4 Sickle Cell Disease Clinical Trials in Columbus, OH (2026)

Q: How do I join a clinical trial in Columbus?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Columbus research site will contact you.

Recruiting Sickle Cell Disease Studies in Columbus

NCT06919224Recruiting

Delivering Patient-Facing Evidence-Based Guidelines Through mHealth to Adults With Sickle Cell Disease

In a hybrid type I effectiveness-implementation trial, our three-center research teams aim to examine whether empowering adults with sickle cell disease (SCD) with patient-facing SCD-specific guidelin...

Columbus, OHNA287 participantsOhio State University

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NCT03587272Recruiting

Minimizing Toxicity in HLA-identical Sibling Donor Transplantation for Children With Sickle Cell Disease

This multisite prospective study seeks to determine if HLA-identical sibling donor transplantation using alemtuzumab, low dose total-body irradiation, and sirolimus (Sickle transplant Using a Nonmyelo...

Columbus, OHPHASE2100 participantsRobert Nickel

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NCT07224360Recruiting

Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)

This is a phase 2a, global, multicenter, randomized, double-blind, placebo-controlled study investigating the safety of anumigilimab administered subcutaneously (SC) at the maximum tolerated dose (MTD...

Columbus, OHPHASE263 participantsCSL Behring

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NCT04819841Recruiting

Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease

This study is a first-in-human, single-arm, open-label Phase I/II study of nula-cel in approximately 15 participants, diagnosed with severe Sickle Cell Disease. The primary objective is to evaluate sa...

Columbus, OHPHASE115 participantsKamau Therapeutics

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About Sickle Cell Disease Clinical Trials in Columbus

Sickle cell disease is a group of inherited blood disorders where abnormal hemoglobin causes red blood cells to become rigid and sickle-shaped. It causes pain crises, organ damage, and shortened life expectancy. Treatment includes hydroxyurea, blood transfusions, and gene therapy.

There are currently 4 sickle cell disease clinical trials recruiting participants in Columbus, OH. These studies are seeking a combined 465 participants. Research is being sponsored by Ohio State University, Robert Nickel, CSL Behring and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Sickle Cell Disease Clinical Trials in Columbus — FAQ

Are there sickle cell disease clinical trials in Columbus?

Yes, there are 4 sickle cell disease clinical trials currently recruiting in Columbus, OH. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Columbus?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Columbus research site will contact you about next steps.

Are clinical trials in Columbus free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Columbus studies also compensate for your time and travel.

What sickle cell disease treatments are being tested?

The 4 active trials in Columbus are testing new therapies including novel drugs, biologics, and treatment approaches for sickle cell disease.

Data updated October 16, 2026 from ClinicalTrials.gov