10 Cystic Fibrosis Clinical Trials in Denver, CO (2026)

Q: How do I join a clinical trial in Denver?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Denver research site will contact you.

Recruiting Cystic Fibrosis Studies in Denver

NCT06504589Recruiting

A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

The REACH study is for people with CF who do not take cystic fibrosis transmembrane conductance regulator (CFTR) modulators. The goal of the REACH study is to collect research data, including health d...

Denver, CO400 participantsNicole Hamblett

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NCT06559150Recruiting

A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis

This study is a randomized, double-blind, placebo-controlled study designed to assess the efficacy and safety of ensifentrine inhalation suspension (3 mg) delivered twice daily via standard jet nebuli...

Denver, COPHASE2284 participantsVerona Pharma plc

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NCT06683092Recruiting

Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)

RETRIAL is a multi-site observational study of people with Cystic Fibrosis (PWCF) ages 6 and up starting the new triple-therapy modulator (vanzacaftor/tezacaftor/deutivacaftor (VTD)), after having exp...

Denver, CO200 participantsBoston Children's Hospital

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NCT06237335Recruiting

A Phase 2 Study Evaluating Safety and Tolerability of RCT2100 (CFTR mRNA) in Healthy Participants and in Participants With CF

This is the first-in-human study with RCT2100 and is designed to provide safety and tolerability data for future clinical studies....

Denver, COPHASE2192 participantsReCode Therapeutics

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NCT06950892Recruiting

Remote Sputum Collection in Cystic Fibrosis

Elexacaftor/Tezacaftor/Ivacaftor or Trikafta improves lung health in people with cystic fibrosis (CF), including decreased cough and mucous production. Diagnosing lung infections has become more chall...

Denver, CO150 participantsUniversity of Pennsylvania

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NCT06296394Recruiting

Health Outcomes of Parents With Cystic Fibrosis-Aim 2

The goal of this observational prospective study is to determine the health impact of parenthood on United States (US) people with CF in the era of CF transmembrane regulator protein (CFTR) modulators...

Denver, CO146 participantsUniversity of Pittsburgh

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NCT07071324Recruiting

CF Wellness Program

This study is a pilot randomized control trial (RCT; N=80) comparing the Cystic Fibrosis Wellness Program (CFWP) to usual care (UC) to evaluate (1) Intervention Adherence (completion of the CFWP Coach...

Denver, CONA80 participantsJohns Hopkins University

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NCT06429176Recruiting

Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients with Cystic Fibrosis

The goal of this clinical trial is to learn if drug SPL84 is safe for adult patients with cystic fibrosis (CF). It will also learn if the drug works to treat works to treat CF with a specific mutation...

Denver, COPHASE264 participantsSpliSense Ltd.

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NCT06998043Recruiting

Study With Phage for CF Subjects With Pseudomonas Lung Infection

The goal of this Phase 2b clinical trial is to see if nebulized phage (BX004) can treat chronic Pseudomonas aeruginosa (PsA) lung infection in CF subjects. The primary goal is to see if 8 weeks of twi...

Denver, COPHASE263 participantsBiomX Ltd

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NCT05248230Recruiting

4D-710 in Adult Patients With Cystic Fibrosis

This is a Phase 1/2 multicenter, open-label, single dose trial of 4D-710 investigational gene therapy in adults with cystic fibrosis....

Denver, COPHASE230 participants4D Molecular Therapeutics

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About Cystic Fibrosis Clinical Trials in Denver

Cystic fibrosis is a genetic disorder that causes thick, sticky mucus to build up in the lungs, digestive tract, and other organs. It is caused by mutations in the CFTR gene. CFTR modulator therapies have dramatically improved outcomes, along with airway clearance techniques and nutritional support.

There are currently 10 cystic fibrosis clinical trials recruiting participants in Denver, CO. These studies are seeking a combined 1,609 participants. Research is being sponsored by Nicole Hamblett, Verona Pharma plc, Boston Children's Hospital and 7 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Cystic Fibrosis Clinical Trials in Denver — FAQ

Are there cystic fibrosis clinical trials in Denver?

Yes, there are 10 cystic fibrosis clinical trials currently recruiting in Denver, CO. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Denver?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Denver research site will contact you about next steps.

Are clinical trials in Denver free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Denver studies also compensate for your time and travel.

What cystic fibrosis treatments are being tested?

The 10 active trials in Denver are testing new therapies including novel drugs, biologics, and treatment approaches for cystic fibrosis.

Data updated July 17, 2026 from ClinicalTrials.gov