Chicago, ILLINOIS5 Active Studies

Lupus Clinical Trials in Chicago, ILLINOIS

Find 5 actively recruiting lupus clinical trials in Chicago, ILLINOIS. Connect with local research sites and explore new treatment options.

5
Active Trials
5
Sponsors
435
Enrolling

Recruiting Lupus Studies in Chicago

RecruitingChicago, ILLINOISNCT06581198

A Study of Rapcabtagene Autoleucel in Systemic Lupus Erythematosus (SLE) Patients With Active, Refractory Lupus Nephritis (LN)

The purpose of this study is to evaluate the efficacy and safety of rapcabtagene autoleucel (administered once following lymphodepletion) versus Standard of Care (SOC) in patients with systemic lupus ...

144 participants
Novartis Pharmaceuticals
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RecruitingChicago, ILLINOISNCT05538208

The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study

The study is a 1-year 2-part double-blinded placebo controlled 2-arm clinical trial. Treatment arms are (1) MMF dosed as per body-surface area (MMFBSA; 600mg/m2 body surface area per dose about every ...

105 participants
Children's Hospital Medical Center, Cincinnati
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RecruitingChicago, ILLINOISNCT05835310

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

A Study to evaluate the PK, PD, efficacy, and safety of Anifrolumab in children with moderate to severe active SLE...

100 participants
AstraZeneca
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RecruitingChicago, ILLINOISNCT05201469

VIBRANT: VIB4920 for Active Lupus Nephritis

This is a multi-center double-blind placebo controlled clinical trial evaluating the efficacy of VIB4920 combined with mycophenolate mofetil (MMF) and prednisone in achieving a renal response in parti...

74 participants
National Institute of Allergy and Infectious Diseases (NIAID)
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RecruitingChicago, ILLINOISNCT06121297

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus...

12 participants
Cabaletta Bio
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About Lupus Clinical Trials in Chicago

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect the joints, skin, kidneys, brain, and other organs. It is more common in women and often involves periods of flares and remission. Treatment includes antimalarials, immunosuppressants, and biologics.

There are currently 5 lupus clinical trials recruiting participants in Chicago, ILLINOIS. These studies are seeking a combined 435 participants. Research is being sponsored by Novartis Pharmaceuticals, Children's Hospital Medical Center, Cincinnati, AstraZeneca and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Lupus Clinical Trials in Chicago — FAQ

Are there lupus clinical trials in Chicago?

Yes, there are 5 lupus clinical trials currently recruiting in Chicago, ILLINOIS. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Chicago?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Chicago research site will contact you about next steps.

Are clinical trials in Chicago free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Chicago studies also compensate for your time and travel.

What lupus treatments are being tested?

The 5 active trials in Chicago are testing new therapies including novel drugs, biologics, and treatment approaches for lupus.

Data updated March 2, 2026 from ClinicalTrials.gov