9 Endometrial Cancer Clinical Trials in Boston, MA (2026)

Q: How do I join a clinical trial in Boston?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you.

Recruiting Endometrial Cancer Studies in Boston

NCT06293898Recruiting

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

The objective of this study is to evaluate the safety, tolerability, and efficacy of BL-M07D1 in patients with HER2 expressing advanced tumors....

Boston, MAPHASE1280 participantsSystImmune Inc.

View Study Details

NCT04486352Recruiting

A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer

This is a Phase IB/II multi-cohort study designed to evaluate the efficacy and safety of targeted agents with or without cancer immune checkpoint therapy with atezolizumab in participant with recurren...

Boston, MAPHASE1148 participantsAlliance Foundation Trials, LLC.

View Study Details

NCT03675893Recruiting

RESOLVE: Abemaciclib + Letrozole +/- Metformin, Zotatifin, or Gedatolisib in Endometrial or Low-Grade Serous Ovarian Cancer

This research study is studying a combination of targeted therapies as a possible treatment for estrogen-receptor positive (ER+) endometrial cancer and low-grade serous ovarian cancer. The drugs invo...

Boston, MAPHASE2110 participantsDana-Farber Cancer Institute

View Study Details

NCT02491099Recruiting

A Phase II Evaluation of Afatinib in Patients With Persistent or Recurrent HER2-positive Uterine Serous Carcinoma

Primary Objective: To assess the activity of Afatinib in patients with persistent or recurrent uterine serous carcinoma overexpressing HER2/neu with the frequency of patients who survive progression-f...

Boston, MAPHASE250 participantsYale University

View Study Details

NCT06366347Recruiting

ALPINE: Maintenance Letrozole/Abemaciclib vs Pembrolizumab

A standard treatment for endometrial cancer is chemotherapy and pembrolizumab together followed by pembrolizumab maintenance for two years. This treatment regimen has shown benefit in terms of delayin...

Boston, MAPHASE232 participantsDana-Farber Cancer Institute

View Study Details

NCT04839614Recruiting

Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia

To assess the feasibility of an expedited referral process for the obese endometrial cancer or EIN patient from her gynecologic oncologist to the Brigham Center for Metabolic and Bariatric Surgery (CM...

Boston, MANA30 participantsDana-Farber Cancer Institute

View Study Details

NCT06369155Recruiting

Azenosertib in Uterine Serous Carcinoma: Biomarker Study

This research study is being done to investigate how Azenosertib affects tumor cells of persistent or recurrent uterine serous carcinoma. The name of the study drug involved in this study is: -Azeno...

Boston, MAPHASE225 participantsJoyce Liu, MD

View Study Details

NCT06518564Recruiting

Avelumab and M1774 in ARID1A-mutated Endometrial Cancer

The purpose of this research study is to see if the combination of study drugs avelumab and M1774 is effective and safe for participants with endometrial cancer. The names of the study drugs involved...

Boston, MAPHASE225 participantsPanagiotis Konstantinopoulos, MD, PhD

View Study Details

NCT07220239Recruiting

Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome

Study Goal: This pilot study wants to find out if using a menstrual cup can be a good, non-invasive way to collect samples from the lining of the uterus (called the endometrium) to help screen for en...

Boston, MANA25 participantsJessica D. St. Laurent, MD

View Study Details

About Endometrial Cancer Clinical Trials in Boston

Endometrial cancer begins in the lining of the uterus and is the most common gynecologic cancer. It is often detected early due to abnormal bleeding symptoms. Treatment typically involves surgery, with radiation, chemotherapy, or hormone therapy for advanced cases.

There are currently 9 endometrial cancer clinical trials recruiting participants in Boston, MA. These studies are seeking a combined 725 participants. Research is being sponsored by SystImmune Inc., Alliance Foundation Trials, LLC., Dana-Farber Cancer Institute and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Endometrial Cancer Clinical Trials in Boston — FAQ

Are there endometrial cancer clinical trials in Boston?

Yes, there are 9 endometrial cancer clinical trials currently recruiting in Boston, MA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What endometrial cancer treatments are being tested?

The 9 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for endometrial cancer.

Data updated October 12, 2026 from ClinicalTrials.gov