5 Diffuse Large B-Cell Lymphoma Clinical Trials in Boston, MA (2026)

Q: How do I join a clinical trial in Boston?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you.

Recruiting Diffuse Large B-Cell Lymphoma Studies in Boston

NCT06091865Recruiting

A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma

This study is researching an experimental drug called odronextamab, referred to as study drug, when used in combination with chemotherapy. The study is focused on patients with Diffuse Large B-cell Ly...

Boston, MAPHASE3904 participantsRegeneron Pharmaceuticals

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NCT07654426Recruiting

The CARDIOPROTECT Trial

This trial is to evaluate if dexrazoxane is safer and more effective than liposomal doxorubicin in preventing heart failure events in participants with diffuse large B-cell lymphoma (DLBCL) undergoing...

Boston, MAPHASE260 participantsBeth Israel Deaconess Medical Center

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NCT05905328Recruiting

Study of CTO1681 for the Prevention and Treatment of CRS in DLBCL Patients Receiving CAR T-Cell Therapy

This is an interventional study to evaluate the use of CTO1681 in preventing or reducing CAR T-cell-induced toxicities like cytokine release syndrome (CRS). This study will enroll adult patients with ...

Boston, MAPHASE154 participantsCytoAgents, Inc.

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NCT06811272Recruiting

Outpatient Epcoritamab as 2L in NTE R/R DLBCL

The purpose of this study is to measure the efficacy of the study drug, epcoritamab, in participants with relapsed/refractory large B-cell lymphoma....

Boston, MAPHASE240 participantsMassachusetts General Hospital

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NCT06550141Recruiting

Emapalumab Prevention of CAR-T Cell Associated Toxicities

This research study involves assessing the impact of emapalumab as preventative management of CAR-T related cytokine release syndrome in participants with Non-Hodgkin's lymphoma (NHL). The research s...

Boston, MAPHASE228 participantsMarcela V. Maus, M.D.,Ph.D.

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About Diffuse Large B-Cell Lymphoma Clinical Trials in Boston

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma, accounting for about 30% of cases. It is an aggressive lymphoma that grows rapidly. Treatment usually involves chemoimmunotherapy, with CAR-T cell therapy for relapsed cases.

There are currently 5 diffuse large b-cell lymphoma clinical trials recruiting participants in Boston, MA. These studies are seeking a combined 1,086 participants. Research is being sponsored by Regeneron Pharmaceuticals, Beth Israel Deaconess Medical Center, CytoAgents, Inc. and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Diffuse Large B-Cell Lymphoma Clinical Trials in Boston — FAQ

Are there diffuse large b-cell lymphoma clinical trials in Boston?

Yes, there are 5 diffuse large b-cell lymphoma clinical trials currently recruiting in Boston, MA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What diffuse large b-cell lymphoma treatments are being tested?

The 5 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for diffuse large b-cell lymphoma.

Data updated October 16, 2026 from ClinicalTrials.gov