A Long-term Extension Study of Dazodalibep in Participants With Sjögren's Syndrome (SS)
The primary objective of this study is to evaluate the long-term safety and tolerability of dazodalibep....
A Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults With Active Sjögren's Syndrome
The purpose of this study is to assess the safety and efficacy of two doses of Deucravacitinib in adult participants with Active Sjögren's Syndrome....
Nipocalimab in Moderate to Severe Sjogren's Disease
The purpose of this study is to evaluate the clinical efficacy and safety of nipocalimab in participants with moderate to severe Sjogren's disease (SjD)....
A Study of the Efficacy and Safety of Efgartigimod in Patients With Primary Sjögren's Syndrome
The main purpose of the proposed study is to evaluate the efficacy of efgartigimod PH20 SC in patients with moderate-to-severe Primary Sjögren's Disease (pSjD). The study consists of a double-blinded ...
A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State
Primary Objective: To evaluate the effect of dazodalibep on patient-reported symptoms of SS in participants with moderate-to-severe symptom state Secondary Objectives: 1. To evaluate the effect of ...
A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's Syndrome
The purpose of this study is to measure the efficacy and safety of HZN-1116 in participants with Sjogren's syndrome (SS)....
Efficacy and Safety of IMVT-1402 in Adult Participants With Primary Sjogren's Disease With Moderate to Severe Systemic Disease Activity
This is a Phase 2b, multicenter, randomized, double-blinded, placebo-controlled study to assess the efficacy and safety of IMVT-1402 in adult participants with moderate to severe systemic primary Sjog...
A Study of RSLV-132 in Females With Sjögren's Disease
The goal of this clinical study is to learn if RSLV-132 improves the symptoms of SS in adults. It will also learn about the safety of RSLV-132. The main questions it aims to answer are: * Does RSLV-1...
A Trial to Evaluate the Efficacy and Safety of Sibeprenlimab Administered Subcutaneously in Participants With Sjögren's
This is a phase 2 study to evaluate the effects of sibeprenlimab 400 mg administered subcutaneously (SC) every 4 (Q4) weeks as an add-on to background treatment in participants with Sjögren's disease....
Top Cities for Sjogrens Syndrome Clinical Trials
Sjogrens Syndrome clinical trials are recruiting across 59 cities. Here are the cities with the most active studies:
About Sjogrens Syndrome
Sjogren's syndrome is a chronic autoimmune disorder in which the immune system attacks the glands that produce moisture, causing dry eyes and dry mouth. It can also affect joints, thyroid, kidneys, and other organs. Treatment focuses on relieving symptoms and may include immunosuppressive medications.
Clinical trials are advancing new treatments for sjogrens syndrome. Currently, 9 studies are recruiting a combined 3,843 participants across the United States. Research is being conducted by 7 organizations including Amgen, Bristol-Myers Squibb, Janssen Research & Development, LLC and 4 others.
2026 Sjogrens Syndrome Research Landscape
As of March 2026, the sjogrens syndrome clinical trial landscape includes 9 actively recruiting studies across 59 cities in the United States. These studies are collectively seeking 3,843 participants, with an average enrollment target of 427 per study.
Research is being led by 7 different organizations, including Amgen, Bristol-Myers Squibb, Janssen Research & Development, LLC, argenx, Immunovant Sciences GmbH, and 2 others.
Geographically, sjogrens syndrome trials are most concentrated in Clearwater, Florida (5 trials); Tampa, Florida (4 trials); Boston, Massachusetts (3 trials); Fullerton, California (3 trials); Flagstaff, Arizona (2 trials) and 7 other cities.
Featured Sjogrens Syndrome Studies
Highlighted recruiting studies for sjogrens syndrome, selected by enrollment size and research scope.
A Long-term Extension Study of Dazodalibep in Participants With Sjögren's Syndrome (SS)
The primary objective of this study is to evaluate the long-term safety and tolerability of dazodalibep.
A Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults With Active Sjögren's Syndrome
The purpose of this study is to assess the safety and efficacy of two doses of Deucravacitinib in adult participants with Active Sjögren's Syndrome.
Nipocalimab in Moderate to Severe Sjogren's Disease
The purpose of this study is to evaluate the clinical efficacy and safety of nipocalimab in participants with moderate to severe Sjogren's disease (SjD).
Frequently Asked Questions About Sjogrens Syndrome Clinical Trials
Are there sjogrens syndrome clinical trials near me?
Yes, there are 9 sjogrens syndrome clinical trials currently recruiting across 59+ cities in the United States, including Clearwater, Florida; Tampa, Florida; Boston, Massachusetts. Browse the studies above to find one at a location convenient for you.
How do I join a sjogrens syndrome clinical trial?
To join a sjogrens syndrome clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are sjogrens syndrome clinical trials free?
Yes, participation in sjogrens syndrome clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of sjogrens syndrome treatments are being studied?
Current sjogrens syndrome clinical trials are testing a range of approaches. These include new drugs, combination therapies, medical devices, and other interventions sponsored by 7 research organizations.
Is it safe to participate in sjogrens syndrome clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated March 1, 2026 from ClinicalTrials.gov
About This Data
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated March 1, 2026 · Data from ClinicalTrials.gov