+ cities in the United States, including Cincinnati, Ohio; Birmingham, Alabama; Los Angeles, California. Browse the studies above to find one at a location convenient for you.
How do I join a tuberous sclerosis clinical trial?
To join a tuberous sclerosis clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are tuberous sclerosis clinical trials free?
Yes, participation in tuberous sclerosis clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of tuberous sclerosis treatments are being studied?
Current tuberous sclerosis clinical trials are testing a range of approaches across NA (2 studies), PHASE2 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 6 research organizations.
Is it safe to participate in tuberous sclerosis clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 16, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 16, 2026 · Data from ClinicalTrials.gov