100 Active Studies

Lupus Clinical Trials Near You

Also searched as: SLE, systemic lupus, lupus erythematosus clinical trials

Find 100 actively recruiting lupus research studies near you. Connect with study sites, check eligibility, and explore new treatment options.

100Active Trials
164+Locations
192,724Participants Needed

Recruiting Studies

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Data: ClinicalTrials.gov · Source of record for eligibility and locations

Top Cities for Lupus Clinical Trials

Lupus clinical trials are recruiting across 164 cities. Here are the cities with the most active studies:

Lupus Trial Phases

NA(37 studies)
PHASE3(15 studies)
PHASE2(15 studies)
PHASE4(7 studies)
PHASE1(6 studies)

68 research organizations are sponsoring lupus trials.

About Lupus

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect the joints, skin, kidneys, brain, and other organs. It is more common in women and often involves periods of flares and remission. Treatment includes antimalarials, immunosuppressants, and biologics.

Clinical trials are advancing new treatments for lupus. Currently, 100 studies are recruiting a combined 192,724 participants across the United States. Research is being conducted by 68 organizations including Scripps Translational Science Institute, Mayo Clinic, Lupus Foundation of America and 65 others.

2026 Lupus Research Landscape

As of July 2026, the lupus clinical trial landscape includes 100 actively recruiting studies across 164 cities in the United States. These studies are collectively seeking 192,724 participants, with an average enrollment target of 1,927 per study.

The research spans multiple phases of development: 37 studies are in NA, 15 studies are in PHASE3, 15 studies are in PHASE2, 7 studies are in PHASE4, 6 studies are in PHASE1. The presence of Phase 3 trials indicates that some lupus treatments are in late-stage testing and may be approaching regulatory review.

Research is being led by 68 different organizations, including Scripps Translational Science Institute, Mayo Clinic, Lupus Foundation of America, Vanda Pharmaceuticals, Children's Hospital of Philadelphia, and 63 others. The large number of sponsors reflects significant research interest and investment in lupus treatment advancement.

Geographically, lupus trials are most concentrated in Miami, Florida (13 trials); Los Angeles, California (10 trials); Philadelphia, Pennsylvania (9 trials); Chicago, Illinois (9 trials); Atlanta, Georgia (8 trials) and 7 other cities.

Featured Lupus Studies

Highlighted recruiting studies for lupus, selected by enrollment size and research scope.

RecruitingNCT05197738

Research Framework Exploring Sleep Health

This is a digital health study in which participants are recruited to collect sleep and activity data from digital activity trackers. We are also collecting survey/questionnaire data on baseline health and sleep characteristics as well as bi-weekly assessments of sleep quality and mood. Overall, we aim to examine how sleep relates to physical and mental health in a large population of activity tra...

Sponsor: Scripps Translational Science Institute· 100,000 participants· 1 location (La Jolla)
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RecruitingNCT00830557

Collecting Medical Information and Tissue Samples From Patients With Pancreatic Cancer or Other Pancreatic Disorders

RATIONALE: Gathering medical information and collecting and storing samples of blood and tissue to test in the laboratory may help doctors develop better ways to screen people at risk for pancreatic cancer or other pancreatic disorders in the future. PURPOSE: This clinical trial is collecting medical information and tissue samples from patients with pancreatic cancer or other pancreatic disorders...

Sponsor: Mayo Clinic· 20,000 participants· 3 locations (Phoenix, Jacksonville, Rochester)
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RecruitingNCT06927219

Research Accelerated by You Lupus Registry

Summary The Lupus Foundation of America (LFA) Research Accelerated by You (RAY) Registry is a fully remote, longitudinal registry designed to collect data from adults and children living with lupus. The primary goal is to better understand the diagnosis, treatment, care, and quality of life for those affected by the disease. Remote Participation This is a decentralized, online-only registry. Part...

Sponsor: Lupus Foundation of America· 10,000 participants· 1 location (Washington D.C.)
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Frequently Asked Questions About Lupus Clinical Trials

Are there lupus clinical trials near me?

Yes, there are 100 lupus clinical trials currently recruiting across 164+ cities in the United States, including Miami, Florida; Los Angeles, California; Philadelphia, Pennsylvania. Browse the studies above to find one at a location convenient for you.

How do I join a lupus clinical trial?

To join a lupus clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.

Are lupus clinical trials free?

Yes, participation in lupus clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.

What types of lupus treatments are being studied?

Current lupus clinical trials are testing a range of approaches across NA (37 studies), PHASE3 (15 studies), PHASE2 (15 studies), PHASE4 (7 studies), PHASE1 (6 studies). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 68 research organizations.

Is it safe to participate in lupus clinical trials?

Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.

Data updated July 19, 2026 from ClinicalTrials.gov

About This Data

Data: ClinicalTrials.gov · Source of record for eligibility and locations

Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.

Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.

Page reviewed by the HelloStudys Research Team · Last updated July 19, 2026 · Data from ClinicalTrials.gov