La Jolla, CALIFORNIA12 Active Studies

Lupus Clinical Trials in La Jolla, CALIFORNIA

Find 12 actively recruiting lupus clinical trials in La Jolla, CALIFORNIA. Connect with local research sites and explore new treatment options.

12
Active Trials
11
Sponsors
3,437
Enrolling

Recruiting Lupus Studies in La Jolla

RecruitingLa Jolla, CALIFORNIANCT05620407

A Study to Evaluate Effectiveness and Safety of Deucravacitinib (BMS-986165) Compared With Placebo in Participants With Active Systemic Lupus Erythematosus

The purpose of this study is to evaluate the effectiveness and safety of deucravacitinib compared with placebo in an active moderate to severe Systemic Lupus Erythematosus (SLE) population....

490 participants
Bristol-Myers Squibb
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RecruitingLa Jolla, CALIFORNIANCT05531565

A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

In this study, researchers will learn more about a study drug called litifilimab (BIIB059) in participants with cutaneous lupus erythematosus (CLE). The study will focus on participants who have eithe...

474 participants
Biogen
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RecruitingLa Jolla, CALIFORNIANCT06015737

A 2-stage, Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus

This study aims to evaluate the efficacy and safety of subcutaneous (SC) anifrolumab versus placebo in adult participants with cutaneous lupus erythematosus (CLE)....

460 participants
AstraZeneca
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RecruitingLa Jolla, CALIFORNIANCT06617325

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

The purpose of this study is to evaluate the ability of dapirolizumab pegol (DZP) as an add-on treatment to standard of care (SOC) medication to achieve clinically relevant long term improvement of mo...

450 participants
UCB Biopharma SRL
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RecruitingLa Jolla, CALIFORNIANCT05672576

A Research Study to Evaluate the Efficacy and Safety of Cenerimod in Subjects Suffering From Systemic Lupus Erythematosus

The goal of this clinical trial is to see how well cenerimod reduces symptoms of Systemic Lupus Erythematous in adult patients with moderate to severe symptoms. The main questions it aims to answer ar...

420 participants
Viatris Innovation GmbH
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RecruitingLa Jolla, CALIFORNIANCT05639114

Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 1)

The trial will evaluate efficacy, safety and tolerability of two regimens of ianalumab compared to placebo, given as monthly or quarterly subcutaneous (s.c.) injection on top of standard-of-care (SoC)...

406 participants
Novartis Pharmaceuticals
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RecruitingLa Jolla, CALIFORNIANCT05138133

Phase 3 Study of Anifrolumab in Adult Patients With Active Proliferative Lupus Nephritis

The purpose of this study is to evaluate the efficacy and safety of IV antifrolumab in adult patients with Active Proliferative Lupus Nephritis...

360 participants
AstraZeneca
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RecruitingLa Jolla, CALIFORNIANCT06559163

A Study of Obexelimab in Patients With Systemic Lupus Erythematosus

This study aims to examine the efficacy and safety of obexelimab in participants with systemic lupus erythematosus (SLE)....

190 participants
Zenas BioPharma (USA), LLC
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RecruitingLa Jolla, CALIFORNIANCT05201469

VIBRANT: VIB4920 for Active Lupus Nephritis

This is a multi-center double-blind placebo controlled clinical trial evaluating the efficacy of VIB4920 combined with mycophenolate mofetil (MMF) and prednisone in achieving a renal response in parti...

74 participants
National Institute of Allergy and Infectious Diseases (NIAID)
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RecruitingLa Jolla, CALIFORNIANCT06776432

Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep Apnea

The primary purpose of this study is to evaluate the effectiveness of sivopixant, acetazolamide and SASS-001 in adults with sleep apnea with a central component....

60 participants
Shionogi Apnimed Sleep Science
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RecruitingLa Jolla, CALIFORNIANCT05629208

Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)

The goal of this clinical study is to test how edecesertib (formerly known as GS-5718) can be useful in treating Cutaneous Lupus Erythematosus (CLE) in participants with CLE. Information on what is ha...

33 participants
Gilead Sciences
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RecruitingLa Jolla, CALIFORNIANCT06064929

A Study to Learn More About the Safety and Effects of Felzartamab in Adults With Lupus Nephritis Aged 18 to 75 Years Old

In this study, researchers will learn more about the use of felzartamab in people with active lupus nephritis, also known as LN. In people with LN, antibodies build up in the glomeruli of the kidneys....

20 participants
HI-Bio, A Biogen Company
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About Lupus Clinical Trials in La Jolla

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect the joints, skin, kidneys, brain, and other organs. It is more common in women and often involves periods of flares and remission. Treatment includes antimalarials, immunosuppressants, and biologics.

There are currently 12 lupus clinical trials recruiting participants in La Jolla, CALIFORNIA. These studies are seeking a combined 3,437 participants. Research is being sponsored by Bristol-Myers Squibb, Biogen, AstraZeneca and 8 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Lupus Clinical Trials in La Jolla — FAQ

Are there lupus clinical trials in La Jolla?

Yes, there are 12 lupus clinical trials currently recruiting in La Jolla, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in La Jolla?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the La Jolla research site will contact you about next steps.

Are clinical trials in La Jolla free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many La Jolla studies also compensate for your time and travel.

What lupus treatments are being tested?

The 12 active trials in La Jolla are testing new therapies including novel drugs, biologics, and treatment approaches for lupus.

Data updated March 2, 2026 from ClinicalTrials.gov