New Haven, CONNECTICUT13 Active Studies

Osteogenesis Imperfecta Clinical Trials in New Haven, CONNECTICUT

Find 13 actively recruiting osteogenesis imperfecta clinical trials in New Haven, CONNECTICUT. Connect with local research sites and explore new treatment options.

13
Active Trials
13
Sponsors
3,323
Enrolling

Recruiting Osteogenesis Imperfecta Studies in New Haven

RecruitingNew Haven, CONNECTICUTNCT06578247

Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML

This study will compare the effects of Quizartinib versus placebo in combination with chemotherapy in participants with newly diagnosed FMS-like tyrosine kinase 3 (FLT3)-internal tandem duplication (I...

700 participants
Daiichi Sankyo
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RecruitingNew Haven, CONNECTICUTNCT06563895

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

Transthyretin amyloidosis (ATTR) is a disease where the normally occurring transthyretin (TTR) protein falls apart and forms amyloid, a sticky plaque- like substance that accumulates in different orga...

582 participants
Eidos Therapeutics, a BridgeBio company
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RecruitingNew Haven, CONNECTICUTNCT06022939

Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

This phase III trial compares the effect of adding a stem cell transplant with melphalan after completing chemotherapy with daratumumab, cyclophosphamide, bortezomib and dexamethasone (Dara-VCD) versu...

338 participants
SWOG Cancer Research Network
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RecruitingNew Haven, CONNECTICUTNCT06475989

Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

This phase III trial compares the effect of cabozantinib versus combination dabrafenib and trametinib for the treatment of patients with differentiated thyroid cancer that does not respond to treatmen...

264 participants
ECOG-ACRIN Cancer Research Group
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RecruitingNew Haven, CONNECTICUTNCT03850574

Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia

The main purpose of this study is to identify a safe and potentially effective dose of tuspetinib to be used in future studies in study participants diagnosed with acute myeloid leukemia (AML), myelod...

240 participants
Aptose Biosciences Inc.
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RecruitingNew Haven, CONNECTICUTNCT04256317

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

Study ASTX030-01 is a multi-phase study comprising of Phases 1-3 Monotherapy arms and a Phase 1 Combination Therapy arm Phase 1 Monotherapy consists of an open-label Dose Escalation Stage (Stage A) us...

236 participants
Taiho Oncology, Inc.
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RecruitingNew Haven, CONNECTICUTNCT06788535

Research With I-124 EVuzamitide to Elucidate Cardiac AmyLoidosis

The purpose of this Phase 3, open label, single dose imaging study is to evaluate the efficacy and safety of I-124 evuzamitide (radioactive dye) for diagnosing Cardiac Amyloidosis in participants with...

200 participants
Sharmila Dorbala
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RecruitingNew Haven, CONNECTICUTNCT03593759

Cardiac Sarcoidosis Randomized Trial

Prospective randomized controlled trial comparing low dose Prednisone(or Prednisolone)/Methotrexate combination to standard dose Prednisone(or Prednisolone) in patients diagnosed with acute active cli...

194 participants
Ottawa Heart Institute Research Corporation
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RecruitingNew Haven, CONNECTICUTNCT06864169

A Study of Raludotatug Deruxtecan (R-DXd) in People With Gastrointestinal Cancers (MK-5909-005)

Researchers are looking for new ways to treat certain types of advanced gastrointestinal (GI) cancers. The study medicine raludotatug deruxtecan (also called MK-5909, R-DXd, or DS-6000a) is a type of ...

160 participants
Merck Sharp & Dohme LLC
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RecruitingNew Haven, CONNECTICUTNCT07087054

Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen

A Phase 3, randomized, double-blinded, placebo-controlled study to evaluate the efficacy and safety of paltusotine treatment vs placebo as well as the long-term safety of paltusotine in adults with ca...

141 participants
Crinetics Pharmaceuticals Inc.
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RecruitingNew Haven, CONNECTICUTNCT06384261

A Study Comparing Venetoclax and Azacitidine Plus Cusatuzumab to Venetoclax and Azacitidine in Newly Diagnosed AML Ineligible for Intensive Therapy

The goal of this clinical trial is to learn if participants treated with the experimental drug cusatuzumab added to venetoclax and azacitidine works to treat acute myeloid leukemia (AML) compared to v...

120 participants
OncoVerity, Inc.
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RecruitingNew Haven, CONNECTICUTNCT05183035

Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

A study to evaluate if the randomized addition of venetoclax to a chemotherapy backbone (fludarabine/cytarabine/gemtuzumab ozogamicin \[GO\]) improves survival of children/adolescents/young adults wit...

98 participants
PedAL BCU, LLC
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RecruitingNew Haven, CONNECTICUTNCT05364008

FRIEND: Fibroids and Unexplained Infertility Treatment With Epigallocatechin Gallate; A Natural CompounD in Green Tea

The objective of this study is to determine the effect of low caffeine green tea extract containing 45% epigallocatechin gallate (EGCG) on fibroids and subsequent pregnancy and live births in women se...

50 participants
Yale University
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About Osteogenesis Imperfecta Clinical Trials in New Haven

Osteogenesis imperfecta is a group of genetic disorders mainly affecting the bones, causing them to break easily, often from little or no apparent cause. It is caused by defects in collagen production. Treatment includes bisphosphonates, physical therapy, and surgical rodding.

There are currently 13 osteogenesis imperfecta clinical trials recruiting participants in New Haven, CONNECTICUT. These studies are seeking a combined 3,323 participants. Research is being sponsored by Daiichi Sankyo, Eidos Therapeutics, a BridgeBio company, SWOG Cancer Research Network and 10 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Osteogenesis Imperfecta Clinical Trials in New Haven — FAQ

Are there osteogenesis imperfecta clinical trials in New Haven?

Yes, there are 13 osteogenesis imperfecta clinical trials currently recruiting in New Haven, CONNECTICUT. Browse the studies on this page to find one that fits.

How do I join a clinical trial in New Haven?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the New Haven research site will contact you about next steps.

Are clinical trials in New Haven free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many New Haven studies also compensate for your time and travel.

What osteogenesis imperfecta treatments are being tested?

The 13 active trials in New Haven are testing new therapies including novel drugs, biologics, and treatment approaches for osteogenesis imperfecta.

Data updated March 2, 2026 from ClinicalTrials.gov