3 Depression Clinical Trials in Durham, NC (2026)

Q: How do I join a clinical trial in Durham?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Durham research site will contact you.

Recruiting Depression Studies in Durham

NCT06538246Recruiting

Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors

Conditions treated in intensive care units (ICUs) such as the acute respiratory distress syndrome (ARDS), congestive heart failure, COVID pneumonia, and sepsis are common. These can lead to high rates...

Durham, NC400 participantsDuke University

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NCT06188923Recruiting

A New Intervention to Improve Function in Veterans With Anxiety and Depression

Anxiety and depression symptoms occur at high rates in Veteran populations and can significantly impact function, compromising the ability to work and to successfully form and maintain valued relation...

Durham, NC84 participantsVA Office of Research and Development

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NCT06759558Recruiting

Allopregnanolone (Zuranolone) in Post-stroke Depression

The goal of this Phase II clinical trial is to learn if the oral synthetic allopreganolone analog (zuranolone) is safe to take and is well tolerated by stroke survivors experiencing moderate to severe...

Durham, NC6 participantsDuke University

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About Depression Clinical Trials in Durham

Depression (major depressive disorder) is a common and serious mood disorder that negatively affects how you feel, think, and handle daily activities. It affects over 280 million people globally. Treatment includes psychotherapy, antidepressant medications, and brain stimulation therapies.

There are currently 3 depression clinical trials recruiting participants in Durham, NC. These studies are seeking a combined 490 participants. Research is being sponsored by Duke University, VA Office of Research and Development. Clinical trial participation is free and participants receive study-related medical care at no cost.

Depression Clinical Trials in Durham — FAQ

Are there depression clinical trials in Durham?

Yes, there are 3 depression clinical trials currently recruiting in Durham, NC. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Durham?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Durham research site will contact you about next steps.

Are clinical trials in Durham free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Durham studies also compensate for your time and travel.

What depression treatments are being tested?

The 3 active trials in Durham are testing new therapies including novel drugs, biologics, and treatment approaches for depression.

Data updated July 13, 2026 from ClinicalTrials.gov