Role of Oxidative Stress and Inflammation in Type 1 Gaucher Disease (GD1)
The purpose of this study is to measure levels of blood and brain chemicals related to oxidative stress and inflammation in healthy volunteers and individuals with Type 1 Gaucher disease (GD1) to see ...
A Clinical Trial of PR001 (LY3884961) in Patients With Peripheral Manifestations of Gaucher Disease (PROCEED)
Study J3Z-MC-OJAE is a Phase 1/2, multicenter, open-label, dose-finding study of LY3884961 evaluating the safety and tolerability in adults with peripheral manifestations of GD. Up to 3 dose levels o...
Top Cities for Gaucher Disease Clinical Trials
Gaucher Disease clinical trials are recruiting across 10 cities. Here are the cities with the most active studies:
About Gaucher Disease
Gaucher disease is an inherited metabolic disorder caused by deficiency of the enzyme glucocerebrosidase, leading to accumulation of fatty substances in organs. It is the most common lysosomal storage disorder. Treatment includes enzyme replacement therapy and substrate reduction therapy.
Clinical trials are advancing new treatments for gaucher disease. Currently, 2 studies are recruiting a combined 65 participants across the United States. Research is being conducted by 2 organizations including University of Minnesota, Prevail Therapeutics.
2026 Gaucher Disease Research Landscape
As of March 2026, the gaucher disease clinical trial landscape includes 2 actively recruiting studies across 10 cities in the United States. These studies are collectively seeking 65 participants, with an average enrollment target of 33 per study.
Research is being led by 2 different organizations, including University of Minnesota, Prevail Therapeutics.
Geographically, gaucher disease trials are most concentrated in Minneapolis, Minnesota (1 trial); New York, New York (1 trial); Chicago, Illinois (1 trial); Durham, North Carolina (1 trial); Fairfax, Virginia (1 trial) and 5 other cities.
Featured Gaucher Disease Studies
Highlighted recruiting studies for gaucher disease, selected by enrollment size and research scope.
Role of Oxidative Stress and Inflammation in Type 1 Gaucher Disease (GD1)
The purpose of this study is to measure levels of blood and brain chemicals related to oxidative stress and inflammation in healthy volunteers and individuals with Type 1 Gaucher disease (GD1) to see if these levels are altered by GD1.
A Clinical Trial of PR001 (LY3884961) in Patients With Peripheral Manifestations of Gaucher Disease (PROCEED)
Study J3Z-MC-OJAE is a Phase 1/2, multicenter, open-label, dose-finding study of LY3884961 evaluating the safety and tolerability in adults with peripheral manifestations of GD. Up to 3 dose levels of LY3884961 will be assessed in 3 dose-finding cohorts of 3 patients. Following this, up to 6 patients may be enrolled in an expansion cohort. For each enrolled patient, the study will be approximate...
Frequently Asked Questions About Gaucher Disease Clinical Trials
Are there gaucher disease clinical trials near me?
Yes, there are 2 gaucher disease clinical trials currently recruiting across 10+ cities in the United States, including Minneapolis, Minnesota; New York, New York; Chicago, Illinois. Browse the studies above to find one at a location convenient for you.
How do I join a gaucher disease clinical trial?
To join a gaucher disease clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are gaucher disease clinical trials free?
Yes, participation in gaucher disease clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of gaucher disease treatments are being studied?
Current gaucher disease clinical trials are testing a range of approaches. These include new drugs, combination therapies, medical devices, and other interventions sponsored by 2 research organizations.
Is it safe to participate in gaucher disease clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated March 1, 2026 from ClinicalTrials.gov
About This Data
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated March 1, 2026 · Data from ClinicalTrials.gov