3 Myelofibrosis Clinical Trials in Boston, MA (2026)

Q: How do I join a clinical trial in Boston?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you.

Recruiting Myelofibrosis Studies in Boston

NCT06343805Recruiting

A Phase 1 Study of AJ1-11095 in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)

AJX-101 is a first-in-human (FIH), phase 1, non-randomized, multi-center, open-label clinical trial designed to investigate the safety, tolerability, pharmacokinetics (PK), clinical activity and chang...

Boston, MAPHASE1256 participantsAjax Therapeutics, Inc.

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NCT06773195Recruiting

A Study of Ruxolitinib in Combination With Ulixertinib in People With Myelofibrosis

The researchers are doing this study to find out whether the combination of ruxolitinib and ulixertinib is a safe and effective treatment for people with myelofibrosis. The researchers will test diffe...

Boston, MAPHASE137 participantsMemorial Sloan Kettering Cancer Center

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NCT07104799Recruiting

Momelotinib During and After HCT in Myelofibrosis

This is a single-center, open-label, phase I study to determine the safety and tolerability of momelotinib in patients with myelofibrosis during and after hematopoietic cell transplantation (HCT)....

Boston, MAPHASE128 participantsMassachusetts General Hospital

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About Myelofibrosis Clinical Trials in Boston

Myelofibrosis is a serious bone marrow disorder that disrupts normal blood cell production, leading to extensive scarring in the bone marrow. It can cause severe anemia, weakness, and an enlarged spleen. Treatment includes JAK inhibitors, blood transfusions, and stem cell transplant.

There are currently 3 myelofibrosis clinical trials recruiting participants in Boston, MA. These studies are seeking a combined 321 participants. Research is being sponsored by Ajax Therapeutics, Inc., Memorial Sloan Kettering Cancer Center, Massachusetts General Hospital. Clinical trial participation is free and participants receive study-related medical care at no cost.

Myelofibrosis Clinical Trials in Boston — FAQ

Are there myelofibrosis clinical trials in Boston?

Yes, there are 3 myelofibrosis clinical trials currently recruiting in Boston, MA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What myelofibrosis treatments are being tested?

The 3 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for myelofibrosis.

Data updated October 15, 2026 from ClinicalTrials.gov