18 Obesity Clinical Trials in Birmingham, AL (2026)

Q: How do I join a clinical trial in Birmingham?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Birmingham research site will contact you.

Recruiting Obesity Studies in Birmingham

NCT07567001Recruiting

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

This study is being done to look at the safety and effect of NNC0487-0111 in people with Heart Failure with preserved Ejection Fraction (HFpEF) or Heart Failure with mildly reduced Ejection Fraction (...

Birmingham, ALPHASE35,610 participantsNovo Nordisk A/S

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NCT07667803Recruiting

A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM

This master study protocol, Study D7260C00015, covers 2 independent, pivotal studies, Study 1 and Study 2. Each study is a global, randomized, double-blind, parallel-group, multicenter, Phase III stud...

Birmingham, ALPHASE34,500 participantsAstraZeneca

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NCT07654361Recruiting

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

Study GSBR-1290-12 is a Phase 3 pivotal, multicenter, global, randomized, placebo-controlled, double-blind study to investigate the long-term efficacy, safety, and tolerability of 3 maintenance doses ...

Birmingham, ALPHASE33,600 participantsGasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics

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NCT07743463Recruiting

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

Study ASC30-301 (AURORA-1) is a Phase III, global, multicenter, randomized, double-blind, placebo-controlled study to investigate the long-term efficacy, safety, and tolerability of three maintenance ...

Birmingham, ALPHASE33,003 participantsAscletis Pharma (China) Co., Limited

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NCT07564414Recruiting

A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight

This clinical study is testing how the study medicine CagriSema helps people living with obesity, with or without type 2 diabetes (T2D), lose weight. The purpose of the study is to find out how safe a...

Birmingham, ALPHASE32,500 participantsNovo Nordisk A/S

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NCT07284875Recruiting

Efficacy and Safety of KAI-9531 in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes

The primary objective of the study is to determine the effects of KAI-9531 subcutaneous (SC) injection once weekly compared to placebo on percent change in body weight....

Birmingham, ALPHASE32,340 participantsKailera

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NCT07351045Recruiting

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

The purpose of this study is to assess the efficacy and safety of enicepatide, a dual glucagon like peptide-1 (GLP-1)/glucose-dependent insulinotropic polypeptide (GIP) receptor agonist (RA), at multi...

Birmingham, ALPHASE32,000 participantsHoffmann-La Roche

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NCT07743450Recruiting

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

Study ASC30-302 (AURORA-2) is a Phase III, global, multicenter, randomized, double-blind, placebo-controlled study to investigate the long-term efficacy, safety, and tolerability of three maintenance ...

Birmingham, ALPHASE31,560 participantsAscletis Pharma (China) Co., Limited

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NCT07654374Recruiting

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

This is randomized, double-blind, placebo-controlled study of the long-term efficacy, safety, and tolerability of multiple doses of aleniglipron in participants living with overweight or obesity and T...

Birmingham, ALPHASE31,100 participantsGasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics

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NCT07282600Recruiting

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

The main purpose of this study is to evaluate the efficacy and safety of eloralintide compared with placebo for body weight reduction in participants with overweight or obesity and type 2 diabetes. Pa...

Birmingham, ALPHASE31,035 participantsEli Lilly and Company

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NCT07392190Recruiting

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

The main purpose of this study is to evaluate the efficacy and safety of eloralintide compared with placebo in participants with persistent obesity or overweight, with or without type 2 diabetes, and ...

Birmingham, ALPHASE3900 participantsEli Lilly and Company

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NCT06785064Recruiting

Optimizing an Extended Care Intervention to Promote Weight Loss Maintenance

The purpose of this study is to find out what combination of components, if any, offers the best support for keeping weight off after someone loses weight. Long term weight loss maintenance is a chall...

Birmingham, ALNA544 participantsUniversity of Alabama at Birmingham

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NCT07770841Recruiting

Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight

The purpose of this study is to see how oral semaglutide, when taken in lower doses help lowering of body weight in participants with excess body weight when compared to 'dummy' tablets (placebo). Res...

Birmingham, ALPHASE3450 participantsNovo Nordisk A/S

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NCT07662122Recruiting

A Study to Test Whether BI 3034701 Helps People to Lose Weight Who Live With Obesity or Overweight

This study is open to adults between 18 and 74 years of age and who have a body mass index (BMI) of 30 kg/m2 or more, or a BMI of 27 kg/m2 or more and at least 1 health problem related to their weight...

Birmingham, ALPHASE2300 participantsBoehringer Ingelheim

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NCT04971720Recruiting

PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis

Obese individuals have a higher prevalence of nocturnal hypertension and non-dipping blood pressure (BP). These conditions are associated with an increased risk of cardiovascular (CV) events and death...

Birmingham, ALPHASE2160 participantsUniversity of Alabama at Birmingham

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NCT06239116Recruiting

A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment

The purpose of this study is to evaluate the safety, tolerability, and PK of RM-718 in healthy subjects with obesity and in patients with MC4R Pathway Impairment...

Birmingham, ALPHASE1150 participantsRhythm Pharmaceuticals, Inc.

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NCT06760546Recruiting

A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)

This is a sub-study of Study RM-493-040 (NCT05774756). The goal of this sub-study is to learn how well Setmelanotide works to improve weight reduction, hunger, and quality of life in patients 4 years...

Birmingham, ALPHASE339 participantsRhythm Pharmaceuticals, Inc.

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NCT06736028Recruiting

Ketogenic Diets for Weight Loss Maintenance: Impact on Energy Expenditure and Appetite in Individuals With Obesity

The goal of this clinical trial is to investigate whether a Ketogenic Diet (KD) can increase Total Energy Expenditure (TEE), while benefiting appetite, during weight loss maintenance in reduced-obese ...

Birmingham, ALNA20 participantsUniversity of Alabama at Birmingham

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About Obesity Clinical Trials in Birmingham

Obesity is a complex chronic disease involving an excessive amount of body fat that increases the risk of other diseases and health problems. It affects over 650 million adults worldwide. Treatment approaches include lifestyle modifications, medications (GLP-1 agonists), and bariatric surgery.

There are currently 18 obesity clinical trials recruiting participants in Birmingham, AL. These studies are seeking a combined 29,811 participants. Research is being sponsored by Novo Nordisk A/S, AstraZeneca, Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics and 7 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Obesity Clinical Trials in Birmingham — FAQ

Are there obesity clinical trials in Birmingham?

Yes, there are 18 obesity clinical trials currently recruiting in Birmingham, AL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Birmingham?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Birmingham research site will contact you about next steps.

Are clinical trials in Birmingham free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Birmingham studies also compensate for your time and travel.

What obesity treatments are being tested?

The 18 active trials in Birmingham are testing new therapies including novel drugs, biologics, and treatment approaches for obesity.

Data updated August 31, 2026 from ClinicalTrials.gov