Cleveland, OH5 Active Studies

Brain Cancer Clinical Trials in Cleveland, OH

Find 5 actively recruiting brain cancer clinical trials in Cleveland, OH. Connect with local research sites and explore new treatment options.

5
Active Trials
5
Sponsors
702
Enrolling

Recruiting Brain Cancer Studies in Cleveland

RecruitingCleveland, OHNCT02977780

INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)

This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM). The drugs involved in this study are : * Abemaciclib * Temozolomide (temodar) * Neratini...

460 participants
Patrick Wen, MD
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RecruitingCleveland, OHNCT05303519

Safusidenib Phase 2 Study in IDH1 Mutant Glioma

This is a 2-part study. The purpose of Part 1 of the study is to evaluate the efficacy, safety, and pharmacokinetic (PK) characteristics of safusidenib in participants with recurrent/progressive IDH1-...

125 participants
Nuvation Bio Inc.
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RecruitingCleveland, OHNCT02704858

Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma

This multi-site, Phase 1/2a clinical trial is an open-label study to identify the safety, pharmacokinetics, and efficacy of a repeated dose regimen of NEO100 (perillyl alcohol) for the treatment of pa...

49 participants
Neonc Technologies, Inc.
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RecruitingCleveland, OHNCT01891318

Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study

This Phase I/II trial studies the ability to stop brain metastases from coming back after treatment with radiosurgery followed by surgical resection. It will also evaluate the side effects of these co...

36 participants
Case Comprehensive Cancer Center
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RecruitingCleveland, OHNCT04559230

Sacituzumab Govitecan in Recurrent Glioblastoma

This is an open-label single arm study. All patients will receive the study drug. The aim of the study is to compare overall survival (OS) of patients with recurrent brain tumor, known as Glioblastoma...

32 participants
The University of Texas Health Science Center at San Antonio
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About Brain Cancer Clinical Trials in Cleveland

Brain cancer includes tumors that originate in the brain (primary) or spread from other areas (metastatic). Glioblastoma (GBM) is the most common and aggressive primary brain tumor. Treatment typically combines surgery, radiation, and chemotherapy, with immunotherapy trials underway.

There are currently 5 brain cancer clinical trials recruiting participants in Cleveland, OH. These studies are seeking a combined 702 participants. Research is being sponsored by Patrick Wen, MD, Nuvation Bio Inc., Neonc Technologies, Inc. and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Brain Cancer Clinical Trials in Cleveland — FAQ

Are there brain cancer clinical trials in Cleveland?

Yes, there are 5 brain cancer clinical trials currently recruiting in Cleveland, OH. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Cleveland?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Cleveland research site will contact you about next steps.

Are clinical trials in Cleveland free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Cleveland studies also compensate for your time and travel.

What brain cancer treatments are being tested?

The 5 active trials in Cleveland are testing new therapies including novel drugs, biologics, and treatment approaches for brain cancer.

Data updated March 2, 2026 from ClinicalTrials.gov