61 Interstitial Cystitis Clinical Trials in Chicago, IL (2026)

Q: How do I join a clinical trial in Chicago?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Chicago research site will contact you.

Recruiting Interstitial Cystitis Studies in Chicago

NCT01522183Recruiting

Atypical Hemolytic-Uremic Syndrome (aHUS) Registry

Post-marketing safety data on patients treated and untreated with eculizumab or ravulizumab....

Chicago, IL3,000 participantsAlexion Pharmaceuticals, Inc.

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NCT06970977Recruiting

CRS Questionnaire Validation Project

The 'CRS validation project' consists of a joint effort of 32 medical centers in Europe, the USA, and South Africa to carry out the validation of 2 novel questionnaires designated to measure self-perc...

Chicago, IL1,000 participantsThe European Forum for Research and Education in Allergy and Airway Diseases

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NCT01241305Recruiting

One-Time DNA Study for Vasculitis

The purpose of this study is to identify genes that increase the risk of developing vasculitis, a group of severe diseases that feature inflammation of blood vessels. Results of these studies will pro...

Chicago, IL1,000 participantsUniversity of Pennsylvania

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NCT04629014Recruiting

Prospective Multisite Study of Quality of Life in Pediatric Intestinal Failure

This study proposes to quantify and describe the quality of life of children with intestinal failure, and to identify the medical and socio-economic factors that impact this quality of life, using dat...

Chicago, IL750 participantsBoston Children's Hospital

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NCT06870812Recruiting

Rapid Evacuation and Access of Cerebral Hemorrhage Trial

The main purpose of this study is to compare patients with a deep bleed in the brain undergoing surgery to patients receiving routine medical care. The standard treatment involves admission to the Int...

Chicago, ILNA600 participantsEmory University

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NCT05199532Recruiting

Eosinophilic Gastrointestinal Disorders Registry

The purpose of this study is to learn more about Eosinophilic Gastrointestinal Disorders (EGIDs). With this registry we hope to find out more about the symptoms that patients have during their treatme...

Chicago, IL500 participantsAnn & Robert H Lurie Children's Hospital of Chicago

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NCT05365815Recruiting

Melanated Group Midwifery Care (MGMC)

This study is being conducted to determine if a multi-level intervention for delivering maternity care can improve patient trust and engagement among Black birthing people....

Chicago, ILNA432 participantsUniversity of Illinois at Chicago

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NCT07115940Recruiting

Medical Management With Endovascular Thrombectomy Versus Medical Management Alone in Patients Presenting Beyond 24 Hours of Last Known Well

SELECT LATE trial aims to evaluate if addition of endovascular thrombectomy to medical management in patients presenting with acute ischemic stroke and a proximal large vessel occlusion in the anterio...

Chicago, ILNA408 participantsAmrou Sarraj

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NCT06390345Recruiting

Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention

The investigators will conduct a Type I hybrid effectiveness-implementation study to test an integrated telehealth intervention among 400 overweight and obese patients with Chronic Obstructive Pulmona...

Chicago, ILNA400 participantsSeattle Institute for Biomedical and Clinical Research

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NCT06545331Recruiting

Study of XB010 in Subjects With Solid Tumors

This is a FIH study is to evaluate the safety, tolerability, PK, immunogenicity, and preliminary antitumor activity of XB010 as a single agent and in combination with pembrolizumab in subjects with lo...

Chicago, ILPHASE1396 participantsExelixis

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NCT07227155Recruiting

The HOPE Biobank Resource (BMT CTN 2402 HOPE)

A prospective, multicenter study that will establish a repository of biospecimens and clinical data from patients undergoing hematopoietic stem cell transplant (HCT) or gene therapy (GT) for treatment...

Chicago, IL375 participantsMedical College of Wisconsin

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NCT06883045Recruiting

A Novel mHealth Intervention to Improve Outcomes of Children With Medical Complexity

Children with medical complexity (CMC) are the most vulnerable of children with chronic diseases, who have complex, multisystem chronic diseases affecting ≥3 organ systems, severe functional limitatio...

Chicago, ILNA360 participantsUniversity of Utah

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NCT06561295Recruiting

Optimal Timing for Spontaneous Breathing Trials

This study aims to explore how the timing of Spontaneous Breathing Trials (SBTs) affects recovery in adult patients who are on mechanical ventilation in the ICU. SBTs are tests used to determine if a ...

Chicago, ILNA348 participantsRush University Medical Center

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NCT06740383Recruiting

Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services

The Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services (BICEPS) study aims to understand the early stages of psychotic disorders like Schizophrenia, Schizoaffective Disorder, and Bi...

Chicago, IL320 participantsBeth Israel Deaconess Medical Center

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NCT06661850Recruiting

Examination of Nociscan Impact on Discogenic Low Back Pain Surgical Outcomes

This study is looking into how safe and useful NOCISCAN is. NOCISCAN is a software as a Service (SaaS) tool that uses Magnetic Resonance (MR) spectroscopy. Nociscan (instead of 'It') leverages MRS to ...

Chicago, IL300 participantsAclarion

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NCT07076849Recruiting

Probiotic Supplementation in Optimizing Iron and Hematological Status Among Pregnant Females

Maternal iron deficiency (ID) and iron deficiency anemia (IDA) is associated with maternal and infant mortality, spontaneous preterm birth, maternal postpartum hemorrhage, and neurocognitive defects i...

Chicago, ILPHASE2250 participantsUniversity of Illinois at Chicago

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NCT04830137Recruiting

A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies

This is a first-in-human Phase 1a/1b multicenter, open-label oncology study designed to evaluate the safety and anti-cancer activity of NX-2127 in patients with advanced B-cell malignancies....

Chicago, ILPHASE1248 participantsNurix Therapeutics, Inc.

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NCT04054310Recruiting

Non-Invasive Quantification of Liver Health in NASH (N-QUAN)

To evaluate, in patients with suspected NASH referred for liver biopsy, the diagnostic performance of CT1 at discriminating those with NAS≥4 \& F≥2 from those without....

Chicago, ILNA225 participantsPerspectum

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NCT06296186Recruiting

Massed Prolonged Exposure for PTSD in Substance Use Treatment

The goal of this clinical trial is to learn if receiving Prolonged Exposure Therapy for PTSD in massed format (multiple sessions weekly) is as effective as receiving it with sessions once per week amo...

Chicago, ILNA200 participantsVeterans Medical Research Foundation

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NCT04194996Recruiting

Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0

Multi-center, prospective, non-randomized study to evaluate outcomes of surgically treated patients with adult cervical spinal deformity....

Chicago, IL200 participantsInternational Spine Study Group Foundation

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NCT07195734Recruiting

Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

This phase II trial tests the addition of chemotherapy, with carboplatin and paclitaxel, or chemo-immunotherapy, with carboplatin, paclitaxel and cemiplimab to standard salvage surgery followed by pos...

Chicago, ILPHASE2180 participantsNational Cancer Institute (NCI)

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NCT04068012Recruiting

Clinical Decision Support Tool in PARDS Pilot Study

Previous clinical trials in adults with acute respiratory distress syndrome (ARDS) have demonstrated that ventilator management choices can improve Intensive Care Unit (ICU) mortality and shorten time...

Chicago, ILNA180 participantsChildren's Hospital Los Angeles

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NCT07023614Recruiting

A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

FORTITUDE-HCM is a global, multicenter, double-blind, parallel-group, placebo-controlled Phase 2b study that will assess the efficacy and safety of ninerafaxstat compared to placebo on top of Standard...

Chicago, ILPHASE2165 participantsImbria Pharmaceuticals, Inc.

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NCT07277660Recruiting

A Dose-ranging Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Galvokimig in Adult Study Participants With Atopic Dermatitis

The purpose of the study is to evaluate the dose-response relationship of galvokimig compared with placebo in study participants with moderate-to-severe atopic dermatitis (AtD)....

Chicago, ILPHASE2160 participantsUCB Biopharma SRL

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NCT05294042Recruiting

Patient Navigators for Children's Community Mental Health Services in High Poverty Urban Communities

The purpose is to study a model of mental health navigation for African American and Latinx children (0-14 years) in high poverty urban communities focused on reducing key parental attitudinal barrier...

Chicago, ILNA154 participantsUniversity of Illinois at Chicago

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NCT06239116Recruiting

A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment

The purpose of this study is to evaluate the safety, tolerability, and PK of RM-718 in healthy subjects with obesity and in patients with MC4R Pathway Impairment...

Chicago, ILPHASE1150 participantsRhythm Pharmaceuticals, Inc.

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NCT07078383Recruiting

A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta

The Goal of this Clinical Study is to evaluate the safety and effectiveness of the Rapidlink device in the repair or replacement of the supra-aortic vessels during open surgical repair of aortic disea...

Chicago, ILNA150 participantsVascutek Ltd.

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NCT06879041Recruiting

A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer

The main purpose of the study is to assess the safety and tolerability of AZD2284, AZD2287, and AZD2275....

Chicago, ILPHASE1136 participantsAstraZeneca

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NCT07282418Recruiting

Behavioral Economic Attributes of Recreation

Risk for developing and dying from heart disease, type 2 diabetes, stroke, and other cardiometabolic conditions is strongly influenced by behavioral risk factors, including poor diet, physical inactiv...

Chicago, ILPHASE1120 participantsRush University Medical Center

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NCT06827990Recruiting

GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections

To assess the safety and effectiveness of the ASG device in the treatment of de novo Type A aortic dissections....

Chicago, ILNA112 participantsW.L.Gore & Associates

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NCT06996379Recruiting

J-Tip Use for Paracentesis in Adults With Ascites

The purpose of this clinical trial is to evaluate the level of comfort adult patients with cirrhosis of the liver and ascites presenting to Northwestern Memorial Hospital experience during a bedside a...

Chicago, ILNA110 participantsNorthwestern University

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NCT04914507Recruiting

A Prospective Analysis of Long-Term Clinical Outcomes and 3D Spine Growth in Anterior Vertebral Body Tethering

Anterior vertebral body tethering (AVBT) is a novel, minimally invasive, growth modulation technique that was recently approved by the FDA under a Humanitarian Device Exemption (HDE). The goal of AVBT...

Chicago, ILNA106 participantsPediatric Spine Foundation

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NCT06138873Recruiting

Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy

Over the last decade, radiofrequency catheter ablation (RFCA) has become an established treatment for ventricular arrhythmias (VA). Due to the challenging nature of visualizing lesion formation in rea...

Chicago, ILNA100 participantsRush University Medical Center

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NCT06359652Recruiting

Get Fit for Function

The purpose of this study will be to implement and evaluate a prehab program for pre-frail and frail adults who need to undergo thoracic surgery. The study team hypothesizes using an implementation fr...

Chicago, ILNA100 participantsUniversity of Chicago

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NCT05432479Recruiting

Study to Evaluate the Efficacy of a Probiotic in Infantile Colic Symptoms Relief

This study evaluates the efficacy of single strain probiotic administered in a form of a sachet in the treatment of infant colic in infants 3-12 weeks old....

Chicago, ILNA80 participantsThe Archer-Daniels-Midland Company

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NCT06925542Recruiting

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

This is a single-arm, open-label, multicenter, ascending dose Phase 1 study evaluating the safety and preliminary efficacy of CTX112 in adult subjects with refractory autoimmune diseases, including ac...

Chicago, ILPHASE180 participantsCRISPR Therapeutics

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NCT06118528Recruiting

EAT: A Reliable Eating Assessment Technology for Free-living Individuals

This study utilizes a small, privacy-conscious wearable device intended to monitor human behaviors. The device is worn around the neck, capturing the wearer's head and upper torso within its field of ...

Chicago, ILNA72 participantsNorthwestern University

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NCT06994676Recruiting

A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias

Study CBX-250-001 is a Phase 1, open-label, dose-escalation study of CBX-250 in participants with relapsed/refractory AML, HR-MDS, CMML, and CML. Participants aged ≥ 12 years are planned to be enrolle...

Chicago, ILPHASE172 participantsCrossbow Therapeutics, Inc.

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NCT07085104Recruiting

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

This is a first-in-human, single-arm, open-label study evaluating the safety, tolerability, and preliminary efficacy of ALLO-329 in adults with autoimmune diseases: systemic lupus erythematosus (SLE) ...

Chicago, ILPHASE166 participantsAllogene Therapeutics

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NCT06336447Recruiting

VR and Cooled Genicular Nerve Radio Frequency Ablation for Chronic Knee Pain

This study will examine the impact of virtual reality used in conjunction with sedation compared to sedation alone in patients undergoing watervcooled genicular nerve ablations for chronic knee pain. ...

Chicago, ILNA62 participantsNorthwestern University

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NCT06589362Recruiting

Noninvasive Vagal Nerve Stimulation and Cognitive Rehabilitation

The purpose of this study is to examine the feasibility and preliminary efficacy of using transcutaneous auricular vagus nerve stimulation (tVNS) to enhance cognitive recovery in patients with mild-mo...

Chicago, ILNA60 participantsShirley Ryan AbilityLab

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NCT05427695Recruiting

Topical Probiotic Sinus Irrigations for Treating Chronic Sinusitis

The purpose of this randomized study will be to determine whether topical probiotic sinus irrigations are more effective compared to saline sinus irrigation controls in the treatment of active CRS in ...

Chicago, ILPHASE260 participantsUniversity of Illinois at Chicago

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NCT07219654Recruiting

Efficacy and Safety Study of TPX-115 on Partial-thickness Rotator Cuff Tear

The goal of this study is to evaluate the efficacy and safety of allogeneic dermal fibroblasts (TPX-115) compared to placebo in patients with Partial-Thickness Rotator Cuff Tear(PTRCT). Primary endpo...

Chicago, ILPHASE260 participantsTego Science, Inc.

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NCT06725108Recruiting

Hemodynamic ABI Monitor

The goal of this observational study is to explore the relationship of heart function with the course and outcomes after traumatic brain injuries and nontraumatic intracerebral hemorrhage. The goal is...

Chicago, IL50 participantsUniversity of Chicago

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NCT06446661Recruiting

Using Text Messages to Improve Oral Chemotherapy for Adolescents and Adults With Acute Lymphoblastic Leukemia

This is a single center 2-phase study to assess effects of using text messages on adherence to oral chemotherapy for patients with acute lymphoblastic leukemia (ALL) or T-cell lymphoblastic lymphoma....

Chicago, ILNA48 participantsUniversity of Chicago

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NCT05283330Recruiting

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

A Phase 1 Open-Label, First-in-human, Dose Escalation and Expansion Study to Determine the Safety, Tolerability, Dosimetry, Pharmacokinetics, and Preliminary Efficacy of 212Pb-DOTAM-GRPR1 in Adult Par...

Chicago, ILPHASE148 participantsOrano Med Theranostics, SAS

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NCT05172245Recruiting

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

This phase I/Ib trial tests the safety and best dose of ipatasertib in combination with the usual treatment approach using chemotherapy together with radiation therapy ("chemo-radiation") in patients ...

Chicago, ILPHASE146 participantsNational Cancer Institute (NCI)

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NCT06503367Recruiting

Observation Study in Patients Age 0-5 Years With LAMA2-related Congenital Muscular Dystrophy

The goal of this observational study is to understand how young children with LAMA2-related dystrophy move and change over time. We will also learn about how this condition impacts other body systems....

Chicago, IL44 participantsNationwide Children's Hospital

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NCT06430684Recruiting

Feasibility Trial of Sodium-GLucose coTransporter 2 INhibitors in Pediatric Chronic KIDney DiSease

The goal of this study is to learn if a clinical trial of sodium-glucose co-transporter 2 inhibitors (SGLT2i) is possible in youth with chronic kidney disease (CKD). The investigators also plan to exp...

Chicago, ILEARLY_PHASE140 participantsAnn & Robert H Lurie Children's Hospital of Chicago

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NCT04943848Recruiting

rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG

This is a phase I, open label, plus expansion clinical trial evaluating the safety and tolerability of rHSC-DIPGVax in combination with BALSTILIMAB and ZALIFRELIMAB. rHSC-DIPGVax is an off-the-shelf n...

Chicago, ILPHASE136 participantsAnn & Robert H Lurie Children's Hospital of Chicago

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NCT06400186Recruiting

Movement Amplification Gait Training to Enhance Walking Balance Post-Stroke

Stroke is a leading cause of disability in the United States, affecting approximately 795,000 people annually. The Veteran's Health Administration provides over 60,000 outpatient visits for stroke-rel...

Chicago, ILNA30 participantsVA Office of Research and Development

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NCT05711615Recruiting

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

This phase I trial tests the safety, side effects, and best dose of combination therapy with liposomal doxorubicin and peposertib in treating patients with sarcoma that has spread from where it first ...

Chicago, ILPHASE130 participantsNational Cancer Institute (NCI)

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NCT04590690Recruiting

Gut Microbiome and Sex as Risk Factors for Kidney Stones After Bariatric Surgery

This is a single-center study that aims to better understand how diet and sex affect the risk of kidney stones in people who have had gastric bypass surgery. Subjects will be asked to follow a special...

Chicago, ILNA28 participantsUniversity of Chicago

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NCT06291818Recruiting

Self-Adhering Magnetic Device to Treat Corneal Exposure

Paralytic lagophthalmos can be difficult to treat and manage. It has a host of causes and effects, one of which (for the latter) is exposure keratopathy. Untreated, this can lead to corneal ulceration...

Chicago, ILNA25 participantsUniversity of Illinois at Chicago

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NCT05106387Recruiting

An Observational Extension Study for Adult Patients Treated in Study R5459-RT-1944 Who Receive a Kidney Transplant

The main purpose of this study is to continue to see how vonsetamig works in the body and to monitor the outcomes after kidney transplant for participants previously treated in the R5459-RT-1944 study...

Chicago, IL20 participantsRegeneron Pharmaceuticals

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NCT07175051Recruiting

Targeting the Pathophysiology of Sickle Cell-Related Kidney Disease Using the SGLT2 Inhibitors, Empagliflozin

Sickle cell anemia (SCA) is an inherited red blood disorder. The kidneys are among the most commonly affected organ systems in SCA. The Food and Drug Administration (FDA) has approved empagliflozin as...

Chicago, ILPHASE220 participantsUniversity of Illinois at Chicago

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NCT04055818Recruiting

A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease

A randomized control trial in 20 subjects with sickle cell disease comparing oral THU-decitabine to nicotinamide and in combination (THU, decitabine and nicotinamide)....

Chicago, ILPHASE120 participantsEpiDestiny, Inc.

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NCT05913908Recruiting

EFS of the DUO System for Tricuspid Regurgitation

The study is an early feasibility study to measure individual patient clinical outcomes and effectiveness, evaluate the safety and function of the DUO Transcatheter Tricuspid Coaptation Valve System (...

Chicago, ILNA15 participantsCroiValve Limited

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NCT07050186Recruiting

Cemiplimab for the Treatment of Incurable Metastatic or Unresectable NUT Carcinoma

This phase II trial studies how well cemiplimab works in treating patients with nuclear protein of testis (NUT) carcinoma for which no treatment is currently available (incurable) and that has spread ...

Chicago, ILPHASE215 participantsNorthwestern University

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NCT06192576Recruiting

A Real-world Long-term Safety and Immunogenicity Study of Olipudase Alfa Therapy in Pediatric Patients Less Than 2 Years of Age With Acid Sphingomyelinase Deficiency (ASMD)

US, multicenter, cohort, open label observational study with primary data collection. Ancillary protocol-specified procedures to address the study objectives (eg, assessment of ADA) may be considered ...

Chicago, IL10 participantsSanofi

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NCT07230964Recruiting

Correlation Between an Impedance Cardiography Test for Decompensation and the Development of Left Ventricular Replacement Fibrosis

The purpose of this study is to evaluate the effectiveness of impedance cardiography (ICG), the HYPERGRAPH test, in detecting left ventricular decompensation in patients with aortic stenosis, compared...

Chicago, ILNA6 participantsDermed Diagnostics, Inc.

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About Interstitial Cystitis Clinical Trials in Chicago

Interstitial cystitis/bladder pain syndrome is a chronic condition causing bladder pressure, bladder pain, and sometimes pelvic pain. It primarily affects women and can significantly impact quality of life. Treatment includes dietary changes, bladder instillations, oral medications, and neuromodulation.

There are currently 61 interstitial cystitis clinical trials recruiting participants in Chicago, IL. These studies are seeking a combined 14,378 participants. Research is being sponsored by Alexion Pharmaceuticals, Inc., The European Forum for Research and Education in Allergy and Airway Diseases, University of Pennsylvania and 41 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Interstitial Cystitis Clinical Trials in Chicago — FAQ

Are there interstitial cystitis clinical trials in Chicago?

Yes, there are 61 interstitial cystitis clinical trials currently recruiting in Chicago, IL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Chicago?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Chicago research site will contact you about next steps.

Are clinical trials in Chicago free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Chicago studies also compensate for your time and travel.

What interstitial cystitis treatments are being tested?

The 61 active trials in Chicago are testing new therapies including novel drugs, biologics, and treatment approaches for interstitial cystitis.

Data updated August 29, 2026 from ClinicalTrials.gov