Boston, MASSACHUSETTS4 Active Studies

Non-Small Cell Lung Cancer Clinical Trials in Boston, MASSACHUSETTS

Find 4 actively recruiting non-small cell lung cancer clinical trials in Boston, MASSACHUSETTS. Connect with local research sites and explore new treatment options.

4
Active Trials
4
Sponsors
1,644
Enrolling

Recruiting Non-Small Cell Lung Cancer Studies in Boston

RecruitingBoston, MASSACHUSETTSNCT05384626

A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

Phase 1/2, dose escalation and expansion study designed to evaluate the safety and tolerability of neladalkib (NVL-655), determine the recommended phase 2 dose (RP2D), and evaluate the antitumor activ...

840 participants
Nuvalent Inc.
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RecruitingBoston, MASSACHUSETTSNCT04165070

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

The purpose of this study is to assess the efficacy and safety of pembrolizumab (MK-3475) with or without chemotherapy in combination with vibostolimab (MK-7684), boserolimab (MK-5890), MK-4830, MK-04...

450 participants
Merck Sharp & Dohme LLC
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RecruitingBoston, MASSACHUSETTSNCT05967689

A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation.

The purpose of this study is to evaluate the safety, efficacy and pharmacokinetics (PK) of zipalertinib in participants with locally advanced or metastatic Non-Small Cell Lung Cancer (NSCLC) harboring...

224 participants
Taiho Oncology, Inc.
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RecruitingBoston, MASSACHUSETTSNCT06855771

A Study of BMS-986504 in Participants With Pre-treated Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) With Homozygous MTAP Deletion (MountainTAP-9)

The purpose of this study is to evaluate the safety and efficacy of BMS-986504 monotherapy in participants with advanced or metastatic Non-small Cell Lung Cancer (NSCLC) with homozygous MTAP deletion ...

130 participants
Bristol-Myers Squibb
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About Non-Small Cell Lung Cancer Clinical Trials in Boston

Non-small cell lung cancer (NSCLC) accounts for about 85% of all lung cancers. Subtypes include adenocarcinoma, squamous cell carcinoma, and large cell carcinoma. Treatment has been transformed by targeted therapies and immunotherapy based on specific genetic markers.

There are currently 4 non-small cell lung cancer clinical trials recruiting participants in Boston, MASSACHUSETTS. These studies are seeking a combined 1,644 participants. Research is being sponsored by Nuvalent Inc., Merck Sharp & Dohme LLC, Taiho Oncology, Inc. and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Non-Small Cell Lung Cancer Clinical Trials in Boston — FAQ

Are there non-small cell lung cancer clinical trials in Boston?

Yes, there are 4 non-small cell lung cancer clinical trials currently recruiting in Boston, MASSACHUSETTS. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What non-small cell lung cancer treatments are being tested?

The 4 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for non-small cell lung cancer.

Data updated March 2, 2026 from ClinicalTrials.gov