Denver, COLORADO5 Active Studies

Depression Clinical Trials in Denver, COLORADO

Find 5 actively recruiting depression clinical trials in Denver, COLORADO. Connect with local research sites and explore new treatment options.

5
Active Trials
5
Sponsors
906
Enrolling

Recruiting Depression Studies in Denver

RecruitingDenver, COLORADONCT06308653

Psilocybin for Major Depressive Disorder (MDD)

Approximately 240 eligible adult participants (≥18 years old) who meet Diagnostic and Statistical Manual of Mental Disorders (DSM-5-TR) criteria for Major Depressive Disorder (MDD) will be enrolled. P...

240 participants
Usona Institute
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RecruitingDenver, COLORADONCT06564818

"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"

The purpose of this study is to examine the efficacy, safety, and tolerability of CYB003 compared to matching placebo as adjunctive treatment in participants with MDD....

220 participants
Cybin IRL Limited
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RecruitingDenver, COLORADONCT06547489

GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder

The goal of this clinical trial is to learn if GATE-251 works to treat depression in adults. It will also learn about the safety of GATE-251. The main questions it aims to answer are: Does GATE-251 r...

164 participants
Syndeio Biosciences, Inc
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RecruitingDenver, COLORADONCT06524830

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

This Phase 2 study (protocol number VLS-01-203) will determine the efficacy, safety, and tolerability of short-term treatment with a VLS-01 transmucosal buccal film (VLS-01-BU) in patients with treatm...

142 participants
atai Therapeutics, Inc.
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RecruitingDenver, COLORADONCT06941844

A Phase 3 Trial of MM120 for Major Depressive Disorder (Emerge)

A Phase 3 Double-blind, Placebo-controlled Study (Part A) with an Open-label Extension (Part B) Evaluating MM120 Compared to Placebo in Major Depressive Disorder - Emerge...

140 participants
Mind Medicine, Inc.
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About Depression Clinical Trials in Denver

Depression (major depressive disorder) is a common and serious mood disorder that negatively affects how you feel, think, and handle daily activities. It affects over 280 million people globally. Treatment includes psychotherapy, antidepressant medications, and brain stimulation therapies.

There are currently 5 depression clinical trials recruiting participants in Denver, COLORADO. These studies are seeking a combined 906 participants. Research is being sponsored by Usona Institute, Cybin IRL Limited, Syndeio Biosciences, Inc and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Depression Clinical Trials in Denver — FAQ

Are there depression clinical trials in Denver?

Yes, there are 5 depression clinical trials currently recruiting in Denver, COLORADO. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Denver?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Denver research site will contact you about next steps.

Are clinical trials in Denver free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Denver studies also compensate for your time and travel.

What depression treatments are being tested?

The 5 active trials in Denver are testing new therapies including novel drugs, biologics, and treatment approaches for depression.

Data updated March 2, 2026 from ClinicalTrials.gov