6 Myeloproliferative Neoplasms Clinical Trials in Boston, MA (2026)

Q: How do I join a clinical trial in Boston?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you.

Recruiting Myeloproliferative Neoplasms Studies in Boston

NCT06034002Recruiting

A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms

This study is being conducted to evaluate the safety, tolerability, dose-limiting toxicity (DLT) and determine the maximum tolerated dose (MTD) and/or recommended dose(s) for expansion (RDE) of INCA03...

Boston, MAPHASE1290 participantsIncyte Corporation

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NCT06343805Recruiting

A Phase 1 Study of AJ1-11095 in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)

AJX-101 is a first-in-human (FIH), phase 1, non-randomized, multi-center, open-label clinical trial designed to investigate the safety, tolerability, pharmacokinetics (PK), clinical activity and chang...

Boston, MAPHASE1256 participantsAjax Therapeutics, Inc.

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NCT07441694Recruiting

Study of INCA036978 in Participants With Myeloproliferative Neoplasms

This study will be conducted to determine the safety, tolerability, dose-limiting toxicity (DLT)s, and maximum tolerated dose (MTD) and/or recommended dose for expansion (RDE)s of INCA036978 administe...

Boston, MAPHASE1218 participantsIncyte Corporation

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NCT04644211Recruiting

Ruxolitinib in Thrombocythemia and Polycythemia Vera

This research is being done to see if the drug ruxolitinib is effective in reducing the symptoms caused by low-risk essential thrombocythemia (ET) and polycythemia vera (PV). \- This research study i...

Boston, MAPHASE260 participantsMassachusetts General Hospital

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NCT06773195Recruiting

A Study of Ruxolitinib in Combination With Ulixertinib in People With Myelofibrosis

The researchers are doing this study to find out whether the combination of ruxolitinib and ulixertinib is a safe and effective treatment for people with myelofibrosis. The researchers will test diffe...

Boston, MAPHASE137 participantsMemorial Sloan Kettering Cancer Center

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NCT07104799Recruiting

Momelotinib During and After HCT in Myelofibrosis

This is a single-center, open-label, phase I study to determine the safety and tolerability of momelotinib in patients with myelofibrosis during and after hematopoietic cell transplantation (HCT)....

Boston, MAPHASE128 participantsMassachusetts General Hospital

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About Myeloproliferative Neoplasms Clinical Trials in Boston

Myeloproliferative neoplasms (MPNs) are blood cancers in which the bone marrow overproduces red blood cells, platelets, or white blood cells. Types include polycythemia vera, essential thrombocythemia, and myelofibrosis. Treatment depends on the specific type and risk factors.

There are currently 6 myeloproliferative neoplasms clinical trials recruiting participants in Boston, MA. These studies are seeking a combined 889 participants. Research is being sponsored by Incyte Corporation, Ajax Therapeutics, Inc., Massachusetts General Hospital and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Myeloproliferative Neoplasms Clinical Trials in Boston — FAQ

Are there myeloproliferative neoplasms clinical trials in Boston?

Yes, there are 6 myeloproliferative neoplasms clinical trials currently recruiting in Boston, MA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What myeloproliferative neoplasms treatments are being tested?

The 6 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for myeloproliferative neoplasms.

Data updated October 12, 2026 from ClinicalTrials.gov