16 HIV AIDS Clinical Trials in Birmingham, AL (2026)

Q: How do I join a clinical trial in Birmingham?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Birmingham research site will contact you.

Recruiting HIV AIDS Studies in Birmingham

NCT07044297Recruiting

A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)

Researchers are looking for new medicines to prevent HIV-1 (Human Immunodeficiency Virus Type 1) infection. The goals of this study are to learn: * If taking MK-8527 once a month works to prevent HI...

Birmingham, ALPHASE34,390 participantsMerck Sharp & Dohme LLC

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NCT07473778Recruiting

Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention

The goal of this observational study is to generate real-life information on the use of lenacapavir (LEN, YEZTUGO®, (YTG)) for pre-exposure prophylaxis (PrEP) across diverse clinical settings in the U...

Birmingham, AL3,000 participantsGilead Sciences

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NCT05723653Recruiting

Hybrid Type I Effectiveness-Implementation Trial of a Social Network Support Intervention

The goal of this Hybrid Type I effectiveness-implementation trial is to test an evidence-based, flexible, and tailored intervention that leverages existing social network members to promote retention ...

Birmingham, ALNA900 participantsUniversity of Chicago

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NCT06694805Recruiting

A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1

This study will assess how effective, safe, and long-lasting a long-acting antiretroviral therapy (ART) using CAB LA + RPV LA is for people with HIV who still have detectable virus levels despite bein...

Birmingham, ALPHASE3332 participantsViiV Healthcare

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NCT05547048Recruiting

Integrated e-Health (Electronic Health) for HIV and Substance Use Disorders in Justice Involved Women

The purpose of this 2-site (CT, AL) study is to test innovative interventions to reduce stigma and improve the pre-exposure prophylaxis (PrEP) and opioid use disorder (OUD) care continua in women invo...

Birmingham, ALPHASE4250 participantsYale University

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NCT06812494Recruiting

A Study of VRC07-523LS, PGT121.414.LS, and PGDM1400LS Broadly Neutralizing Monoclonal Antibodies Given Intravenously in Adult Participants Without HIV

HVTN 206/HPTN 114 is a randomized, double blind, controlled, phase 2 clinical trial to evaluate the safety, tolerability, pharmacokinetics, and neutralization of VRC07-523LS, PGT121.414.LS, and PGDM14...

Birmingham, ALPHASE2200 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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NCT06263426Recruiting

Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)

This research is being done to better understand rejection in transplant recipients with HIV who receive kidneys from donors with vs without HIV....

Birmingham, ALNA200 participantsJohns Hopkins University

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NCT07292584Recruiting

Evaluating an Interactive Digital Toolkit for Women's PrEP Implementation

The goal of this study is to test if a Digital PrEP Toolkit helps cisgender women learn about and access PrEP in Alabama and Mississippi. PrEP is a medication that prevents HIV infection. The main que...

Birmingham, ALNA125 participantsUniversity of Alabama at Birmingham

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NCT06013579Recruiting

Effect of High-Intensity Exercise to Attenuate Cognitive Function Limitations and Train Exercise Habits in Older People Living With HIV

People aging with HIV are at higher risk for Alzheimer's disease and related dementias, and although physical activity is a promising target to mitigate such risk, this population engages in low level...

Birmingham, ALNA110 participantsUniversity of Alabama at Birmingham

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NCT06856174Recruiting

Menopausal HT for Women Living With HIV (HoT)

Women living with HIV have been shown to experience more frequent and severe hot flashes and night sweats (collectively known as vasomotor symptoms) as compared to women living without HIV. This corre...

Birmingham, ALPHASE4105 participantsAdvancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

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NCT07390955Recruiting

A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1

This study is testing a lab-made antibody called ePGT121v1-LS that targets a specific part of HIV. Researchers will give it by vein (IV) and under the skin (SC), both on its own and together with two ...

Birmingham, ALPHASE183 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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NCT07221123Recruiting

Boosting Olfactory and Sensory Training Study (BOOST)

The goal of this study is to examine two types of olfactory interventions (conventional olfactory training vs scented marker training) in adults with HIV. The two research questions are: 1. Determin...

Birmingham, ALPHASE280 participantsUniversity of Alabama at Birmingham

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NCT05384145Recruiting

Implementation Trial to Evaluate a Population Health Combination Intervention to Meet HIV Testing, Linkage, and Viral Suppression Goals in Alabama

The purpose of this study is to adapt and evaluate a combination intervention that includes: (1) a data-driven approach to directed community-based HIV testing to areas with high need, (2) Project Con...

Birmingham, ALNA80 participantsUniversity of Alabama at Birmingham

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NCT05965518Recruiting

High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Adults With HIV

This is a single site, randomized exercise trial with individuals at least 50 years of age living with HIV who experience suboptimal cognition. The overall goals of this proposal are to determine whet...

Birmingham, ALNA60 participantsUniversity of Alabama at Birmingham

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NCT07231640Recruiting

PrOTECT AL: PrEP Optimization Through Enhanced Continuum Tracking

The purpose of this study is to enhance and evaluate the implementation of a PrEP Care Continuum data dashboard across seven distinct clinical sites in Alabama. By leveraging real-time data and foster...

Birmingham, ALNA56 participantsUniversity of Alabama at Birmingham

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NCT05719441Recruiting

A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission

A5388 is a phase II, two-arm, randomized, double-blind, placebo-controlled study that will enroll 48 antiretroviral therapy (ART)-naïve adults with acute HIV infection (AHI) in order to determine whet...

Birmingham, ALPHASE248 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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About HIV AIDS Clinical Trials in Birmingham

HIV (human immunodeficiency virus) attacks the immune system and, if untreated, can lead to AIDS (acquired immunodeficiency syndrome). Antiretroviral therapy (ART) can control the virus and prevent transmission. Research continues to pursue a functional cure, long-acting therapies, and preventive vaccines.

There are currently 16 hiv aids clinical trials recruiting participants in Birmingham, AL. These studies are seeking a combined 10,019 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Gilead Sciences, University of Chicago and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

HIV AIDS Clinical Trials in Birmingham — FAQ

Are there hiv aids clinical trials in Birmingham?

Yes, there are 16 hiv aids clinical trials currently recruiting in Birmingham, AL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Birmingham?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Birmingham research site will contact you about next steps.

Are clinical trials in Birmingham free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Birmingham studies also compensate for your time and travel.

What hiv aids treatments are being tested?

The 16 active trials in Birmingham are testing new therapies including novel drugs, biologics, and treatment approaches for hiv aids.

Data updated July 21, 2026 from ClinicalTrials.gov