Birmingham, MICHIGAN9 Active Studies

Heart Failure Clinical Trials in Birmingham, MICHIGAN

Find 9 actively recruiting heart failure clinical trials in Birmingham, MICHIGAN. Connect with local research sites and explore new treatment options.

9
Active Trials
8
Sponsors
20,920
Enrolling

Recruiting Heart Failure Studies in Birmingham

RecruitingBirmingham, MICHIGANNCT06677060

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

Participants include men and women ≥ 40 years of age with T2DM, established CV disease, a history of HTN with an SBP of at least 130 mmHg at screening, who meet the predefined serum potassium level, a...

11,300 participants
AstraZeneca
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RecruitingBirmingham, MICHIGANNCT06307652

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

This is a Phase III, international, multi-centre, randomised, double-blind, parallel-group, double-dummy, active-controlled, event-driven study in patients with chronic HF and impaired kidney function...

4,800 participants
AstraZeneca
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RecruitingBirmingham, MICHIGANNCT02901184

Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction

Heart failure with preserved ejection fraction (HFPEF) is common and deadly but without therapy. Inconclusive studies such as TOPCAT (Treatment of Preserved Cardiac Function Heart Failure With an Aldo...

2,000 participants
Uppsala University
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RecruitingBirmingham, MICHIGANNCT06736574

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

The purpose of this study is to find out if the investigational drug called omecamtiv mecarbil can reduce the risk of the effects of heart failure, like hospitalization, transplantation, or death in p...

1,800 participants
Cytokinetics
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RecruitingBirmingham, MICHIGANNCT06369298

Study of JK07 in Patients With Chronic Heart Failure

This is a Phase 2, randomized, double-blind, placebo-controlled, multiple dose study to assess the safety, tolerability, and efficacy of JK07 in participants aged 18-85 with heart failure. There will...

282 participants
Salubris Biotherapeutics Inc
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RecruitingBirmingham, MICHIGANNCT06122779

Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

The purpose of this study is to evaluate the safety, tolerability, and exposure-response (E-R) of BMS-986435/MYK-224 in participants with symptomatic Heart Failure with Preserved Ejection Fraction (HF...

208 participants
Bristol-Myers Squibb
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RecruitingBirmingham, MICHIGANNCT06979362

A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy

This study will look into how CDR132L (a potential new medicine) works on the structure and function of the heart in people living with heart failure. Participants will either get CDR132L or placebo (...

200 participants
Novo Nordisk A/S
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RecruitingBirmingham, MICHIGANNCT06616974

A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)

TX000045-003 is a double-blind, randomized, parallel group, placebo-controlled, proof- of-concept (POC) study, evaluating 2 dose regimens of TX000045 over the course of a 24-week treatment period (the...

180 participants
Tectonic Therapeutic
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RecruitingBirmingham, MICHIGANNCT05598333

Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects With Non-Ischemic NYHA Class III Heart Failure

This is a Phase 2 adaptive, double-blinded, placebo-controlled, randomized, multi-center trial study to evaluate the safety and efficacy of a single dose of AB-1002, administered via antegrade intraco...

150 participants
AskBio Inc
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About Heart Failure Clinical Trials in Birmingham

Heart failure is a chronic condition where the heart cannot pump blood efficiently to meet the body's needs. It affects millions of people worldwide and can result from various heart conditions. Treatment includes medications, lifestyle changes, devices, and in severe cases, heart transplant.

There are currently 9 heart failure clinical trials recruiting participants in Birmingham, MICHIGAN. These studies are seeking a combined 20,920 participants. Research is being sponsored by AstraZeneca, Uppsala University, Cytokinetics and 5 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Heart Failure Clinical Trials in Birmingham — FAQ

Are there heart failure clinical trials in Birmingham?

Yes, there are 9 heart failure clinical trials currently recruiting in Birmingham, MICHIGAN. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Birmingham?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Birmingham research site will contact you about next steps.

Are clinical trials in Birmingham free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Birmingham studies also compensate for your time and travel.

What heart failure treatments are being tested?

The 9 active trials in Birmingham are testing new therapies including novel drugs, biologics, and treatment approaches for heart failure.

Data updated March 2, 2026 from ClinicalTrials.gov