Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Hereditary Angioedema Clinical Trials
Hereditary Angioedema clinical trials are recruiting across 47 cities. Here are the cities with the most active studies:
Hereditary Angioedema Trial Phases
12 research organizations are sponsoring hereditary angioedema trials.
About Hereditary Angioedema
Hereditary angioedema (HAE) is a rare genetic condition causing recurrent episodes of severe swelling in various body parts. It is caused by deficiency or dysfunction of C1 inhibitor protein. Treatment includes on-demand therapy for attacks and prophylactic medications to prevent episodes.
Clinical trials are advancing new treatments for hereditary angioedema. Currently, 14 studies are recruiting a combined 5,101 participants across the United States. Research is being conducted by 12 organizations including Myasthenia Gravis Foundation of America, University of Wisconsin, Madison, CSL Behring and 9 others.
2026 Hereditary Angioedema Research Landscape
As of October 2026, the hereditary angioedema clinical trial landscape includes 14 actively recruiting studies across 47 cities in the United States. These studies are collectively seeking 5,101 participants, with an average enrollment target of 364 per study.
The research spans multiple phases of development: 6 studies are in PHASE3, 3 studies are in PHASE1, 1 study is in NA, 1 study is in PHASE4, 1 study is in PHASE2. The presence of Phase 3 trials indicates that some hereditary angioedema treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 12 different organizations, including Myasthenia Gravis Foundation of America, University of Wisconsin, Madison, CSL Behring, Octapharma, KalVista Pharmaceuticals, Ltd., and 7 others. The large number of sponsors reflects significant research interest and investment in hereditary angioedema treatment advancement.
Geographically, hereditary angioedema trials are most concentrated in Miami, Florida (4 trials); St Louis, Missouri (4 trials); Wheaton, Maryland (3 trials); Phoenix, Arizona (2 trials); Las Vegas, Nevada (2 trials) and 7 other cities.
Featured Hereditary Angioedema Studies
Highlighted recruiting studies for hereditary angioedema, selected by enrollment size and research scope.
Myasthenia Gravis Foundation of America Global MG Patient Registry
The goal of this observational study is to learn about the experiences of people living with Myasthenia Gravis (MG) in the United States. The main questions it aims to answer are: * How and when are people with MG diagnosed? * What are the most common symptoms associated with MG? * What treatments are being used to treat MG? * What are the impacts of MG on activities of daily living, employment a...
Healing Tiny Minds: Rural Recovery Through Virtual and Lived Experience Care
The goal of this behavioral-interventional study is to learn if the Abecedarian Approach implemented virtually for children ages 0-5 with a history of Hypoxic Ischaemic Encephalopathy (HIE) and/or premature birth produces the same effects as when administered at in-person facilities.
A Study Investigating the Effectiveness and Safety of Garadacimab for Treating Patients With Hereditary Angioedema (HAE)
This is a multinational, multicenter, prospective, observational cohort study of patients with HAE in the real-world setting. The study will include patients newly initiating garadacimab in routine clinical practice. Each participant will be followed for 48 months after index date (date of the first administration of garadacimab). Patient data will be collected from the HAE eDiary, patient medica...
Frequently Asked Questions About Hereditary Angioedema Clinical Trials
Are there hereditary angioedema clinical trials near me?
Yes, there are 14 hereditary angioedema clinical trials currently recruiting across 47+ cities in the United States, including Miami, Florida; St Louis, Missouri; Wheaton, Maryland. Browse the studies above to find one at a location convenient for you.
How do I join a hereditary angioedema clinical trial?
To join a hereditary angioedema clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are hereditary angioedema clinical trials free?
Yes, participation in hereditary angioedema clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of hereditary angioedema treatments are being studied?
Current hereditary angioedema clinical trials are testing a range of approaches across PHASE3 (6 studies), PHASE1 (3 studies), NA (1 study), PHASE4 (1 study), PHASE2 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 12 research organizations.
Is it safe to participate in hereditary angioedema clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated October 16, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated October 16, 2026 · Data from ClinicalTrials.gov