19 COPD Clinical Trials in Birmingham, AL (2026)

Q: How do I join a clinical trial in Birmingham?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Birmingham research site will contact you.

Recruiting COPD Studies in Birmingham

NCT04543461Recruiting

American Lung Association (ALA) Lung Health Cohort

The ALA-LHC is a longitudinal, multi-center cohort study that will enroll approximately 4,000 young adults between the ages of 25-35 who do not have severe lung disease. The overarching objective of t...

Birmingham, AL4,000 participantsJohns Hopkins University

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NCT01915511Recruiting

Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry

The Idiopathic Pulmonary Fibrosis Prospective Outcomes (IPF-PRO) Registry started recruiting in 2014 with the objective of studying Idiopathic Pulmonary Fibrosis. In 2018, the registry expanded to inc...

Birmingham, AL3,000 participantsDuke University

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NCT05878769Recruiting

A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)

The purpose of this study is to assess the long-term safety and to explore the efficacy of astegolimab in participants with chronic obstructive pulmonary disease (COPD) who have completed the 52-week ...

Birmingham, ALPHASE32,000 participantsHoffmann-La Roche

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NCT07363694Recruiting

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease

The purpose of this clinical trial is to learn about the effects and safety of the study medicine PF-07275315 for the potential treatment of COPD. COPD is a condition that makes it difficult to breath...

Birmingham, ALPHASE21,156 participantsPfizer

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NCT05033990Recruiting

SPIROMICS Study of Early COPD Progression (SOURCE)

This is an observational study of 1000 participants to further define the nature of early chronic obstructive pulmonary disease (COPD) in younger, at-risk individuals. The study has three main goals:...

Birmingham, AL1,000 participantsUniversity of Massachusetts, Worcester

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NCT06177717Recruiting

Deep Functional Phenotyping of the ALA Lung Health Cohort

The goal of this observational study is to learn about lung structure and function in a group of 1000 healthy people aged 25 to 35. The main questions it aims to answer are whether people's bodies, en...

Birmingham, AL1,000 participantsJohns Hopkins University

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NCT07082738Recruiting

A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

This Phase IIb dose-ranging study will evaluate the efficacy and safety of 3 different doses of AZD6793 compared with placebo tablets in participants with moderate to very severe chronic obstructive p...

Birmingham, ALPHASE2987 participantsAstraZeneca

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NCT07190222Recruiting

Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype

This is a parallel, Phase 2b/Phase 3, 3-arm study to investigate the efficacy, safety, and tolerability of subcutaneous (SC) treatment with lunsekimig compared with placebo in adult participants (aged...

Birmingham, ALPHASE3942 participantsSanofi

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NCT06388421Recruiting

DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

This is a prospective, real world, multicenter, registry of patients with pulmonary hypertension associated with interstitial lung disease (PH-ILD) and interstitial lung disease (ILD)....

Birmingham, AL900 participantsUnited Therapeutics

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NCT06376994Recruiting

Multi-Center Clean Air Randomized Controlled Trial in COPD

This is a multi-center randomized, sham-controlled clinical trial to determine the effectiveness of an air cleaner intervention aimed at improving indoor air quality on reducing COPD exacerbation risk...

Birmingham, ALPHASE3770 participantsJHSPH Center for Clinical Trials

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NCT05204888Recruiting

myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home

Parallel-group, prospective, randomized, controlled phase III trial of home High flow Nasal Therapy (HFNT) via myAirvo 3 plus usual COPD medical care vs. usual COPD medical care, for at least 1 year a...

Birmingham, ALNA642 participantsTemple University

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NCT06925373Recruiting

Housing, Environment, And Living Conditions for Transformed Health

This project will compare the health effects of public housing renovation, neighborhood built and social environment improvements, and indoor air purification, alone and in combination, as well as the...

Birmingham, ALNA460 participantsUniversity of Alabama at Birmingham

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NCT07059091Recruiting

Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

This research is being done to test if a drug called omalizumab can help people with Chronic Obstructive Pulmonary Disease (COPD) and allergies. Each participant will be in the study for about 16 mon...

Birmingham, ALPHASE2334 participantsJohns Hopkins University

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NCT06891755Recruiting

Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

The objective of this study is to assess the safety and efficacy of Apreo BREATHE system when used to support native airways and release trapped air in the treatment of adult COPD patients with emphys...

Birmingham, ALNA250 participantsApreo Health, Inc.

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NCT07053423Recruiting

A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.

LPS18583 is a multinational, randomized, double-blind, placebo-controlled, parallel-group, Phase 4 study with 2 treatment groups. The purpose of this study is to assess the effect of dupilumab compare...

Birmingham, ALPHASE4218 participantsSanofi

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NCT07051707Recruiting

Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD

The dNerva Lung Denervation System is one-time treatment intended to improve breathing in Chronic Obstructive Pulmonary Disease (COPD) patients on standard medical care. The purpose of this study is t...

Birmingham, ALNA200 participantsNuvaira, Inc.

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NCT06496620Recruiting

A Study to Evaluate Solrikitug in Participants With COPD (ZION)

A Randomized, Double-blind, Placebo-controlled, Multiple Dose-Ranging Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Solrikitug in Participants with Chronic Obstru...

Birmingham, ALPHASE2171 participantsUniquity One (UNI)

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NCT07222410Recruiting

Closed Loop Oxygen Control in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Nasal High Flow in the Hospital

The trial aims to evaluate whether the Airvo 3 device in OptiO2 mode can maintain patients' SpO2 levels within the target range better than manual oxygen titration in hospitalized COPD patients with h...

Birmingham, ALNA70 participantsFisher and Paykel Healthcare

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NCT05270525Recruiting

Effect of Ensifentrine on Sputum Markers of Inflammation in COPD

This is a randomized, double-blind, placebo-controlled, two-period cross-over study of nebulized ensifentrine (3 mg) or placebo administered BID for two 8-week Treatment Periods. All participants with...

Birmingham, ALPHASE256 participantsVerona Pharma plc

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About COPD Clinical Trials in Birmingham

Chronic obstructive pulmonary disease (COPD) is a progressive lung disease that makes breathing difficult, primarily caused by smoking. It includes emphysema and chronic bronchitis. Treatment involves bronchodilators, inhaled steroids, pulmonary rehabilitation, and oxygen therapy.

There are currently 19 copd clinical trials recruiting participants in Birmingham, AL. These studies are seeking a combined 18,156 participants. Research is being sponsored by Johns Hopkins University, Duke University, Hoffmann-La Roche and 13 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

COPD Clinical Trials in Birmingham — FAQ

Are there copd clinical trials in Birmingham?

Yes, there are 19 copd clinical trials currently recruiting in Birmingham, AL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Birmingham?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Birmingham research site will contact you about next steps.

Are clinical trials in Birmingham free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Birmingham studies also compensate for your time and travel.

What copd treatments are being tested?

The 19 active trials in Birmingham are testing new therapies including novel drugs, biologics, and treatment approaches for copd.

Data updated July 18, 2026 from ClinicalTrials.gov