Columbus, OHIO6 Active Studies

Spinal Muscular Atrophy Clinical Trials in Columbus, OHIO

Find 6 actively recruiting spinal muscular atrophy clinical trials in Columbus, OHIO. Connect with local research sites and explore new treatment options.

6
Active Trials
6
Sponsors
804
Enrolling

Recruiting Spinal Muscular Atrophy Studies in Columbus

RecruitingColumbus, OHIONCT05668988

A Study of DZD9008 Versus Platinum-Based Doublet Chemotherapy in Local Advanced or Metastatic Non-small Cell Lung Cancer (WU-KONG28)

This is a phase 3, open-label, randomized, multi-center study assessing the efficacy and safety of DZD9008 versus platinum-based doublet chemotherapy in participants with locally advanced or metastati...

320 participants
Dizal Pharmaceuticals
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RecruitingColumbus, OHIONCT04317534

Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm

A randomized trial of adjuvant Pembrolizumab following surgical resection versus observation following surgical resection in patients with stage I non-small cell lung cancer (NSCLC) with primary tumor...

244 participants
Greg Durm, MD
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RecruitingColumbus, OHIONCT04367311

Adjuvant Treatment With Cisplatin-based Chemotherapy Plus Concomitant Atezolizumab in Patients With Stage I (Tumors ≥ 4cm), IIA, IIB, and Select Stage III [Any T1-3 N1-2 and T4N0-2] Resected Non-small Cell Lung Cancer (NSCLC) and the Clearance of Circulating Tumor DNA (ctDNA)

The vast majority of patients with stage I (tumors ≥ 4cm), IIA, IIB (and select stage III) NSCLC are managed with upfront surgery, followed by adjuvant chemotherapy. However, relapse rates remain high...

100 participants
Nasser Hanna
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RecruitingColumbus, OHIONCT04919382

Temozolomide and Atezolizumab as Second or Third Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer

This phase II trial studies the effects of temozolomide and atezolizumab as second or third line treatment for patients with small cell lung cancer that has spread to other places in the body (metasta...

56 participants
Dwight Owen
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RecruitingColumbus, OHIONCT05794139

Safety and Efficacy of NMD670 in Ambulatory Adult Patients With Type 3 Spinal Muscular Atrophy

The purpose of this study is to evaluate the efficacy, safety, tolerability and pharmacokinetics of NMD670 in the treatment of ambulatory adults with spinal muscular atrophy type 3...

54 participants
NMD Pharma A/S
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RecruitingColumbus, OHIONCT04699838

Chemo-Immunotherapy Followed by Durvalumab and Ceralasertib in Treatment Naïve Patients With Extensive Stage Small Cell Lung Cancer

The primary objective of this single arm study is to estimate the progression free survival of previously-untreated patients with extensive stage small cell lung cancer. Patients will receive initial ...

30 participants
Muhammad Furqan
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About Spinal Muscular Atrophy Clinical Trials in Columbus

Spinal muscular atrophy (SMA) is a genetic neuromuscular disorder that causes loss of motor neurons, leading to progressive muscle weakness and atrophy. It is the leading genetic cause of infant death. Revolutionary gene therapies and SMN-enhancing drugs have transformed treatment.

There are currently 6 spinal muscular atrophy clinical trials recruiting participants in Columbus, OHIO. These studies are seeking a combined 804 participants. Research is being sponsored by Dizal Pharmaceuticals, Greg Durm, MD, Nasser Hanna and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Spinal Muscular Atrophy Clinical Trials in Columbus — FAQ

Are there spinal muscular atrophy clinical trials in Columbus?

Yes, there are 6 spinal muscular atrophy clinical trials currently recruiting in Columbus, OHIO. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Columbus?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Columbus research site will contact you about next steps.

Are clinical trials in Columbus free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Columbus studies also compensate for your time and travel.

What spinal muscular atrophy treatments are being tested?

The 6 active trials in Columbus are testing new therapies including novel drugs, biologics, and treatment approaches for spinal muscular atrophy.

Data updated March 2, 2026 from ClinicalTrials.gov