17 Colorectal Cancer Clinical Trials in Duarte, CA (2026)

Q: How do I join a clinical trial in Duarte?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Duarte research site will contact you.

Recruiting Colorectal Cancer Studies in Duarte

NCT07224789Recruiting

Liquid Biopsy for Early Detection of Colorectal Cancer Using Circular RNA

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. This study aims to develop a non-invasive liquid biopsy assay using plasma-derived cell-free circular RNAs (cf-circRNAs) ...

Duarte, CA600 participantsCity of Hope Medical Center

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NCT07228832Recruiting

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

A Randomized, Active-Controlled, Double-blind, Multicenter, Phase 3 Clinical Study of Ivonescimab in Combination with mFOLFOX6 (Oxaliplatin, Leucovorin and 5-Fluorouracil) versus Bevacizumab in Combin...

Duarte, CAPHASE3600 participantsSummit Therapeutics

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NCT07224815Recruiting

cfDNA 5mC/5hmC Biomarkers to Predict Chemotherapy Response in Metastatic Colorectal Cancer

The EpiCORE study aims to identify cfDNA-based epigenetic markers predictive of response to first-line chemotherapy (FOLFOX or FOLFIRI) in metastatic colorectal cancer (mCRC). By integrating 5-methyl...

Duarte, CA600 participantsCity of Hope Medical Center

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NCT04929223Recruiting

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

This open-label, exploratory study is designed to evaluate the safety and efficacy of targeted therapies or immunotherapy as single agents or combinations, in participants with metastatic colorectal c...

Duarte, CAPHASE1542 participantsHoffmann-La Roche

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NCT07224724Recruiting

Exosome-derived Extrahepatic Metastasis Detection By Liquid Biopsy In Colorectal Cancer Liver Metastases

Colorectal cancer is the third most common malignancy worldwide, and prognosis largely depends on how effectively metastatic disease is managed. The liver is the most frequent and prognostically impor...

Duarte, CA500 participantsCity of Hope Medical Center

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NCT07224841Recruiting

Development of a cfDNA 5mC/5hmC-based Biomarker Panel to Predict Targeted Therapy Efficacy in mCRC

The EpiDRIVE study aims to identify cfDNA-based epigenetic determinants of response in metastatic colorectal cancer (mCRC) patients treated with EGFR- or VEGF-targeted therapy. By integrating 5-methy...

Duarte, CA500 participantsCity of Hope Medical Center

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NCT06342401Recruiting

Early Onset Colorectal Cancer Detection

Colorectal cancer (CRC) once predominantly affected older individuals, but in recent years has witnessed a progressive increase in incidence among young adults. Once rare, early-onset colorectal cance...

Duarte, CA400 participantsCity of Hope Medical Center

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NCT07255729Recruiting

An Exosomal microRNA Signature for Preoperative Staging in Colon Cancer

Recent studies have highlighted the potential benefits of neoadjuvant chemotherapy (NAC) in colon cancer; however, its indication is generally limited to cases corresponding to pathological stage IIB ...

Duarte, CA400 participantsCity of Hope Medical Center

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NCT06820463Recruiting

A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

CRC is the third most common type of cancer diagnosed worldwide with developed countries at highest risk. The purpose of this study is to assess adverse events and change in disease activity when teli...

Duarte, CAPHASE2390 participantsAbbVie

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NCT03659448Recruiting

Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer

The performance of SGM-101, an intraoperative imaging agent, will be compared to that of standard "white light" visualization during surgical resections of colorectal cancer....

Duarte, CAPHASE3300 participantsSurgimab

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NCT07226115Recruiting

Splicing-based Predictive Learning for Individual Chemotherapy Evaluation in Colorectal Cancer

Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide. Although adjuvant chemotherapy improves survival after curative resection, its efficacy varies widely a...

Duarte, CA200 participantsCity of Hope Medical Center

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NCT05319314Recruiting

LYL273 for Patients With Relapsed or Refractory mCRC

This is a Phase 1/2 open-label, multicenter study evaluating the safety and efficacy of LYL273 in participants with relapsed or refractory metastatic colorectal cancer....

Duarte, CAPHASE1155 participantsLyell Immunopharma, Inc.

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NCT06528990Recruiting

Telehealth Intervention for Ostomy Self-Management

Over one million individuals in the U.S. have ostomies. An ostomy is a surgical procedure that creates an opening in the abdominal wall that allows bodily waste (urinary or fecal) to pass through into...

Duarte, CAPHASE2150 participantsCity of Hope Medical Center

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NCT07125729Recruiting

Minimal Residual Disease Testing for the Early Detection of Cancer Recurrence in Resectable Stage II-IV Colorectal Cancer Patients

This clinical trial compares minimal residual disease (MRD) testing with the Haystack blood test (assay) to the Signatera® assay for the early detection of the cancer returning (cancer recurrence) in ...

Duarte, CANA150 participantsCity of Hope Medical Center

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NCT06607458Recruiting

Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant Disease

The goal of this clinical trial is to learn if using a liver-directed therapy with high dose chemotherapy followed by approved cancer treatment to treat patients with colorectal cancer that has spread...

Duarte, CAPHASE290 participantsDelcath Systems Inc.

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NCT07321106Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

This study will investigate the safety, tolerability, pharmacokinetics, and anti-tumor activity of CBI-1214 in participants with advanced or metastatic Microsatellite Stable (MSS)/Microsatellite Insta...

Duarte, CAPHASE180 participantsCartography Biosciences

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NCT07544589Recruiting

A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers

This is a Phase 1, multicenter, open-label study of DISP-10, a combination therapy consisting of DV-10 (adenovirus) and idecabtagene vicleucel (ide-cel, BCMA-directed chimeric antigen receptor \[CAR\]...

Duarte, CAPHASE166 participantsDispatch Biotherapeutics

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About Colorectal Cancer Clinical Trials in Duarte

Colorectal cancer starts in the colon or rectum and is the third most common cancer diagnosed in both men and women. Early detection through screening significantly improves outcomes. Treatments include surgery, chemotherapy, radiation, and targeted therapies.

There are currently 17 colorectal cancer clinical trials recruiting participants in Duarte, CA. These studies are seeking a combined 5,723 participants. Research is being sponsored by City of Hope Medical Center, Summit Therapeutics, Hoffmann-La Roche and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Colorectal Cancer Clinical Trials in Duarte — FAQ

Are there colorectal cancer clinical trials in Duarte?

Yes, there are 17 colorectal cancer clinical trials currently recruiting in Duarte, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Duarte?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Duarte research site will contact you about next steps.

Are clinical trials in Duarte free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Duarte studies also compensate for your time and travel.

What colorectal cancer treatments are being tested?

The 17 active trials in Duarte are testing new therapies including novel drugs, biologics, and treatment approaches for colorectal cancer.

Data updated July 17, 2026 from ClinicalTrials.gov