20 Parkinsons Disease Clinical Trials in Boston, MA (2026)

Q: How do I join a clinical trial in Boston?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you.

Recruiting Parkinsons Disease Studies in Boston

NCT06376994Recruiting

Multi-Center Clean Air Randomized Controlled Trial in COPD

This is a multi-center randomized, sham-controlled clinical trial to determine the effectiveness of an air cleaner intervention aimed at improving indoor air quality on reducing COPD exacerbation risk...

Boston, MAPHASE3770 participantsJHSPH Center for Clinical Trials

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NCT05204888Recruiting

myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home

Parallel-group, prospective, randomized, controlled phase III trial of home High flow Nasal Therapy (HFNT) via myAirvo 3 plus usual COPD medical care vs. usual COPD medical care, for at least 1 year a...

Boston, MANA642 participantsTemple University

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NCT06891755Recruiting

Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

The objective of this study is to assess the safety and efficacy of Apreo BREATHE system when used to support native airways and release trapped air in the treatment of adult COPD patients with emphys...

Boston, MANA250 participantsApreo Health, Inc.

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NCT07567794Recruiting

GBPDC: Gut-Brain in PD Consortium Master Protocol

The purpose of this research study is to identify the role that the gut-brain axis, the group of nerves that connect the brain and gut, plays in Parkinson's disease (PD). The National Institute of Dia...

Boston, MA250 participantsDuke University

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NCT07705373Recruiting

A Novel Digital Music-based Autonomous Personalized Walking Intervention to Improve Gait and Walking Automaticity in Parkinson Disease

The purpose of this research study is to examine the effects of a 3-month personalized community-based walking program called MyMusiQ. The study uses music cues delivered through a digital device in p...

Boston, MANA200 participantsBoston University Charles River Campus

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NCT07644559Recruiting

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

This study will assess the safety and efficacy of VS-7375 alone and in combination with cetuximab in patients with metastatic KRAS G12D - mutated Pancreatic Cancer...

Boston, MAPHASE2185 participantsVerastem, Inc.

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NCT06855433Recruiting

Colchicine to Reduce Your SympToms And Lower Levels of Inflammation, Zeroing in on Effective CPPD Disease Treatment

The goal of this clinical trial is to learn if colchicine reduces levels of proteins indicating inflammation in the blood in individuals with calcium pyrophosphate deposition (CPPD) disease. The trial...

Boston, MAPHASE2150 participantsBrigham and Women's Hospital

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NCT05701982Recruiting

The Effect of a Technology-Mediated Integrated Walking and Tai Chi Intervention on Physical Function in Veterans With COPD and Chronic Musculoskeletal Pain

Persons with COPD benefit from being physically active, but they are often limited by chronic musculoskeletal pain. This project will determine whether a non-pharmacologic, integrated, technology-medi...

Boston, MANA136 participantsVA Office of Research and Development

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NCT05937854Recruiting

Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH

The investigators will study whether the drug tadalafil improves shortness of breath in 126 Veterans with Chronic Obstructive Pulmonary Disease (COPD) and high blood pressure in the lungs. The investi...

Boston, MAPHASE2126 participantsVA Office of Research and Development

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NCT04286308Recruiting

Cortical-Basal Ganglia Speech Networks

In this research study the researchers want to learn more about brain activity related to speech perception and production....

Boston, MANA80 participantsMassachusetts General Hospital

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NCT07455760Recruiting

Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator Recipients

This study will examine how two important brain circuits - one involving the subthalamic nucleus (STN) and one involving the ventral intermediate nucleus of the thalamus (VIM) - contribute to learning...

Boston, MANA80 participantsBoston University Charles River Campus

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NCT06425731Recruiting

Dance and Energy Expenditure Among Adults With Parkinson's

The first purpose of the study is to develop and test new methods for quantifying dance among adults with a diagnosis of Parkinson's using various kinds of cameras, wearable activity monitors, and que...

Boston, MANA60 participantsNortheastern University

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NCT07119229Recruiting

A Multi Center Study Testing a New Implant for Adults With Severe Emphysema

A study taking place at multiple sites in the United States, Europe and Brazil to evaluate how well a new therapy for severe COPD/emphysema works, and how safe it is....

Boston, MANA60 participantsPulmair Medical, Inc.

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NCT04991831Recruiting

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease

The objectives of this study are to collect the long-term safety and effectiveness data of performing thalamotomy for tremor dominant Parkinson's Disease (TDPD) using the Exablate Neuro system....

Boston, MA50 participantsInSightec

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NCT07047807Recruiting

PDAC-PATHWAYS: A Digital Informational and Supportive Care App for Patients Initiating Neoadjuvant Therapy for Pancreatic Ductal Adenocarcinoma

This study aims to refine and pilot test PDAC-PATHWAYS, a digital informational and supportive care app for patients who are initiating neoadjuvant therapy for pancreatic ductal adenocarcinoma (PDAC)....

Boston, MANA50 participantsMassachusetts General Hospital

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NCT07005180Recruiting

Low-dose Carbon Monoxide (HBI-002) Trial to Evaluate Safety, Tolerability, PK, and Biomarkers in Parkinson's Disease

A phase 2a multicenter, randomized, double-blind, placebo-controlled multiple dose study to evaluate the safety, tolerability, pharmacokinetics, of HBI-002, an oral low-dose carbon monoxide (CO) liqui...

Boston, MAPHASE236 participantsHillhurst Biopharmaceuticals, Inc.

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NCT06602544Recruiting

Robotic Apparel to Prevent Freezing of Gait in Parkinson Disease

Freezing-of-gait (FoG) in Parkinson Disease (PD) is one of the most vivid and disturbing gait phenomena in neurology. Often described by patients as a feeling of "feet getting glued to the floor," FoG...

Boston, MANA20 participantsHarvard Medical School (HMS and HSDM)

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NCT04801108Recruiting

Combined Zephyr Valve System With Inter-lobar Fissure Completion for Lung Volume Reduction in Emphysema

The purpose of this protocol is to perform a pilot prospective randomized controlled clinical trial to evaluate the potential role of lung fissure completion strategy (experimental intervention) in ad...

Boston, MANA20 participantsBeth Israel Deaconess Medical Center

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NCT05257681Recruiting

Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction

The purpose of this protocol is to perform a pilot prospective controlled clinical trial to evaluate the potential role of lung fissure completion with pleural adhesiolysis strategy (experimental inte...

Boston, MANA20 participantsBeth Israel Deaconess Medical Center

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NCT06687837Recruiting

Treating Parkinson's Disease Through Transplantation of Autologous Stem Cell-Derived Dopaminergic Neurons

The goal of this clinical trial is to assess the safety and tolerability of the surgical transplantation of dopaminergic progenitor cells into the brains of participants with Parkinson's disease. The ...

Boston, MAPHASE18 participantsJeffrey S. Schweitzer, MD, PhD

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About Parkinsons Disease Clinical Trials in Boston

Parkinson's disease is a progressive nervous system disorder that affects movement, causing tremors, stiffness, and difficulty with balance. It results from the loss of dopamine-producing neurons in the brain. Treatment includes medications, deep brain stimulation, and emerging therapies targeting disease modification.

There are currently 20 parkinsons disease clinical trials recruiting participants in Boston, MA. These studies are seeking a combined 3,193 participants. Research is being sponsored by JHSPH Center for Clinical Trials, Temple University, Apreo Health, Inc. and 13 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Parkinsons Disease Clinical Trials in Boston — FAQ

Are there parkinsons disease clinical trials in Boston?

Yes, there are 20 parkinsons disease clinical trials currently recruiting in Boston, MA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What parkinsons disease treatments are being tested?

The 20 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for parkinsons disease.

Data updated October 20, 2026 from ClinicalTrials.gov