6 Cardiomyopathy Clinical Trials in Cleveland, OH (2026)

Q: How do I join a clinical trial in Cleveland?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Cleveland research site will contact you.

Recruiting Cardiomyopathy Studies in Cleveland

NCT04080492Recruiting

A Cardiac Disease Quality of Life Study

A prospective, longitudinal, non-comparator, non-randomized observational cohort study to assess the quality of life in adult patients affected by hypertrophic cardiomyopathy and thoracic aortic dilat...

Cleveland, OH1,200 participantsThe Cleveland Clinic

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NCT05965258Recruiting

Phenotypic Classification of FMR With CMR

The goal of the current research is to develop personalized risk prediction for functional mitral regurgitation (FMR) patients through explainable unsupervised phenomapping enriched with advanced card...

Cleveland, OH360 participantsThe Cleveland Clinic

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NCT07054073Recruiting

HCMR Re-Imaging Study

This study aims to learn what might predict heart problems (like sudden death from a fast heart rhythm or heart failure) in people with a genetic condition called hypertrophic cardiomyopathy (HCM). HC...

Cleveland, OH314 participantsChristopher Kramer

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NCT06311708Recruiting

Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)

This is a multicenter, non-interventional study to observe the natural progression of the disease and to study the prevalence of pre-existing antibodies to AAV9 used for gene therapy in a population o...

Cleveland, OH200 participantsTenaya Therapeutics

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NCT05836259Recruiting

Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM

This is a first-in-human, non-randomized, open-label study designed to evaluate the safety, tolerability, and pharmacodynamics (PD) of TN-201 in adult patients with symptomatic hypertrophic cardiomyop...

Cleveland, OH30 participantsTenaya Therapeutics

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NCT06228924Recruiting

Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC

This first-in-human study is designed to evaluate the safety, and preliminary efficacy (PD) of TN-401 gene therapy in adult patients with symptomatic PKP2 mutation-associated ARVC....

Cleveland, OH15 participantsTenaya Therapeutics

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About Cardiomyopathy Clinical Trials in Cleveland

Cardiomyopathy refers to diseases of the heart muscle that make it harder for the heart to pump blood. Types include dilated, hypertrophic, and restrictive cardiomyopathy. Treatment depends on the type and may include medications, devices, or heart transplant.

There are currently 6 cardiomyopathy clinical trials recruiting participants in Cleveland, OH. These studies are seeking a combined 2,119 participants. Research is being sponsored by The Cleveland Clinic, Christopher Kramer, Tenaya Therapeutics. Clinical trial participation is free and participants receive study-related medical care at no cost.

Cardiomyopathy Clinical Trials in Cleveland — FAQ

Are there cardiomyopathy clinical trials in Cleveland?

Yes, there are 6 cardiomyopathy clinical trials currently recruiting in Cleveland, OH. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Cleveland?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Cleveland research site will contact you about next steps.

Are clinical trials in Cleveland free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Cleveland studies also compensate for your time and travel.

What cardiomyopathy treatments are being tested?

The 6 active trials in Cleveland are testing new therapies including novel drugs, biologics, and treatment approaches for cardiomyopathy.

Data updated July 13, 2026 from ClinicalTrials.gov