11 Sarcoma Clinical Trials in Bethesda, MD (2026)

Q: How do I join a clinical trial in Bethesda?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Bethesda research site will contact you.

Recruiting Sarcoma Studies in Bethesda

NCT01109394Recruiting

Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies

Background: \- Laboratory investigators who are studying common childhood cancers are interested in developing a tissue repository to collect and store blood, serum, tissue, urine, or tumors of child...

Bethesda, MD6,035 participantsNational Cancer Institute (NCI)

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NCT06503146Recruiting

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

Background: Fibroblast-activation protein (FAP) is an enzyme that appears in high numbers in cancer-associated fibroblasts of certain cancer types. \[18F\]FAPI-74 is a new PET (positron emission tomo...

Bethesda, MDPHASE2320 participantsNational Cancer Institute (NCI)

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NCT06375122Recruiting

Natural History Study of Kaposi Sarcoma

Background: Kaposi sarcoma (KS) is a type of tumor caused by the Kaposi sarcoma herpesvirus. KS usually affects the skin, but lesions can also appear in the lymph nodes, lungs and digestive tract. KS...

Bethesda, MD150 participantsNational Cancer Institute (NCI)

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NCT04941274Recruiting

Abemaciclib in Patients With HIV-associated and HIV-negative Kaposi Sarcoma

Background: Kaposi Sarcoma (KS) is common in people with human immunodeficiency virus (HIV) but can also occur in people who do not have HIV. KS tumors usually involve the skin, but may also involve ...

Bethesda, MDPHASE1111 participantsNational Cancer Institute (NCI)

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NCT04303117Recruiting

PDS01ADC Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma

Background: Kaposi sarcoma (KS) tumors grow on the skin, lymph nodes, lungs, bone, and gastrointestinal tract. KS often affects people with immune deficiencies, such as among people living with HIV o...

Bethesda, MDPHASE180 participantsNational Cancer Institute (NCI)

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NCT07308886Recruiting

Recombinant Glycosylated Human Interleukin-7 (CYT107) for the Treatment of Kaposi Sarcoma in Participants With HIV and Immune Non-Response (REGIMENKS HIV)

Background: Kaposi sarcoma (KS) is a cancer that causes abnormal tissue to grow in the skin, lymph nodes, and other organs. KS is caused by a virus known as Kaposi sarcoma herpesvirus. People infecte...

Bethesda, MDPHASE255 participantsNational Cancer Institute (NCI)

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NCT06865664Recruiting

FGFR4 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory Rhabdomyosarcoma

Background: Rhabdomyosarcoma (RMS) is a cancer of soft tissues. It is the most common soft tissue sarcoma seen in children. RMS cancer cells have a protein called FGFR4 on their surface. Researchers ...

Bethesda, MDPHASE150 participantsNational Cancer Institute (NCI)

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NCT06176989Recruiting

Enasidenib in IDH2-Mutated Malignant Sinonasal and Skull Base Tumors

Background: Cancers of the nasal cavity or skull base are rare. They often are not diagnosed until they are at an advanced stage, and they often spread to other parts of the body. These cancers may h...

Bethesda, MDPHASE240 participantsNational Cancer Institute (NCI)

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NCT06066138Recruiting

A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing

Background: A type of drug called monoclonal antibody immune checkpoint inhibitors are often used in cancer treatment. These drugs help the body s immune system fight cancer by blocking proteins that...

Bethesda, MDPHASE130 participantsNational Cancer Institute (NCI)

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NCT05711615Recruiting

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

This phase I trial tests the safety, side effects, and best dose of combination therapy with liposomal doxorubicin and peposertib in treating patients with sarcoma that has spread from where it first ...

Bethesda, MDPHASE130 participantsNational Cancer Institute (NCI)

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NCT05333458Recruiting

Testing Atezolizumab With Selinexor in People ≥ 12 Years Old With Alveolar Soft Part Sarcoma, The AXIOM Trial

This phase II trial tests whether atezolizumab in combination with selinexor works to shrink tumors in patients with alveolar soft part sarcoma and whether the study drugs are better than the usual ap...

Bethesda, MDPHASE227 participantsNational Cancer Institute (NCI)

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About Sarcoma Clinical Trials in Bethesda

Sarcomas are rare cancers that arise in bone and soft tissues including muscle, fat, blood vessels, and connective tissue. There are more than 70 subtypes of sarcoma. Treatment usually involves surgery combined with radiation and/or chemotherapy.

There are currently 11 sarcoma clinical trials recruiting participants in Bethesda, MD. These studies are seeking a combined 6,928 participants. Research is being sponsored by National Cancer Institute (NCI). Clinical trial participation is free and participants receive study-related medical care at no cost.

Sarcoma Clinical Trials in Bethesda — FAQ

Are there sarcoma clinical trials in Bethesda?

Yes, there are 11 sarcoma clinical trials currently recruiting in Bethesda, MD. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Bethesda?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Bethesda research site will contact you about next steps.

Are clinical trials in Bethesda free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Bethesda studies also compensate for your time and travel.

What sarcoma treatments are being tested?

The 11 active trials in Bethesda are testing new therapies including novel drugs, biologics, and treatment approaches for sarcoma.

Data updated July 18, 2026 from ClinicalTrials.gov