Bethesda, MD6 Active Studies

Advanced Solid Tumors Clinical Trials in Bethesda, MD

Find 6 actively recruiting advanced solid tumors clinical trials in Bethesda, MD. Connect with local research sites and explore new treatment options.

6
Active Trials
5
Sponsors
10,802
Enrolling

Recruiting Advanced Solid Tumors Studies in Bethesda

NCT03739827Recruiting

Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

Background: Approximately 150 cases of cancer per one million per year are considered rare cancers. While all tumors originate from genetic changes, a small percentage of these tumors are familial. R...

Bethesda, MD10,000 participantsNational Cancer Institute (NCI)
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NCT05592626Recruiting

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

This is an open label, multicenter, phase 1/2 study to assess the safety/tolerability and preliminary clinical activity of STAR0602 as a single agent administered intravenously in participants with ad...

Bethesda, MDPHASE1365 participantsMarengo Therapeutics, Inc.
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NCT05270213Recruiting

Evaluation of RBS2418 in Subjects With Advanced, Metastatic Solid Tumors

RBS2418 (investigational product) is a specific immune modulator, working through ectonucleotide pyrophosphatase/phosphodiesterase I (ENPP1), designed to lead to anti-tumor immunity by increasing endo...

Bethesda, MDPHASE1164 participantsRiboscience, LLC.
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NCT04222413Recruiting

Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

Background: Metastasis is the spread of cancer from one organ to a nonadjacent organ. It causes 90% of cancer deaths. No treatment specifically prevents or reduces metastasis. Researchers hope a new ...

Bethesda, MDPHASE1116 participantsNational Cancer Institute (NCI)
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NCT06171750Recruiting

Phase I Study of Tolododekin Alfa (ANK-101) in Advanced Solid Tumors

This is a Phase 1, multicenter, open-label dose escalation study to determine the safety and tolerability of intratumoral (IT) injection of tolododekin alfa (ANK-101) in participants with advanced sol...

Bethesda, MDPHASE197 participantsAnkyra Therapeutics, Inc
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NCT06258304Recruiting

A Dose Escalation and Expansion Study of GIGA-564 in Participants With Locally Advanced or Metastatic Solid Tumor Malignancies

The purpose of this study is to assess the safety and tolerability of GIGA-564 and identify the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D) level(s) of GIGA-564 in participants wi...

Bethesda, MDPHASE160 participantsGigaGen, Inc.
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About Advanced Solid Tumors Clinical Trials in Bethesda

Advanced solid tumors refer to cancers that have grown beyond the original site or spread to distant organs. Many clinical trials enroll patients with various types of advanced solid tumors to test novel therapies. These trials often investigate immunotherapy, targeted therapy, and combination approaches.

There are currently 6 advanced solid tumors clinical trials recruiting participants in Bethesda, MD. These studies are seeking a combined 10,802 participants. Research is being sponsored by National Cancer Institute (NCI), Marengo Therapeutics, Inc., Riboscience, LLC. and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Advanced Solid Tumors Clinical Trials in Bethesda — FAQ

Are there advanced solid tumors clinical trials in Bethesda?

Yes, there are 6 advanced solid tumors clinical trials currently recruiting in Bethesda, MD. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Bethesda?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Bethesda research site will contact you about next steps.

Are clinical trials in Bethesda free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Bethesda studies also compensate for your time and travel.

What advanced solid tumors treatments are being tested?

The 6 active trials in Bethesda are testing new therapies including novel drugs, biologics, and treatment approaches for advanced solid tumors.

Data updated July 17, 2026 from ClinicalTrials.gov