21 Osteogenesis Imperfecta Clinical Trials in Cleveland, OH (2026)

Q: How do I join a clinical trial in Cleveland?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Cleveland research site will contact you.

Recruiting Osteogenesis Imperfecta Studies in Cleveland

NCT05489549Recruiting

Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

Approximately 1.5 million of the 44 million Blacks in the United States are carriers of the valine-to-isoleucine substitution at position 122 (V122I) in the transthyretin (TTR) protein. Virtually excl...

Cleveland, OH500 participantsUniversity of Texas Southwestern Medical Center

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NCT04260022Recruiting

Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL

A multi-center, open-label, randomized, phase Ib study to evaluate the pharmacokinetics (PK) of HQP1351 and to determine the recommended phase 2 dose (RP2D) of HQP1351 in subjects with CML chronic pha...

Cleveland, OHPHASE1242 participantsAscentage Pharma Group Inc.

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NCT07214311Recruiting

Evaluation of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Knee Arthroplasty

The goal of this clinical trial is to evaluate whether the investigational drug PLG0206 can help reduce recurrence of infection in adults who have undergone total knee replacement and are receiving a ...

Cleveland, OHPHASE2240 participantsPeptilogics

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NCT06263088Recruiting

EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.

This research study is being conducted to improve the quality of care of participants who have a diagnosis of gastrointestinal cancer (anal, colon, rectal, esophageal, stomach, small bowel, appendix, ...

Cleveland, OHNA200 participantsCase Comprehensive Cancer Center

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NCT04379115Recruiting

Optimization of NIBS for Treatment of Addiction

The purpose of this study is to assess the effects of transcranial Direct Current Stimulation (tDCS) applied in conjunction with Transcranial Ultrasound (TUS) for the treatment of addiction in opiate ...

Cleveland, OHNA126 participantsCase Western Reserve University

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NCT07073963Recruiting

Virtual Patient Groups for Sarcoidosis Associated Fatigue

This research study is testing whether Mindfulness-Based Stress Reduction (MBSR) can help reduce fatigue in people with sarcoidosis. The study will also look at whether MBSR can improve symptoms of an...

Cleveland, OHNA100 participantsThe Cleveland Clinic

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NCT06680037Recruiting

A Study to Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune Disorders

The main objective of the study is to determine the recommended phase 2 dose (RP2D) of Azercabtagene zapreleucel (azer-cel)....

Cleveland, OHPHASE1100 participantsTG Therapeutics, Inc.

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NCT06205121Recruiting

Efficacy and Safety Study of OATD-01 in Patients With Active Pulmonary Sarcoidosis

This is a Phase 2, randomized, double-blind, placebo-controlled, adaptive, multicenter study to evaluate the efficacy, safety, tolerability, Pharmacodynamics (PD), and Pharmacokinetics (PK) of OATD-01...

Cleveland, OHPHASE296 participantsMolecure S.A.

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NCT05957367Recruiting

A Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced Malignancies

This is a Phase 1/2, multicenter, open-label (unless otherwise specified in a combination-specific module) study of inlexisertib in combination with anticancer therapies. Modules within the master pro...

Cleveland, OHPHASE194 participantsDeciphera Pharmaceuticals, LLC

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NCT07081646Recruiting

A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.

Open-label Phase 1b/2 study with primary objective of this study is to evaluate the safety, tolerability and efficacy of AZD0120 in participants with light chain (AL) amyloidosis....

Cleveland, OHPHASE191 participantsAlexion Pharmaceuticals, Inc.

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NCT07812649Recruiting

NIRAF-camera Versus Conventional Surgery in Preoperative Imaging Negative Primary Hyperparathyroidism

Primary hyperparathyroidism (PHPT) is a prevalent endocrine disorder, with an estimated prevalence of 0.86% in the United States. The only definitive treatment for PHPT is parathyroidectomy. Preoperat...

Cleveland, OHNA80 participantsThe Cleveland Clinic

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NCT05484635Recruiting

Mesh Removal Versus No Mesh Removal for Chronic Groin Pain After Inguinal Hernia Repair

This study is evaluating the management of chronic post-operative inguinal hernia pain and the impact of hernia mesh removal after previous minimally invasive inguinal hernia repairs. The study aims ...

Cleveland, OHNA70 participantsDavid Krpata

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NCT06805825Recruiting

A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit

This open-label clinical trial will evaluate the safety and tolerability of NN3201 in subjects with advanced and/or metastatic solid tumors known to express c-Kit....

Cleveland, OHPHASE167 participantsNovelty Nobility, Inc.

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NCT06569147Recruiting

Elranatamab in Patients With Relapsed or Refractory AL Amyloidosis

This study will evaluate the safety, tolerability and efficacy of elranatamab in patients with relapsed or refractory AL amyloidosis....

Cleveland, OHPHASE149 participantsBrigham and Women's Hospital

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NCT05834244Recruiting

A Phase Ib Trial of Azacitidine, Venetoclax and Allogeneic NK Cells for Acute Myeloid Leukemia (ADVENT-AML)

To learn if adding a healthy person's natural killer (NK) cells to the combination of Azacitidine and Venetoclax can help to control AML. NK cells are cancer- and infection-fighting immune cells....

Cleveland, OHPHASE132 participantsM.D. Anderson Cancer Center

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NCT06643884Recruiting

Suprachoroidal Administration in Subjects With Choroidal Metastasis From Breast or Lung Primary Tumors

The primary objective is to assess the safety and tolerability of bel-sar treatment in subjects with choroidal metastasis from breast or lung primary tumors....

Cleveland, OHPHASE224 participantsAura Biosciences

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NCT06129734Recruiting

Decitabine and Venetoclax Treatment as Maintenance Therapy in Patients Post Allograft Stem Cell Transplant

The goal of this interventional clinical trial is to determine if low doses of gentle chemotherapy after bone marrow transplant may prevent relapse and promote an increase in survival and decrease in ...

Cleveland, OHPHASE120 participantsBenjamin Tomlinson

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NCT04332341Recruiting

Study of Nicotinamide Riboside Supplementation in Allogeneic Hematopoietic Cell Transplantation

The purpose of this study is to find a safe and tolerable way to improve engraftment after transplant. Research studies have shown that adding nicotinamide riboside to donor cells has the potential to...

Cleveland, OHEARLY_PHASE120 participantsCase Comprehensive Cancer Center

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NCT03378102Recruiting

Antigen Specific Adoptive T Cell Therapy for Adenovirus Infection After Hematopoietic Stem Cell Transplantation

The purpose of this study is to determine if it is possible to treat an infection with a cell-based immunotherapy (therapy that uses the patient's own immune system to treat the infection). This treat...

Cleveland, OHEARLY_PHASE120 participantsMari Dallas

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NCT06543381Recruiting

Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML After Donor Hematopoietic Cell Transplant

This phase I trial tests the safety, side effects, and effectiveness of olutasidenib in preventing the return of disease (relapse) in patients who have undergone donor (allogeneic) hematopoietic cell ...

Cleveland, OHPHASE115 participantsCity of Hope Medical Center

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NCT07024316Recruiting

A Study to Investigate the Improvement of Photosensitivity in Terms of Skin Lesions Associated With CEP Following Administration of Oral ATL-001 (Ciclopirox Oral Solution) in Participants Aged >18 Years of Age With CEP

This is a study to investigate the effect of oral ATL-001 (ciclopirox) in CEP (Congenital Erythropoietic Porphyria) patients. During the study, it will be measured the improvement of skin lesions, fat...

Cleveland, OHPHASE16 participantsAtlas Molecular Pharma

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About Osteogenesis Imperfecta Clinical Trials in Cleveland

Osteogenesis imperfecta is a group of genetic disorders mainly affecting the bones, causing them to break easily, often from little or no apparent cause. It is caused by defects in collagen production. Treatment includes bisphosphonates, physical therapy, and surgical rodding.

There are currently 21 osteogenesis imperfecta clinical trials recruiting participants in Cleveland, OH. These studies are seeking a combined 2,192 participants. Research is being sponsored by University of Texas Southwestern Medical Center, Ascentage Pharma Group Inc., Peptilogics and 16 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Osteogenesis Imperfecta Clinical Trials in Cleveland — FAQ

Are there osteogenesis imperfecta clinical trials in Cleveland?

Yes, there are 21 osteogenesis imperfecta clinical trials currently recruiting in Cleveland, OH. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Cleveland?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Cleveland research site will contact you about next steps.

Are clinical trials in Cleveland free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Cleveland studies also compensate for your time and travel.

What osteogenesis imperfecta treatments are being tested?

The 21 active trials in Cleveland are testing new therapies including novel drugs, biologics, and treatment approaches for osteogenesis imperfecta.

Data updated October 17, 2026 from ClinicalTrials.gov