21 Stroke Clinical Trials in Baltimore, MD (2026)

Q: How do I join a clinical trial in Baltimore?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Baltimore research site will contact you.

Recruiting Stroke Studies in Baltimore

NCT04916210Recruiting

Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

The overall goal of the DISCOVERY study is to better understand what factors contribute to changes in cognitive (i.e., thinking and memory) abilities in patients who experienced a stroke. The purpose ...

Baltimore, MD8,000 participantsMassachusetts General Hospital

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NCT00682695Recruiting

Genetic and Environmental Risk Factors for Hemorrhagic Stroke

The purpose of this study is to find risk factors for hemorrhagic stroke....

Baltimore, MD1,000 participantsState University of New York at Buffalo

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NCT07491952Recruiting

Continuous Dual Aspiration Technique With Zoom System for Stroke

This study is designed to evaluate the effectiveness, safety and clinical performance of ADAPT 2.0, first-line aspiration neurothrombectomy with Zoom System with Continuous Dual Aspiration Technique (...

Baltimore, MD750 participantsImperative Care, Inc.

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NCT06990867Recruiting

Optimizing Reperfusion to Improve Outcomes and Neurologic Function

The goal of this study is to evaluate the safety and efficacy of JX10 versus placebo in participants with Acute Ischemic Stroke (AIS) who present for care within 4.5 to 24 hours. The main question th...

Baltimore, MDPHASE2740 participantsCorxel Pharmaceuticals

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NCT05701280Recruiting

Pilot/Pivotal Study of DBS+Rehab After Stroke

The RESTORE Stroke Study will evaluate the safety and effectiveness of DBS+Rehab for treating arm weakness and reduced function after a stroke....

Baltimore, MDNA202 participantsEnspire DBS Therapy, Inc.

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NCT05556395Recruiting

Global Blood-Brain Barrier Disruption and Post-Stroke Cognitive Decline

The goal of this study is to gain a better understanding of why some individuals who have suffered a stroke experience post-stroke cognitive decline. Specifically this study is testing whether global ...

Baltimore, MD150 participantsJohns Hopkins University

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NCT02369770Recruiting

Sensory-Motor Rehabilitation Post Stroke

Early after stroke, patients often have significant motor impairment and sensory deficit. Evidence has demonstrated heightened plasticity and significant recovery in the acute phase (first months) pos...

Baltimore, MDNA140 participantsUniversity of Maryland, Baltimore

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NCT06440707Recruiting

Transcranial Direct Current Stimulation for Treatment of Acute Ischemic Stroke

Many patients with acute ischemic stroke are ineligible for currently available standard treatments (clot-busting medication, also known as intravenous thrombolytic or mechanical removal of a clot), a...

Baltimore, MDPHASE2120 participantsUniversity of California, Los Angeles

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NCT05563038Recruiting

Scrambler Therapy for Post-Stroke Pain

The Investigators will enroll patients who have had a stroke and are experiencing post-stroke pain secondary to their infarct and disruption of the sensory system in a research study to compare the ef...

Baltimore, MDNA100 participantsJohns Hopkins University

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NCT02359253Recruiting

Robot Aided Rehabilitation - Intervention

Sensorimotor impairments following stroke often involve complex pathological changes across multiple joints and multiple degrees of freedom of the arm and hand, thereby rendering them difficult to dia...

Baltimore, MDNA72 participantsUniversity of Maryland, Baltimore

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NCT06718413Recruiting

Myofascial Dysfunction in Post Stroke Shoulder Pain

Shoulder pain is extremely common after stroke and occurs in 30-70% of patients. The pain may begin as early as one week after stroke, although peak onset and severity occurs around four months, and p...

Baltimore, MDPHASE268 participantsJohns Hopkins University

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NCT06404268Recruiting

Facilitating Neuroplastic Changes of Acute Stroke Survivors

This project will develop a wearable rehabilitation robot suitable for in-bed acute stage rehabilitation. It involves robot-guided motor relearning, passive and active motor-sensory rehabilitation ear...

Baltimore, MDPHASE168 participantsUniversity of Maryland, Baltimore

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NCT05093673Recruiting

Cerebellar Stimulation for Aphasia Rehabilitation

The optimal site of neuromodulation for post-stroke aphasia has yet to be established. This study will investigate whether multiple sessions of cerebellar transcranial direct current stimulation (tDCS...

Baltimore, MDNA60 participantsJohns Hopkins University

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NCT04550728Recruiting

Hybrid Robot+FES Stroke Rehabilitation

The investigators have developed a novel robot-guided stretching under intelligent control and combine it with active movement training, which helped increase joint ROM, reduce spasticity and joint st...

Baltimore, MDPHASE160 participantsUniversity of Maryland, Baltimore

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NCT05929027Recruiting

Self-Administered Gaming and Exercise at Home (SAGEH)

This study aims at comparing manual function outcomes between the standard of care and additional self-administered hand therapy after stroke. Strokes are common neurological injuries, and although ra...

Baltimore, MDNA60 participantsJohns Hopkins University

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NCT05195398Recruiting

TDCS to Improve Post-Stroke Cognitive Impairment

The investigators will conduct a randomized, double-blinded, sham-controlled trial of approximately 60 patients with minor stroke and post-stroke mild cognitive impairment (psMCI). Participants will b...

Baltimore, MDNA60 participantsJohns Hopkins University

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NCT02359812Recruiting

Robot Aided Rehabilitation - Multi-joint Evaluations

Sensory and motor impairments following stroke can lead to substantial disability involving the arm and hand. The investigator hypothesized that excessive local and cross-coupled stiffness, diminished...

Baltimore, MD56 participantsUniversity of Maryland, Baltimore

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NCT04188522Recruiting

Imaging Post-Stroke Recovery: Using MEG to Evaluate Cognition

This is a study using magnetoencephalography (MEG) to look at recovery in those with minor stroke. The investigators know that these individuals report difficulties in attention, concentration, multi-...

Baltimore, MD55 participantsJohns Hopkins University

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NCT05703386Recruiting

Imaging the Pathogenesis of Cerebral Small Vessel Disease

Cerebral small vessel disease (CSVD) can lead to vascular cognitive impairment and dementia (VCID). The hallmark of CSVD is the appearance and progression of white matter hyperintensities (WMH) on MRI...

Baltimore, MD50 participantsJohns Hopkins University

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NCT07053917Recruiting

Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability

The main purpose of the current studies is to evaluate the safety and tolerability of psilocybin in patients with chronic stroke....

Baltimore, MDPHASE120 participantsJohns Hopkins University

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NCT07209488Recruiting

Acquired Dyslexia Modeling and Treatment

This study is a low-risk, early phase 1, multicenter trial to test the use of a computational (neural network) cognitive model of reading to simulate acquired dyslexia and its treatment. The aim is to...

Baltimore, MDNA12 participantsRutgers, The State University of New Jersey

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About Stroke Clinical Trials in Baltimore

A stroke occurs when blood flow to part of the brain is interrupted or reduced, depriving brain tissue of oxygen and nutrients. It is a leading cause of disability and death. Rapid treatment is critical, and prevention focuses on managing risk factors like hypertension and atrial fibrillation.

There are currently 21 stroke clinical trials recruiting participants in Baltimore, MD. These studies are seeking a combined 11,843 participants. Research is being sponsored by Massachusetts General Hospital, State University of New York at Buffalo, Imperative Care, Inc. and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Stroke Clinical Trials in Baltimore — FAQ

Are there stroke clinical trials in Baltimore?

Yes, there are 21 stroke clinical trials currently recruiting in Baltimore, MD. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Baltimore?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Baltimore research site will contact you about next steps.

Are clinical trials in Baltimore free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Baltimore studies also compensate for your time and travel.

What stroke treatments are being tested?

The 21 active trials in Baltimore are testing new therapies including novel drugs, biologics, and treatment approaches for stroke.

Data updated July 18, 2026 from ClinicalTrials.gov