Boston, MA4 Active Studies

Myeloproliferative Neoplasms Clinical Trials in Boston, MA

Find 4 actively recruiting myeloproliferative neoplasms clinical trials in Boston, MA. Connect with local research sites and explore new treatment options.

4
Active Trials
4
Sponsors
782
Enrolling

Recruiting Myeloproliferative Neoplasms Studies in Boston

RecruitingBoston, MANCT03662126

KRT-232 Versus Best Available Therapy for the Treatment of Subjects With Myelofibrosis Who Are Relapsed or Refractory to JAK Inhibitor Treatment

This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, for the treatment of patients with myelofibrosis (MF) who no longer benefit from treatment with a JAK inhibitor. Inhibition...

385 participants
Kartos Therapeutics, Inc.
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RecruitingBoston, MANCT06079879

A Study of Bomedemstat (IMG-7289/MK-3543) Compared to Best Available Therapy (BAT) in Participants With Essential Thrombocythemia and an Inadequate Response or Intolerance of Hydroxyurea (MK-3543-006)

This is a study evaluating the safety and efficacy of bomedemstat (MK-3543) compared with the best available therapy (BAT) in participants with essential thrombocythemia (ET) who have an inadequate re...

300 participants
Merck Sharp & Dohme LLC
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RecruitingBoston, MANCT04644211

Ruxolitinib in Thrombocythemia and Polycythemia Vera

This research is being done to see if the drug ruxolitinib is effective in reducing the symptoms caused by low-risk essential thrombocythemia (ET) and polycythemia vera (PV). \- This research study i...

60 participants
Massachusetts General Hospital
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RecruitingBoston, MANCT06773195

A Study of Ruxolitinib in Combination With Ulixertinib in People With Myelofibrosis

The researchers are doing this study to find out whether the combination of ruxolitinib and ulixertinib is a safe and effective treatment for people with myelofibrosis. The researchers will test diffe...

37 participants
Memorial Sloan Kettering Cancer Center
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About Myeloproliferative Neoplasms Clinical Trials in Boston

Myeloproliferative neoplasms (MPNs) are blood cancers in which the bone marrow overproduces red blood cells, platelets, or white blood cells. Types include polycythemia vera, essential thrombocythemia, and myelofibrosis. Treatment depends on the specific type and risk factors.

There are currently 4 myeloproliferative neoplasms clinical trials recruiting participants in Boston, MA. These studies are seeking a combined 782 participants. Research is being sponsored by Kartos Therapeutics, Inc., Merck Sharp & Dohme LLC, Massachusetts General Hospital and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Myeloproliferative Neoplasms Clinical Trials in Boston — FAQ

Are there myeloproliferative neoplasms clinical trials in Boston?

Yes, there are 4 myeloproliferative neoplasms clinical trials currently recruiting in Boston, MA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What myeloproliferative neoplasms treatments are being tested?

The 4 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for myeloproliferative neoplasms.

Data updated March 2, 2026 from ClinicalTrials.gov