17 HIV AIDS Clinical Trials in Boston, NY (2026)

Q: How do I join a clinical trial in Boston?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you.

Recruiting HIV AIDS Studies in Boston

NCT02140255Recruiting

Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

The study will explore the effects of early intensive antiretroviral therapy (ART) with or without a broadly neutralizing antibody (bNAb) on achieving HIV remission (HIV RNA below the limit of detecti...

Boston, NY1,120 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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NCT05503173Recruiting

Telehealth for Pain and Unhealthy Drinking Among PLWH

This randomized controlled trial is a between-groups design to compare the Motivational and Cognitive Behavioral Management for Alcohol and Pain (MCBMAP) Intervention to a Brief Advice and Information...

Boston, NY385 participantsBoston University

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NCT05241990Recruiting

Practice Facilitation as a Strategy to Improve Alcohol Treatment Adoption and Implementation in HIV Care

Despite availability of evidence-based alcohol reduction interventions (EBI), unhealthy alcohol use remains a barrier to HIV medication adherence, viral suppression and retention in HIV care and conse...

Boston, NY300 participantsJohns Hopkins University

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NCT06088277Recruiting

Texting to Reduce Human Immunodeficiency Virus (HIV) Risk

This is a 3-year study to test the efficacy of a text message-based intervention program. Dental patients at 4 community health centers (n= 266) will be randomized to receive either text messages (TMs...

Boston, NY266 participantsBoston University

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NCT05934305Recruiting

Mitigating the Impact of Stigma and Shame Among People Living With HIV and Substance Use Disorders

People living with HIV and substance use disorders (SUDs) are less likely to be virally suppressed, which can lead to HIV transmission and negative health outcomes. This hybrid type 1 study will asses...

Boston, NY256 participantsBoston University

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NCT06263426Recruiting

Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)

This research is being done to better understand rejection in transplant recipients with HIV who receive kidneys from donors with vs without HIV....

Boston, NY200 participantsJohns Hopkins University

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NCT06812494Recruiting

A Study of VRC07-523LS, PGT121.414.LS, and PGDM1400LS Broadly Neutralizing Monoclonal Antibodies Given Intravenously in Adult Participants Without HIV

HVTN 206/HPTN 114 is a randomized, double blind, controlled, phase 2 clinical trial to evaluate the safety, tolerability, pharmacokinetics, and neutralization of VRC07-523LS, PGT121.414.LS, and PGDM14...

Boston, NY200 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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NCT06856174Recruiting

Menopausal HT for Women Living With HIV (HoT)

Women living with HIV have been shown to experience more frequent and severe hot flashes and night sweats (collectively known as vasomotor symptoms) as compared to women living without HIV. This corre...

Boston, NY105 participantsAdvancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

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NCT06554717Recruiting

Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV

People with HIV experience earlier impairments in physical function compared to people in the general population. They also exhibit an earlier presentation and more rapid development of frailty, a mul...

Boston, NY100 participantsMassachusetts General Hospital

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NCT07199335Recruiting

Long-acting Cabotegravir Injectable Pre-exposure Prophylaxis for People Who Inject Drugs

The goal of this study is to determine the feasibility and impact of delivering long-acting injectable cabotegravir HIV pre-exposure prophylaxis and suite of support services to adults who inject non-...

Boston, NY100 participantsMassachusetts General Hospital

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NCT07390955Recruiting

A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1

This study is testing a lab-made antibody called ePGT121v1-LS that targets a specific part of HIV. Researchers will give it by vein (IV) and under the skin (SC), both on its own and together with two ...

Boston, NY83 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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NCT06843902Recruiting

Improving Coronary Vascular Health in Women

Women with HIV have an increased risk of having a myocardial infarction (heart attack) as compared to women without HIV. One of the mechanisms underlying the increased risk of myocardial infarction am...

Boston, NY80 participantsMassachusetts General Hospital

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NCT06001814Recruiting

Mindfulness and Behavior Change to Improve Cardiovascular Health of Older People With HIV

Older people with HIV (OPWH) are disproportionately impacted by cardiovascular disease (CVD) attributable to behavioral risk factors, and chronic HIV immune dysregulation resulting inflammation. Syste...

Boston, NY50 participantsMassachusetts General Hospital

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NCT06796686Recruiting

Clinical Trial to Evaluate the Safety and Immunogenicity of a Priming Regimen of 426c.Mod.Core-C4b Followed by HxB2.WT.Core-C4b Boosts, Both Adjuvanted With 3M-052 AF + Alum, in Adult Participants Without HIV and in Overall Good Health

This is a partially randomized, open-label phase 1 study to evaluate the safety and immunogenicity of a priming regimen of 426c.Mod.Core-C4b adjuvanted with 3M-052 AF + Alum followed by boosts with Hx...

Boston, NY42 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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NCT07390474Recruiting

Clinical Trial to Evaluate the Safety and Immunogenicity of the V2 Apex-Directed Immunogens DV201P-RNA and DV202B1-RNA in Adult Participants Without HIV

This is a phase 1, multicenter, open-label, dose escalation, first-in-human (FIH) trial to evaluate the safety and immunogenicity of DV201P-RNA and DV202B1-RNA, immunogens designed to induce HIV-1 env...

Boston, NY40 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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NCT06665646Recruiting

Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706

The clinical schedule will consist of 3 injections of CD40.HIVRI.Env (VRIPRO) at weeks 0, 4, and 24.40 volunteers without HIV and in overall good health, aged 18 to 60 years, who previously participat...

Boston, NY40 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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NCT06071767Recruiting

Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1

The purpose of this study is to evaluate the safety, tolerability, and efficacy of therapeutic vaccination with chimpanzee adenovirus ChAdOx1- and poxvirus modified vaccinia Ankara (MVA)-vectored cons...

Boston, NY36 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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About HIV AIDS Clinical Trials in Boston

HIV (human immunodeficiency virus) attacks the immune system and, if untreated, can lead to AIDS (acquired immunodeficiency syndrome). Antiretroviral therapy (ART) can control the virus and prevent transmission. Research continues to pursue a functional cure, long-acting therapies, and preventive vaccines.

There are currently 17 hiv aids clinical trials recruiting participants in Boston, NY. These studies are seeking a combined 3,403 participants. Research is being sponsored by National Institute of Allergy and Infectious Diseases (NIAID), Boston University, Johns Hopkins University and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

HIV AIDS Clinical Trials in Boston — FAQ

Are there hiv aids clinical trials in Boston?

Yes, there are 17 hiv aids clinical trials currently recruiting in Boston, NY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What hiv aids treatments are being tested?

The 17 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for hiv aids.

Data updated July 13, 2026 from ClinicalTrials.gov