Boston, MASSACHUSETTS4 Active Studies

Triple Negative Breast Cancer Clinical Trials in Boston, MASSACHUSETTS

Find 4 actively recruiting triple negative breast cancer clinical trials in Boston, MASSACHUSETTS. Connect with local research sites and explore new treatment options.

4
Active Trials
3
Sponsors
560
Enrolling

Recruiting Triple Negative Breast Cancer Studies in Boston

RecruitingBoston, MASSACHUSETTSNCT04230109

Sacituzumab Govitecan In TNBC

This research study is studying to evaluate sacituzumab govitecan for individuals with localized triple negative breast cancer (TNBC) The names of the study drugs involved in this study is: * Sacitu...

260 participants
Massachusetts General Hospital
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RecruitingBoston, MASSACHUSETTSNCT03971409

Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer

This phase II trial studies how well the combination of avelumab with liposomal doxorubicin with or without binimetinib, or the combination of avelumab with sacituzumab govitecan works in treating pat...

150 participants
Laura Huppert, MD, BA
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RecruitingBoston, MASSACHUSETTSNCT04468061

Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

This research study involves testing the safety and efficacy of an investigational intervention for patients with triple-negative breast cancer (TNBC) that has spread, or metastasized, to other parts ...

110 participants
Dana-Farber Cancer Institute
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RecruitingBoston, MASSACHUSETTSNCT04434040

Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)

The purpose of this study is to determine if a combination of two drugs sacituzumab govitecan and atezolizumab works as a treatment for residual cancer in the breast or lymph nodes and have circulatin...

40 participants
Dana-Farber Cancer Institute
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About Triple Negative Breast Cancer Clinical Trials in Boston

Triple-negative breast cancer (TNBC) lacks estrogen receptors, progesterone receptors, and excess HER2 protein, limiting targeted treatment options. It accounts for about 10-15% of breast cancers and tends to be more aggressive. Active research focuses on immunotherapy and novel drug combinations.

There are currently 4 triple negative breast cancer clinical trials recruiting participants in Boston, MASSACHUSETTS. These studies are seeking a combined 560 participants. Research is being sponsored by Massachusetts General Hospital, Laura Huppert, MD, BA, Dana-Farber Cancer Institute. Clinical trial participation is free and participants receive study-related medical care at no cost.

Triple Negative Breast Cancer Clinical Trials in Boston — FAQ

Are there triple negative breast cancer clinical trials in Boston?

Yes, there are 4 triple negative breast cancer clinical trials currently recruiting in Boston, MASSACHUSETTS. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What triple negative breast cancer treatments are being tested?

The 4 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for triple negative breast cancer.

Data updated March 2, 2026 from ClinicalTrials.gov