Boston, MASSACHUSETTS6 Active Studies

Colorectal Cancer Clinical Trials in Boston, MASSACHUSETTS

Find 6 actively recruiting colorectal cancer clinical trials in Boston, MASSACHUSETTS. Connect with local research sites and explore new treatment options.

6
Active Trials
6
Sponsors
1,290
Enrolling

Recruiting Colorectal Cancer Studies in Boston

RecruitingBoston, MASSACHUSETTSNCT03803553

Identification and Treatment Of Micrometastatic Disease in Stage III Colon Cancer

This research study is comparing two standard of care treatment options based on blood test results for participants who have metastatic colon cancer. The names of the potential treatments involved i...

400 participants
Massachusetts General Hospital
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RecruitingBoston, MASSACHUSETTSNCT06820463

A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

CRC is the third most common type of cancer diagnosed worldwide with developed countries at highest risk. The purpose of this study is to assess adverse events and change in disease activity when teli...

390 participants
AbbVie
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RecruitingBoston, MASSACHUSETTSNCT03659448

Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer

The performance of SGM-101, an intraoperative imaging agent, will be compared to that of standard "white light" visualization during surgical resections of colorectal cancer....

300 participants
Surgimab
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RecruitingBoston, MASSACHUSETTSNCT06792695

A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer

The main purpose of this study is to evaluate the safety and efficacy of novel study interventions and combinations in participants with Colorectal Cancer (CRC)....

120 participants
AstraZeneca
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RecruitingBoston, MASSACHUSETTSNCT03516708

Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer

The purpose of this research study is to evaluate epacadostat when given with routine radiation therapy and chemotherapy (capecitabine and oxaliplatin) to treat rectal cancer before routine surgery is...

49 participants
Washington University School of Medicine
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RecruitingBoston, MASSACHUSETTSNCT06412198

A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations

To learn if the drug combination of adagrasib, cetuximab, and cemiplimab can help to control metastatic CRC with KRAS G12C mutations....

31 participants
M.D. Anderson Cancer Center
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About Colorectal Cancer Clinical Trials in Boston

Colorectal cancer starts in the colon or rectum and is the third most common cancer diagnosed in both men and women. Early detection through screening significantly improves outcomes. Treatments include surgery, chemotherapy, radiation, and targeted therapies.

There are currently 6 colorectal cancer clinical trials recruiting participants in Boston, MASSACHUSETTS. These studies are seeking a combined 1,290 participants. Research is being sponsored by Massachusetts General Hospital, AbbVie, Surgimab and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Colorectal Cancer Clinical Trials in Boston — FAQ

Are there colorectal cancer clinical trials in Boston?

Yes, there are 6 colorectal cancer clinical trials currently recruiting in Boston, MASSACHUSETTS. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What colorectal cancer treatments are being tested?

The 6 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for colorectal cancer.

Data updated March 2, 2026 from ClinicalTrials.gov