Chicago, ILLINOIS5 Active Studies

Systemic Lupus Erythematosus Clinical Trials in Chicago, ILLINOIS

Find 5 actively recruiting systemic lupus erythematosus clinical trials in Chicago, ILLINOIS. Connect with local research sites and explore new treatment options.

5
Active Trials
5
Sponsors
435
Enrolling

Recruiting Systemic Lupus Erythematosus Studies in Chicago

RecruitingChicago, ILLINOISNCT06581198

A Study of Rapcabtagene Autoleucel in Systemic Lupus Erythematosus (SLE) Patients With Active, Refractory Lupus Nephritis (LN)

The purpose of this study is to evaluate the efficacy and safety of rapcabtagene autoleucel (administered once following lymphodepletion) versus Standard of Care (SOC) in patients with systemic lupus ...

144 participants
Novartis Pharmaceuticals
View Study Details
RecruitingChicago, ILLINOISNCT05538208

The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study

The study is a 1-year 2-part double-blinded placebo controlled 2-arm clinical trial. Treatment arms are (1) MMF dosed as per body-surface area (MMFBSA; 600mg/m2 body surface area per dose about every ...

105 participants
Children's Hospital Medical Center, Cincinnati
View Study Details
RecruitingChicago, ILLINOISNCT05835310

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

A Study to evaluate the PK, PD, efficacy, and safety of Anifrolumab in children with moderate to severe active SLE...

100 participants
AstraZeneca
View Study Details
RecruitingChicago, ILLINOISNCT05201469

VIBRANT: VIB4920 for Active Lupus Nephritis

This is a multi-center double-blind placebo controlled clinical trial evaluating the efficacy of VIB4920 combined with mycophenolate mofetil (MMF) and prednisone in achieving a renal response in parti...

74 participants
National Institute of Allergy and Infectious Diseases (NIAID)
View Study Details
RecruitingChicago, ILLINOISNCT06121297

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus...

12 participants
Cabaletta Bio
View Study Details

About Systemic Lupus Erythematosus Clinical Trials in Chicago

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect the joints, skin, kidneys, blood cells, brain, heart, and lungs. It is characterized by periods of flares and remission. Treatment includes antimalarials, immunosuppressants, corticosteroids, and biologics like belimumab.

There are currently 5 systemic lupus erythematosus clinical trials recruiting participants in Chicago, ILLINOIS. These studies are seeking a combined 435 participants. Research is being sponsored by Novartis Pharmaceuticals, Children's Hospital Medical Center, Cincinnati, AstraZeneca and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Systemic Lupus Erythematosus Clinical Trials in Chicago — FAQ

Are there systemic lupus erythematosus clinical trials in Chicago?

Yes, there are 5 systemic lupus erythematosus clinical trials currently recruiting in Chicago, ILLINOIS. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Chicago?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Chicago research site will contact you about next steps.

Are clinical trials in Chicago free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Chicago studies also compensate for your time and travel.

What systemic lupus erythematosus treatments are being tested?

The 5 active trials in Chicago are testing new therapies including novel drugs, biologics, and treatment approaches for systemic lupus erythematosus.

Data updated March 2, 2026 from ClinicalTrials.gov