15 Ankylosing Spondylitis Clinical Trials in Chapel Hill, NC (2026)

Q: How do I join a clinical trial in Chapel Hill?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Chapel Hill research site will contact you.

Recruiting Ankylosing Spondylitis Studies in Chapel Hill

NCT00345930Recruiting

DILIN - Prospective Study

The purpose of this study is to identify individuals who have suffered a liver injury arising as an idiosyncratic reaction to a prescription drug or a complementary and alternative medicine. Recently ...

Chapel Hill, NC4,000 participantsDuke University

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NCT07214610Recruiting

Integrating Biological, Clinical, and Behavioral Factors to Improve Breast Cancer Outcomes - Carolina Breast Cancer Study

Phase 4 of the Carolina Breast Cancer Study (CBCS4) builds on prior phases that examined molecular and epidemiologic differences in breast cancer types and outcomes. Previous findings showed that cert...

Chapel Hill, NCNA3,300 participantsUNC Lineberger Comprehensive Cancer Center

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NCT07052942Recruiting

Individualizing Treatment for Asthma in Primary Care (Full Study)

While asthma therapy is becoming more individualized based on asthma phenotypes, more research is needed to tailor newer therapies to individuals. Inhaled corticosteroid (ICS) medications are the foun...

Chapel Hill, NCPHASE43,200 participantsDARTNet Institute

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NCT05997875Recruiting

Transforming Hemodialysis-Related Vascular Access Education

The focus of this study is on vascular access for hemodialysis. This is a randomized clinical trial testing 3 educational approaches to help patients with advanced chronic kidney disease prepare for p...

Chapel Hill, NCNA360 participantsUniversity of Pennsylvania

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NCT06610539Recruiting

PAS 1ml Magtrace® for Sentinel Lymph Node Biopsy in Breast Cancer Patients

The purpose of this study is to provide prospective evidence in the US population of the frequency of skin discoloration and Sentinel Lymph Node detection rate in patients who have recevied Magtrace f...

Chapel Hill, NC184 participantsEndomagnetics Ltd.

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NCT07290569Recruiting

Dose Ranging Study of ORKA-001 in Patients With Moderate-to-Severe Plaque Psoriasis

This is a multicenter, randomized, double-blinded, placebo-controlled, dose-range finding study to evaluate the efficacy and safety of ORKA-001 in adult participants with moderate-to-severe plaque pso...

Chapel Hill, NCPHASE2160 participantsOruka Therapeutics, Inc.

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NCT07322406Recruiting

Kaempferol Absorption and Pharmacokinetics Evaluation

This study is a multi-site clinical trial designed to evaluate how the body absorbs and processes Kaempferol, a naturally occurring compound found in many plant-based foods. The primary purpose of the...

Chapel Hill, NCNA120 participantsUniversity of Pittsburgh

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NCT07025785Recruiting

Molecular Residual Disease Assessment in a Representative Diverse Population of Patients With Early-stage Breast Cancer

The purpose of this study is to determine how circulating tumor DNA (ctDNA), a sign of minimal residual disease (MRD), is detectable after surgery in patients with early HR+/HER2- breast cancer that h...

Chapel Hill, NCNA100 participantsUNC Lineberger Comprehensive Cancer Center

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NCT06727773Recruiting

Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer

This randomized, placebo-controlled trial aims to assess the feasibility, acceptability, and preliminary efficacy of memantine and the University of Carolina (UNC)'s Get Real \& Heel cancer exercise p...

Chapel Hill, NCPHASE290 participantsUNC Lineberger Comprehensive Cancer Center

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NCT07391605Recruiting

Descartes-08 in Autoantibody Myositis

This is a randomized, double-blind, placebo-controlled phase 2 study to evaluate the efficacy, safety and tolerability of an autologous T-cells expressing a chimeric antigen receptor (CAR) directed to...

Chapel Hill, NCPHASE260 participantsCartesian Therapeutics

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NCT04099290Recruiting

Circulating Tumor DNA (ctDNA) in Locally Advanced Head and Neck Squamous Cell Carcinoma

Circulating tumor DNA (ctDNA) is a blood-based test that measures dying or dead cancer cells that are already circulating in the blood. In this study, the investigators will enroll patients who are pl...

Chapel Hill, NC50 participantsUNC Lineberger Comprehensive Cancer Center

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NCT06860880Recruiting

Combating Cancer-Related Fatigue: A Personalized Supportive Care Program

This health services study will assess a multidisciplinary intervention program directed at fatigue mitigation among patients diagnosed with indolent lymphomas. Specifically, 30 subjects with chronic ...

Chapel Hill, NCNA40 participantsUNC Lineberger Comprehensive Cancer Center

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NCT07101640Recruiting

PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia

The purpose of the study is to learn how safe montelukast may be in premature infants at significant risk for Bronchopulmonary Dysplasia (BPD) and to determine how much and how quickly montelukast mov...

Chapel Hill, NCPHASE128 participantsDuke University

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NCT06252545Recruiting

Promoting CT Engagement for Pancreatic Cancer With App

To develop a culturally tailored informational mobile application and test whether it will increase participation among Black pancreatic cancer subjects in clinical trial discussions with their care t...

Chapel Hill, NCNA26 participantsUNC Lineberger Comprehensive Cancer Center

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NCT07337902Recruiting

Comparing Over the Counter Pain Medicines for Discomfort in Crohn's Disease (AVID-CD)

The purpose of this pilot study is to prepare for a larger study that will compare the effectiveness and safety of two common pain medications, ibuprofen and acetaminophen, to help treat period cramps...

Chapel Hill, NCNA24 participantsUniversity of North Carolina, Chapel Hill

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About Ankylosing Spondylitis Clinical Trials in Chapel Hill

Ankylosing spondylitis is a chronic inflammatory disease primarily affecting the spine and sacroiliac joints, causing pain, stiffness, and potentially spinal fusion. It typically begins in early adulthood. Treatment includes NSAIDs, biologics (TNF and IL-17 inhibitors), and physical therapy.

There are currently 15 ankylosing spondylitis clinical trials recruiting participants in Chapel Hill, NC. These studies are seeking a combined 11,742 participants. Research is being sponsored by Duke University, UNC Lineberger Comprehensive Cancer Center, DARTNet Institute and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ankylosing Spondylitis Clinical Trials in Chapel Hill — FAQ

Are there ankylosing spondylitis clinical trials in Chapel Hill?

Yes, there are 15 ankylosing spondylitis clinical trials currently recruiting in Chapel Hill, NC. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Chapel Hill?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Chapel Hill research site will contact you about next steps.

Are clinical trials in Chapel Hill free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Chapel Hill studies also compensate for your time and travel.

What ankylosing spondylitis treatments are being tested?

The 15 active trials in Chapel Hill are testing new therapies including novel drugs, biologics, and treatment approaches for ankylosing spondylitis.

Data updated July 18, 2026 from ClinicalTrials.gov