Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Spinal Muscular Atrophy Clinical Trials
Spinal Muscular Atrophy clinical trials are recruiting across 272 cities. Here are the cities with the most active studies:
Spinal Muscular Atrophy Trial Phases
63 research organizations are sponsoring spinal muscular atrophy trials.
About Spinal Muscular Atrophy
Spinal muscular atrophy (SMA) is a genetic neuromuscular disorder that causes loss of motor neurons, leading to progressive muscle weakness and atrophy. It is the leading genetic cause of infant death. Revolutionary gene therapies and SMN-enhancing drugs have transformed treatment.
Clinical trials are advancing new treatments for spinal muscular atrophy. Currently, 100 studies are recruiting a combined 251,804 participants across the United States. Research is being conducted by 63 organizations including University of Utah, Heart Rhythm Clinical and Research Solutions, LLC, SWOG Cancer Research Network and 60 others.
2026 Spinal Muscular Atrophy Research Landscape
As of July 2026, the spinal muscular atrophy clinical trial landscape includes 100 actively recruiting studies across 272 cities in the United States. These studies are collectively seeking 251,804 participants, with an average enrollment target of 2,518 per study.
The research spans multiple phases of development: 43 studies are in PHASE3, 23 studies are in PHASE2, 22 studies are in PHASE1, 5 studies are in NA, 1 study is in PHASE4. The presence of Phase 3 trials indicates that some spinal muscular atrophy treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 63 different organizations, including University of Utah, Heart Rhythm Clinical and Research Solutions, LLC, SWOG Cancer Research Network, US Oncology Research, Ohio State University Comprehensive Cancer Center, and 58 others. The large number of sponsors reflects significant research interest and investment in spinal muscular atrophy treatment advancement.
Geographically, spinal muscular atrophy trials are most concentrated in Los Angeles, California (19 trials); Boston, Massachusetts (17 trials); Duarte, California (14 trials); Baltimore, Maryland (13 trials); Irvine, California (13 trials) and 7 other cities.
Featured Spinal Muscular Atrophy Studies
Highlighted recruiting studies for spinal muscular atrophy, selected by enrollment size and research scope.
Machine Learning Approaches to Personalized Therapy for Advanced Non-small Cell Lung Cancer With Real-World Data
This research will leverage machine learning (ML) and causal inference techniques applied to real-world data (RWD) to generate evidence that personalizes treatment strategies for patients with advanced non-small cell lung cancer (aNSCLC). Rather than influencing regulatory decisions or clinical guidelines, the goal of this trial is to refine treatment selection among existing therapeutic options, ...
Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias
The primary purpose of this Registry is to assess procedural safety and long-term effectiveness of catheter ablations in the treatment of subjects with PAF, PsAF, and VA. The Registry will utilize real world clinical data obtained from the use of commercially available CARTO™ technologies under the authority of a health care practitioner within a legitimate practitioner-subject relationship. Data ...
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
This screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and accruing simultaneously to a multi-sub-study hybrid Master Protocol (Lung-MAP). The type of cancer trait (biomarker) will determine to which sub-study, within this protocol, a participant will be assigned to compare new targete...
Frequently Asked Questions About Spinal Muscular Atrophy Clinical Trials
Are there spinal muscular atrophy clinical trials near me?
Yes, there are 100 spinal muscular atrophy clinical trials currently recruiting across 272+ cities in the United States, including Los Angeles, California; Boston, Massachusetts; Duarte, California. Browse the studies above to find one at a location convenient for you.
How do I join a spinal muscular atrophy clinical trial?
To join a spinal muscular atrophy clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are spinal muscular atrophy clinical trials free?
Yes, participation in spinal muscular atrophy clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of spinal muscular atrophy treatments are being studied?
Current spinal muscular atrophy clinical trials are testing a range of approaches across PHASE3 (43 studies), PHASE2 (23 studies), PHASE1 (22 studies), NA (5 studies), PHASE4 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 63 research organizations.
Is it safe to participate in spinal muscular atrophy clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 17, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 17, 2026 · Data from ClinicalTrials.gov