31 Fibromyalgia Clinical Trials in Boston, MA (2026)

Q: How do I join a clinical trial in Boston?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you.

Recruiting Fibromyalgia Studies in Boston

NCT03059420Recruiting

Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies

The purpose of this study is to identify genes associated with impaired development and function of the cranial nerves and brainstem, which may result in misalignment of the eyes (strabismus) and rela...

Boston, MA20,000 participantsBoston Children's Hospital

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NCT06515860Recruiting

Neurofibromatosis Type 1 Tumor Early Detection Study

The goal of this observational study is to determine if a liquid biopsy (i.e. blood test) is an effective clinical tool for monitoring the development of malignant peripheral nerve sheath tumor (MPNST...

Boston, MA1,000 participantsDavid Miller

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NCT07048574Recruiting

TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age

This is a longitudinal, observational epidemiological study designed to estimate the prevalence of depression, anxiety, and behavior problems in children ages 18 months through 11 years with cystic fi...

Boston, MA600 participantsState University of New York at Buffalo

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NCT06262113Recruiting

A Decentralized Clinical Trial to Promote Evidence-Based Care for Underserved Patients With Neurofibromatosis 1

The goal of this fully decentralized, randomized controlled trial is to compare the efficacy of two educational interventions for individuals with Neurofibromatosis 1 (NF1). The primary objective of t...

Boston, MA294 participantsMassachusetts General Hospital

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NCT04509050Recruiting

Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children

This is a two-part, multi-center, prospective longitudinal, exploratory study of highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators and their impact on children wit...

Boston, MA210 participantsSonya Heltshe

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NCT01401998Recruiting

ARPKD Database Study

Hepato-renal fibrocystic diseases (HRFD) is a term developed that encompasses rare diseases such as Autosomal Recessive Polycystic Kidney Disease (ARPKD), and other diseases with common features (Joub...

Boston, MA200 participantsChildren's Hospital of Philadelphia

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NCT06837181Recruiting

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

This multicenter cross-sectional study will include a diverse population of adolescents and adults with CF. The overall Aim is to describe prevalence of diabetes microvascular complications and macro...

Boston, MA200 participantsJaeb Center for Health Research

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NCT06188741Recruiting

Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1

Plexiform neurofibromas (PN) are known to cause significant morbidity in children with NF1. The recent FDA approval for selumetinib in children 2 years and older with inoperable symptomatic PN was bas...

Boston, MA200 participantsUniversity of Alabama at Birmingham

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NCT06237335Recruiting

A Phase 2 Study Evaluating Safety and Tolerability of RCT2100 (CFTR mRNA) in Healthy Participants and in Participants With CF

This is the first-in-human study with RCT2100 and is designed to provide safety and tolerability data for future clinical studies....

Boston, MA192 participantsReCode Therapeutics

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NCT06449677Recruiting

Bionic Pancreas in CFRD

This multi-center randomized controlled trial (RCT) will compare efficacy and safety endpoints using the insulin-only configuration of the iLet Bionic Pancreas System (BP) versus a control group using...

Boston, MA150 participantsJaeb Center for Health Research

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NCT06296394Recruiting

Health Outcomes of Parents With Cystic Fibrosis-Aim 2

The goal of this observational prospective study is to determine the health impact of parenthood on United States (US) people with CF in the era of CF transmembrane regulator protein (CFTR) modulators...

Boston, MA146 participantsUniversity of Pittsburgh

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NCT04374305Recruiting

Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)

This is a multi-arm phase II platform-basket screening study designed to test multiple experimental therapies simultaneously in patients with NF2-related schwannomatosis (NF2-SWN, formerly known as ne...

Boston, MA109 participantsScott R. Plotkin, MD, PhD

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NCT03535545Recruiting

Preliminary Evaluation of [68Ga]CBP8 in Healthy Individuals, Lung Cancer, and Idiopathic Pulmonary Fibrosis Patients

The goal of this study is to investigate the safety of \[68Ga\]CBP8 and its efficacy to detect collagen deposition in pulmonary fibrosis....

Boston, MA100 participantsMassachusetts General Hospital

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NCT07201922Recruiting

A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis

This study is open to people aged 40 years or older who have at least 1 family member with pulmonary fibrosis. Pulmonary fibrosis is a condition where lung tissue becomes scarred, making it harder to ...

Boston, MA80 participantsBoehringer Ingelheim

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NCT07071324Recruiting

CF Wellness Program

This study is a pilot randomized control trial (RCT; N=80) comparing the Cystic Fibrosis Wellness Program (CFWP) to usual care (UC) to evaluate (1) Intervention Adherence (completion of the CFWP Coach...

Boston, MA80 participantsJohns Hopkins University

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NCT06343805Recruiting

A Phase 1 Study of AJ1-11095 in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)

AJX-101 is a first-in-human (FIH), phase 1, non-randomized, multi-center, open-label clinical trial designed to investigate the safety, tolerability, pharmacokinetics (PK), clinical activity and chang...

Boston, MA76 participantsAjax Therapeutics, Inc.

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NCT06429176Recruiting

Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients with Cystic Fibrosis

The goal of this clinical trial is to learn if drug SPL84 is safe for adult patients with cystic fibrosis (CF). It will also learn if the drug works to treat works to treat CF with a specific mutation...

Boston, MA64 participantsSpliSense Ltd.

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NCT06009159Recruiting

Vagus Nerve Stimulation(VNS) As Treatment For Fibromyalgia Patients

Fibromyalgia (FM) is a syndrome with clinical symptoms involving multiple systems. The efficacy of current treatments is inadequate, and more alternative modalities are needed for the management of FM...

Boston, MA60 participantsMassachusetts General Hospital

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NCT06532071Recruiting

Advanced Imaging for Pulmonary Fibrosis

The purpose of this study is to determine if measurements of active collagen deposition using \[68Ga\]CBP8 positron emission tomography (PET) and tissue injury using dynamic contrast-enhanced magnetic...

Boston, MA60 participantsPeter Caravan

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NCT05028829Recruiting

Safety and Efficacy of Atorvastatin v. Placebo on HCC Risk

Prospective randomized, multi-center, double blind placebo-controlled trial to assess the chemopreventive impact of atorvastatin (20 mg oral) vs placebo in up to 60 adults with advanced fibrosis at hi...

Boston, MA60 participantsRaymond Chung

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NCT07031323Recruiting

OnTrackCF: Engagement, Feasibility, and Acceptability Study

This is a multi-site, nonrandomized study using mixed methods approach to evaluate the feasibility, acceptability, and user engagement of OnTrackCF for adults with Cystic Fibrosis (AWCF)....

Boston, MA60 participantsBoston Children's Hospital

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NCT07233408Recruiting

Tailoring an Online Platform to Promote Evidence-Based Care for Adults With Neurofibromatosis 1 and Low Health Literacy

This decentralized, randomized study seeks to assess the feasibility, acceptability, and preliminary effectiveness of two approaches to assisting Neurofibromatosis 1 (NF1) patients with low health lit...

Boston, MA50 participantsMassachusetts General Hospital

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NCT06773195Recruiting

A Study of Ruxolitinib in Combination With Ulixertinib in People With Myelofibrosis

The researchers are doing this study to find out whether the combination of ruxolitinib and ulixertinib is a safe and effective treatment for people with myelofibrosis. The researchers will test diffe...

Boston, MA37 participantsMemorial Sloan Kettering Cancer Center

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NCT07023523Recruiting

Self-regulation of Real-time fMRI Brain Activity in Chronic Pain

This study aims to explore the usefulness of self-regulation of brain activity in patients with fibromyalgia. Patients will use real-time functional magnetic resonance imaging (fMRI) neurofeedback to ...

Boston, MA36 participantsBrigham and Women's Hospital

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NCT06216704Recruiting

Skeletal Health and Bone Marrow Composition in Adolescents With Cystic Fibrosis

The investigators will be evaluating bone marrow composition via magnetic resonance imaging in adolescents diagnosed with cystic fibrosis (CF) compared to healthy, matched controls. The investigators ...

Boston, MA36 participantsMassachusetts General Hospital

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NCT06747858Recruiting

Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

ARCT-032-02 is a Phase 2, open-label, multicenter, multiple-ascending dose study of ARCT-032 in adults with CF who are not eligible for CFTR modulator therapy or are not taking CFTR modulators due to ...

Boston, MA33 participantsArcturus Therapeutics, Inc.

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NCT05248230Recruiting

4D-710 in Adult Patients With Cystic Fibrosis

This is a Phase 1/2 multicenter, open-label, single dose trial of 4D-710 investigational gene therapy in adults with cystic fibrosis....

Boston, MA30 participants4D Molecular Therapeutics

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NCT07104799Recruiting

Momelotinib During and After HCT in Myelofibrosis

This is a single-center, open-label, phase I study to determine the safety and tolerability of momelotinib in patients with myelofibrosis during and after hematopoietic cell transplantation (HCT)....

Boston, MA28 participantsMassachusetts General Hospital

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NCT06810167Recruiting

Assessing Tenapanor as a Treatment of CF-related Constipation.

Tenapanor is the newest FDA-approved drug for IBS with constipation (IBS-C). This study seeks to understand tenapanor as a treatment for cystic fibrosis-related constipation (CFrC) in CF patients. Par...

Boston, MA25 participantsMassachusetts General Hospital

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NCT05723445Recruiting

The Effects of a Low Glycemic Load Diet on Dysglycemia and Body Composition in Adults With Cystic Fibrosis-Related Diabetes

This study will evalute the effect of a low glycemic load (LGL diet on dysglycemia, insulin requirements, DXA-derived body composition, gastrointestinal symptoms and quality of life measures in adults...

Boston, MA15 participantsRhode Island Hospital

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NCT06526923Recruiting

A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF)

This is a Phase 1/2 multicenter, open-label, single dose trial of SP-101 investigational gene therapy in adults with CF who are ineligible for or intolerant to CFTR modulator therapy....

Boston, MA15 participantsSpirovant Sciences, Inc.

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About Fibromyalgia Clinical Trials in Boston

Fibromyalgia is a condition characterized by widespread musculoskeletal pain, fatigue, sleep disturbance, and cognitive difficulties. It affects about 2-4% of the population, predominantly women. Treatment includes medications, exercise, stress management, and cognitive behavioral therapy.

There are currently 31 fibromyalgia clinical trials recruiting participants in Boston, MA. These studies are seeking a combined 24,246 participants. Research is being sponsored by Boston Children's Hospital, David Miller, State University of New York at Buffalo and 20 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Fibromyalgia Clinical Trials in Boston — FAQ

Are there fibromyalgia clinical trials in Boston?

Yes, there are 31 fibromyalgia clinical trials currently recruiting in Boston, MA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What fibromyalgia treatments are being tested?

The 31 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for fibromyalgia.

Data updated July 13, 2026 from ClinicalTrials.gov