Boston, MASSACHUSETTS6 Active Studies

Endometrial Cancer Clinical Trials in Boston, MASSACHUSETTS

Find 6 actively recruiting endometrial cancer clinical trials in Boston, MASSACHUSETTS. Connect with local research sites and explore new treatment options.

6
Active Trials
5
Sponsors
504
Enrolling

Recruiting Endometrial Cancer Studies in Boston

RecruitingBoston, MASSACHUSETTSNCT03675893

RESOLVE: Abemaciclib + Letrozole +/- Metformin, Zotatifin, or Gedatolisib in Endometrial or Low-Grade Serous Ovarian Cancer

This research study is studying a combination of targeted therapies as a possible treatment for estrogen-receptor positive (ER+) endometrial cancer and low-grade serous ovarian cancer. The drugs invo...

180 participants
Dana-Farber Cancer Institute
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RecruitingBoston, MASSACHUSETTSNCT04486352

A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer

This is a Phase IB/II multi-cohort study designed to evaluate the efficacy and safety of targeted agents with or without cancer immune checkpoint therapy with atezolizumab in participant with recurren...

148 participants
Alliance Foundation Trials, LLC.
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RecruitingBoston, MASSACHUSETTSNCT06366347

ALPINE: Maintenance Letrozole/Abemaciclib vs Pembrolizumab

A standard treatment for endometrial cancer is chemotherapy and pembrolizumab together followed by pembrolizumab maintenance for two years. This treatment regimen has shown benefit in terms of delayin...

76 participants
Dana-Farber Cancer Institute
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RecruitingBoston, MASSACHUSETTSNCT02491099

A Phase II Evaluation of Afatinib in Patients With Persistent or Recurrent HER2-positive Uterine Serous Carcinoma

Primary Objective: To assess the activity of Afatinib in patients with persistent or recurrent uterine serous carcinoma overexpressing HER2/neu with the frequency of patients who survive progression-f...

50 participants
Yale University
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RecruitingBoston, MASSACHUSETTSNCT06369155

Azenosertib in Uterine Serous Carcinoma: Biomarker Study

This research study is being done to investigate how Azenosertib affects tumor cells of persistent or recurrent uterine serous carcinoma. The name of the study drug involved in this study is: -Azeno...

25 participants
Joyce Liu, MD
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RecruitingBoston, MASSACHUSETTSNCT06518564

Avelumab and M1774 in ARID1A-mutated Endometrial Cancer

The purpose of this research study is to see if the combination of study drugs avelumab and M1774 is effective and safe for participants with endometrial cancer. The names of the study drugs involved...

25 participants
Panagiotis Konstantinopoulos, MD, PhD
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About Endometrial Cancer Clinical Trials in Boston

Endometrial cancer begins in the lining of the uterus and is the most common gynecologic cancer. It is often detected early due to abnormal bleeding symptoms. Treatment typically involves surgery, with radiation, chemotherapy, or hormone therapy for advanced cases.

There are currently 6 endometrial cancer clinical trials recruiting participants in Boston, MASSACHUSETTS. These studies are seeking a combined 504 participants. Research is being sponsored by Dana-Farber Cancer Institute, Alliance Foundation Trials, LLC., Yale University and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Endometrial Cancer Clinical Trials in Boston — FAQ

Are there endometrial cancer clinical trials in Boston?

Yes, there are 6 endometrial cancer clinical trials currently recruiting in Boston, MASSACHUSETTS. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What endometrial cancer treatments are being tested?

The 6 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for endometrial cancer.

Data updated March 2, 2026 from ClinicalTrials.gov