Recruiting Diffuse Large B-Cell Lymphoma Studies in Boston
A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)
The purpose of this Phase 2/3, randomized, multisite, open-label, dose confirmation, and expansion study is to evaluate the safety, and efficacy of zilovertamab vedotin (ZV) in combination with standa...
Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
A multicenter, open-label Phase 2b study of selinexor (KPT-330) in participants with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) who have no therapeutic options of demonstrated cli...
Study of CTO1681 for the Prevention and Treatment of CRS in DLBCL Patients Receiving CAR T-Cell Therapy
This is an interventional study to evaluate the use of CTO1681 in preventing or reducing CAR T-cell-induced toxicities like cytokine release syndrome (CRS). This study will enroll adult patients with ...
Emapalumab Prevention of CAR-T Cell Associated Toxicities
This research study involves assessing the impact of emapalumab as preventative management of CAR-T related cytokine release syndrome in participants with Non-Hodgkin's lymphoma (NHL). The research s...
About Diffuse Large B-Cell Lymphoma Clinical Trials in Boston
Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma, accounting for about 30% of cases. It is an aggressive lymphoma that grows rapidly. Treatment usually involves chemoimmunotherapy, with CAR-T cell therapy for relapsed cases.
There are currently 4 diffuse large b-cell lymphoma clinical trials recruiting participants in Boston, MASSACHUSETTS. These studies are seeking a combined 616 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Karyopharm Therapeutics Inc, CytoAgents, Inc. and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.
Diffuse Large B-Cell Lymphoma Clinical Trials in Boston — FAQ
Are there diffuse large b-cell lymphoma clinical trials in Boston?
Yes, there are 4 diffuse large b-cell lymphoma clinical trials currently recruiting in Boston, MASSACHUSETTS. Browse the studies on this page to find one that fits.
How do I join a clinical trial in Boston?
Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.
Are clinical trials in Boston free?
Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.
What diffuse large b-cell lymphoma treatments are being tested?
The 4 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for diffuse large b-cell lymphoma.
Data updated March 2, 2026 from ClinicalTrials.gov